The scorpion collections (Arachnida, Scorpiones) held in the Museo Regionale di Scienze Naturali of Turin (Italy)

Data and considerations about the history and contents of the scorpion collection housed in the Museo Regionale di Scienze Naturali of Turin (MRSN) are reported. Information on type material and important historical specimens are provided, as well as biographical notes about the major zoologists of the museum

Multinational Banking in Europe: Financial Stability and Regulatory Implications. Lessons from the Financial Crisis

This paper examines whether multinational banks have a stabilising or a destabilising role during times of financial distress. With a focus on Europe, it looks at how these banks‟ foreign affiliates have been faring during the recent financial crisis. It finds that retail and corporate lending of these foreign affiliates have been stable and even increasing between 2007 and 2009. This pattern is related to the functioning of the internal capital market through which these banks funnel funds across their units. The internal capital market has been an effective tool to support foreign affiliates in distress and to isolate their lending from the local availability of financial resources, notwithstanding the systemic nature of the recent crisis. This effect has been particularly large within the EU integrated financial market and for the EMU countries, thus showing complementarity between economic integration and multinational banks‟ internal capital markets. In light of these findings, this paper supports the call for an integration of the European supervisory and regulatory framework overseeing multinational banks. The analysis is based on an analytical framework which derives the main conditions under which the internal capital market can perform this support function under idiosyncratic and systemic stresses. The empirical evidence uses both aggregate evidence on foreign claims worldwide, and firm-level evidence on the behaviour of banking groups‟ affiliates, compared to standing alone national banks.multinational banking, financial stability, regulation and supervision, internal capital markets, financial crises

Distributed Raman optical amplification in phase coherent transfer of optical frequencies

We describe the application of Raman Optical-fiber Amplification (ROA) for the phase coherent transfer of optical frequencies in an optical fiber link. ROA uses the transmission fiber itself as a gain medium for bi-directional coherent amplification. In a test setup we evaluated the ROA in terms of on-off gain, signal-to-noise ratio, and phase noise added to the carrier. We transferred a laser frequency in a 200 km optical fiber link with an additional 16 dB fixed attenuator (equivalent to 275 km of fiber on a single span), and evaluated both co-propagating and counter-propagating amplification pump schemes, demonstrating nonlinear effects limiting the co-propagating pump configuration. The frequency at the remote end has a fractional frequency instability of 3e-19 over 1000 s with the optical fiber link noise compensation

Auxetic materials for MEMS: modeling, optimization and additive manufacturing

Auxetic materials are of interest because of enhanced material properties related to negative Poisson’s ratio, such as increased shear modulus, indentation resistance, fracture toughness, energy absorption, porosity/permeability variation with strain and synclastic curvature. In addition, the Poissons ratio does not depend on scale: deformation can take place at the nano- (molecular), [1], micro-[2], or even at the macro-level, [3]; the only requirement is the right combination of the geometry and the deformation mechanism. The most popular feature of auxetic structures is that it can expand in the direction perpendicular to an externally exerted tension. This property makes auxetic structures strongly appealing for MEMS applications (i.e. motion conversion and resonators) [4]. Here we present a full study of a re-entrant honeycomb structure which can be used in MEMS devices as motion conversion spring. The design of the proposed structure is obtained from a Matlab optimization procedure targeted to reach a Poisson’s ratio equal to -1. An additional nonlinear numerical simulation (see [5]) is done to verify the behavior of the structure under large deformations regime, which is the one required by the MEMS applications and then, a 3D-printed model (see [6]) of the optimized structure is obtained. Finally, a topology optimization is performed to obtain an auxetic structure that, in principle, can amplify the motion in the direction othogonal to the driving one. With this procedure there is no need to create an input structure from which the optimization procedure can start. Also for one of these optimized auxetic structures, an additional nonlinear numerical simulation is done

Frequency transfer via a two-way optical phase comparison on a multiplexed fiber network

We performed a two-way remote optical phase comparison on optical fiber. Two optical frequency signals were launched in opposite directions in an optical fiber and their phases were simultaneously measured at the other end. In this technique, the fiber noise was passively cancelled, and we compared two optical frequencies at the ultimate 1E-21 stability level. The experiment was performed on a 47 km fiber that is part of the metropolitan network for Internet traffic. The technique relies on the synchronous measurement of the optical phases at the two ends of the link, that is made possible by the use of digital electronics. This scheme offers several advantages with respect to active noise cancellation, and can be upgraded to perform more complex tasks

Identification and expression analysis of type II and type III Pi transporters in the opossum kidney cell line.

New Findings: What is the central question of this study? The opossum kidney (OK) cell line is the main in vitro model of proximal tubular Pi transport, but it is incomplete because only the NaPiIIa Pi transporter has been identified. What is the main finding and its importance? We have cloned and characterized the Pi transporters NaPiIIc, PiT1 and PiT2 from OK cells and have analysed the relevance of the four transporters to Pi transport. All four transporters are involved in the upregulated Pi transport of cells incubated using a low-Pi medium, and only PiT1 is not involved in basal transport. Abstract: The apical membrane of renal proximal tubular epithelial cells is the main controller of phosphate homeostasis, because it determines the rate of urinary Pi excretion. The opossum kidney (OK) cell line is a good model for studying this function, but only NaPiIIa (NaPi4) has been identified to date as a Pi transporter in this cell line. In this work, we have identified three additional Pi transporters that are present in OK cells: NaPiIIc, PiT1 and PiT2. All three sequences are similar to the corresponding orthologues, but PiT1 is missing the first transmembrane domain. Confluent cells exhibit characteristics of type II Pi transport, which increases with alkalinity and is inhibited by phosphonoformic acid (PFA), and they mainly express NaPiIIa and NaPiIIc, with a low abundance of PiT1 and PiT2. Proliferating cells show a higher expression of PiT1 and PiT2 and a low expression of NaPiIIa and NaPiIIc. Adaptation to a low Pi concentration for 24 h induces the expression of RNA from NaPiIIa and NaPiIIc, which is not prevented by actinomycin D. Small interfering RNA transfections revealed that PiT1 is not necessary for Pi transport, but it is necessary for adaptation to a low Pi, similar to NaPiIIa and PiT2. Our study reveals the complexity of the coordination between the four Pi transporters, the variability of RNA expression according to confluence and the heterogeneous correlation between Pi transport and RNA levels

Moving constraints as stabilizing controls in classical mechanics

The paper analyzes a Lagrangian system which is controlled by directly assigning some of the coordinates as functions of time, by means of frictionless constraints. In a natural system of coordinates, the equations of motions contain terms which are linear or quadratic w.r.t.time derivatives of the control functions. After reviewing the basic equations, we explain the significance of the quadratic terms, related to geodesics orthogonal to a given foliation. We then study the problem of stabilization of the system to a given point, by means of oscillating controls. This problem is first reduced to the weak stability for a related convex-valued differential inclusion, then studied by Lyapunov functions methods. In the last sections, we illustrate the results by means of various mechanical examples.Comment: 52 pages, 4 figure

Mechanism of ferritin iron uptake: activity of the H-chain and deletion mapping of the ferro-oxidase site. A study of iron uptake and ferro-oxidase activity of human liver, recombinant H-chain ferritins, and of two H-chain deletion mutants.

To study the functional differences between human ferritin H- and L-chains and the role of the protein shell in the formation and growth of the ferritin iron core, we have compared the kinetics of iron oxidation and uptake of ferritin purified from human liver (90% L) and of the H-chain homopolymer overproduced in Escherichia coli (100% H). As a control for iron autocatalytic activity, we analyzed the effect of Fe(III) on the iron uptake reaction. The results show that the H-chain homopolymer has faster rates of iron uptake and iron oxidation than liver ferritin in all the conditions analyzed and that the difference is reduced in the conditions in which iron autocatalysis in high: i.e. at pH 7 and in presence of iron core. We have also analyzed the properties of two engineered H-chains, one lacking the last 22 amino acids at the carboxyl terminus and the other missing the first 13 residues at the amino terminus. These mutant proteins assemble in ferritin-like proteins and maintain the ability to catalyze iron oxidation. The deletion at the carboxyl terminus, however, prevents the formation of a stable iron core. It is concluded that the ferritin H-chain has an iron oxidation site which is separated from the sites of iron transfer and hydrolysis and that either the integrity of the molecule or the presence of the amino acid sequences forming the hydrophobic channel is necessary for iron core formation