37 research outputs found

    3D Object Recognition Based On Constrained 2D Views

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    The aim of the present work was to build a novel 3D object recognition system capable of classifying man-made and natural objects based on single 2D views. The approach to this problem has been one motivated by recent theories on biological vision and multiresolution analysis. The project's objectives were the implementation of a system that is able to deal with simple 3D scenes and constitutes an engineering solution to the problem of 3D object recognition, allowing the proposed recognition system to operate in a practically acceptable time frame. The developed system takes further the work on automatic classification of marine phytoplank- (ons, carried out at the Centre for Intelligent Systems, University of Plymouth. The thesis discusses the main theoretical issues that prompted the fundamental system design options. The principles and the implementation of the coarse data channels used in the system are described. A new multiresolution representation of 2D views is presented, which provides the classifier module of the system with coarse-coded descriptions of the scale-space distribution of potentially interesting features. A multiresolution analysis-based mechanism is proposed, which directs the system's attention towards potentially salient features. Unsupervised similarity-based feature grouping is introduced, which is used in coarse data channels to yield feature signatures that are not spatially coherent and provide the classifier module with salient descriptions of object views. A simple texture descriptor is described, which is based on properties of a special wavelet transform. The system has been tested on computer-generated and natural image data sets, in conditions where the inter-object similarity was monitored and quantitatively assessed by human subjects, or the analysed objects were very similar and their discrimination constituted a difficult task even for human experts. The validity of the above described approaches has been proven. The studies conducted with various statistical and artificial neural network-based classifiers have shown that the system is able to perform well in all of the above mentioned situations. These investigations also made possible to take further and generalise a number of important conclusions drawn during previous work carried out in the field of 2D shape (plankton) recognition, regarding the behaviour of multiple coarse data channels-based pattern recognition systems and various classifier architectures. The system possesses the ability of dealing with difficult field-collected images of objects and the techniques employed by its component modules make possible its extension to the domain of complex multiple-object 3D scene recognition. The system is expected to find immediate applicability in the field of marine biota classification

    Differentiation of acute and four-week old myocardial infarct with Gd(ABE-DTTA)-enhanced CMR

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    <p>Abstract</p> <p>Background</p> <p>Standard extracellular cardiovascular magnetic resonance (CMR) contrast agents (CA) do not provide differentiation between acute and older myocardial infarcts (MI). The purpose of this study was to develop a method for differentiation between acute and older myocardial infarct using myocardial late-enhancement (LE) CMR by a new, low molecular weight contrast agent.</p> <p>Dogs (n = 6) were studied in a closed-chest, reperfused, double myocardial infarct model. Myocardial infarcts were generated by occluding the Left Anterior Descending (LAD) coronary artery with an angioplasty balloon for 180 min, and four weeks later occluding the Left Circumflex (LCx) coronary artery for 180 min. LE images were obtained on day 3 and day 4 after second myocardial infarct, using Gd(DTPA) (standard extracellular contrast agent) and Gd(ABE-DTTA) (new, low molecular weight contrast agent), respectively. Triphenyltetrazolium chloride (TTC) histomorphometry validated existence and location of infarcts. Hematoxylin-eosin and Masson's trichrome staining provided histologic evaluation of infarcts.</p> <p>Results</p> <p>Gd(ABE-DTTA) or Gd(DTPA) highlighted the acute infarct, whereas the four-week old infarct was visualized by Gd(DTPA), but not by Gd(ABE-DTTA). With Gd(ABE-DTTA), the mean ± SD signal intensity enhancement (SIE) was 366 ± 166% and 24 ± 59% in the acute infarct and the four-week old infarct, respectively (P < 0.05). The latter did not differ significantly from signal intensity in healthy myocardium (P = NS). Gd(DTPA) produced signal intensity enhancements which were similar in acute (431 ± 124%) and four-week old infarcts (400 ± 124%, P = NS), and not statistically different from the Gd(ABE-DTTA)-induced SIE in acute infarct. The existence and localization of both infarcts were confirmed by triphenyltetrazolium chloride (TTC). Histologic evaluation demonstrated coagulation necrosis, inflammation, and multiple foci of calcification in the four day old infarct, while the late subacute infarct showed granulation tissue and early collagen deposition.</p> <p>Conclusions</p> <p>Late enhancement CMR with separate administrations of standard extracellular contrast agent, Gd(DTPA), and the new low molecular weight contrast agent, Gd(ABE-DTTA), differentiates between acute and late subacute infarct in a reperfused, double infarct, canine model.</p

    Three is the magic number -- distance measurement of NGC 3147 using SN 2021hpr and its siblings

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    The nearby spiral galaxy NGC 3147 hosted three Type Ia supernovae (SNe Ia) in the past decades, which have been subjects of intense follow-up observations. Simultaneous analysis of their data provides a unique opportunity for testing the different light curve fitting methods and distance estimations. The detailed optical follow-up of SN 2021hpr allows us to revise the previous distance estimations to NGC 3147, and compare the widely used light curve fitting algorithms to each other. After the combination of the available and newly published data of SN 2021hpr, its physical properties can be also estimated with higher accuracy. We present and analyse new BVgriz and Swift photometry of SN 2021hpr to constrain its general physical properties. Together with its siblings, SNe 1997bq and 2008fv, we cross-compare the individual distance estimates of these three SNe given by the SALT code, and also check their consistency with the results from the MLCS2k2 method. The early spectral series of SN 2021hpr are also fit with the radiative spectral code TARDIS in order to verify the explosion properties and constrain the chemical distribution of the outer ejecta. After combining the distance estimates for the three SNe, the mean distance to their host galaxy, NGC 3127, is 42.5 ±\pm 1.0 Mpc, which matches with the distance inferred by the most up-to-date LC fitters, SALT3 and BayeSN. We confirm that SN~2021hpr is a Branch-normal Type Ia SN that ejected 1.12±0.28\sim 1.12 \pm 0.28 M_\odot from its progenitor white dwarf, and synthesized 0.44±0.14\sim 0.44 \pm 0.14 M_\odot of radioactive 56^{56}Ni.Comment: 16 pages, 17 figures, 11 tables; accepted for publication in A&

    Identification of herpesvirus transcripts from genomic regions around the replication origins

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    Long-read sequencing (LRS) techniques enable the identification of full-length RNA molecules in a single run eliminating the need for additional assembly steps. LRS research has exposed unanticipated transcriptomic complexity in various organisms, including viruses. Herpesviruses are known to produce a range of transcripts, either close to or overlapping replication origins (Oris) and neighboring genes related to transcription or replication, which possess confirmed or potential regulatory roles. In our research, we employed both new and previously published LRS and short-read sequencing datasets to uncover additional Ori-proximal transcripts in nine herpesviruses from all three subfamilies (alpha, beta and gamma). We discovered novel long non-coding RNAs, as well as splice and length isoforms of mRNAs. Moreover, our analysis uncovered an intricate network of transcriptional overlaps within the examined genomic regions. We demonstrated that herpesviruses display distinct patterns of transcriptional overlaps in the vicinity of or at the Oris. Our findings suggest the existence of a ‘super regulatory center’ in the genome of alphaherpesviruses that governs the initiation of both DNA replication and global transcription through multilayered interactions among the molecular machineries

    Constraints on the physical properties of Type Ia supernovae from photometry

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    We present a photometric study of 17 Type Ia supernovae (SNe) based on multi-color (Bessell BVRI) data taken at Piszkesteto mountain station of Konkoly Observatory, Hungary between 2016 and 2018. We analyze the light curves (LCs) using the publicly available LC-fitter SNooPy2 to derive distance and reddening information. The bolometric LCs are fit with a radiation-diffusion Arnett-model to get constraints on the physical parameters of the ejecta: the optical opacity, the ejected mass and the expansion velocity in particular. We also study the pre-maximum (B-V) color evolution by comparing our data with standard delayed detonation and pulsational delayed detonation models, and show that the Ni56 masses of the models that fit the (B-V) colors are consistent with those derived from the bolometric LC fitting. We find similar correlations between the ejecta parameters (e.g. ejecta mass, or Ni56 mass vs decline rate) as published recently by Scalzo et al. (2019

    Pilot analysis of the usefulness of mortality risk score systems at resuscitated patients

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    Introduction: Sudden cardiac death is one of the most significant cardiovascular causes of death worldwide. Although there have been immense methodological and technical advances in the field of cardiopulmonary resuscitation and following intensive care in the last decade, currently there are only a few validated risk-stratification scoring systems for the quick and reliable estimation of the mortality risk of these patients at the time of admission to the intensive care unit. Objective: Our aim was to correlate the mortality prediction risk points calculated by CardShock Risk Score (CSRS) and modified (m) CSRS based on the admission data of the post-cardiac arrest syndrome (PCAS) patients. Methods: The medical records of 172 out-of-hospital resuscitated cardiac arrest patients, who were admitted at the Heart and Vascular Centre of Semmelweis University, were screened retrospectively. Out of the 172 selected patients, 123 were eligible for inclusion to calculate CSRS and mCSRS. Based on CSRS score, we generated three different groups of patients, with scores 1 to 3, 4 to 6, and 7+, respectively. Mortality data of the groups were compared by log-rank test. Results: Mean age of the patients was 63.6 years (69% male), the cause of sudden cardiac death was acut coronary syndrome in 80% of the cases. The early and late mortality was predicted by neurological status, serum lactate level, renal function, initial rhythm, and the need of catecholamines. Using mCSRS, a significant survival difference was proven in between the groups "1-3" vs "4-6" (p Conclusion: Compared to the CSRS, the mCSRS expanded with the 2 additional weighting points differentiates more specifically the low-moderate and high survival groups in the PCAS patient population treated in our institute.Peer reviewe
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