448 research outputs found
Understanding visual map formation through vortex dynamics of spin Hamiltonian models
The pattern formation in orientation and ocular dominance columns is one of
the most investigated problems in the brain. From a known cortical structure,
we build spin-like Hamiltonian models with long-range interactions of the
Mexican hat type. These Hamiltonian models allow a coherent interpretation of
the diverse phenomena in the visual map formation with the help of relaxation
dynamics of spin systems. In particular, we explain various phenomena of
self-organization in orientation and ocular dominance map formation including
the pinwheel annihilation and its dependency on the columnar wave vector and
boundary conditions.Comment: 4 pages, 15 figure
Pro- and Anti-Inflammatory Cytokines during Immune Stimulation: Modulation of Iron Status and Red Blood Cell Profile
Forty-eight patients were subdivided according to C-reactive protein (CRP) levels, resulting in 19 patients with normal (2.8 ± 2.8 mg/L) and 29 with elevated (82.2 ± 76.2 mg/L) CRP levels. The elevated CRP group had iron and red blood cell (RBC) profiles characteristic of chronic immune stimulation (CIS), and the normal CRP group, profiles of true iron deficiency. Normal relationships between storage iron, bioavailable iron, and RBC indices were absent in the elevated CRP group—implying the role of iron as major determinant of the RBC profile to be diminished during CIS. The elevated CRP group had significant increases in proinflammatory cytokines (INF-γ, TNF-α, Il-1β, Il-6, and Il-8). Anti-inflammatory cytokine levels were normal, except for Il-10, supporting previous indications that Il-10 contributes to reducing bioavailable iron. Regression analysis suggested decreases in transferrin to be related to increases in Il-8 and an increase in ferritin to be related to a decrease in Il-12 levels. TGF-β levels were positively related to transferrin and negatively to ferritin
WFPC2 Observations of the Hubble Deep Field-South
The Hubble Deep Field-South observations targeted a high-galactic-latitude
field near QSO J2233-606. We present WFPC2 observations of the field in four
wide bandpasses centered at roughly 300, 450, 606, and 814 nm. Observations,
data reduction procedures, and noise properties of the final images are
discussed in detail. A catalog of sources is presented, and the number counts
and color distributions of the galaxies are compared to a new catalog of the
HDF-N that has been constructed in an identical manner. The two fields are
qualitatively similar, with the galaxy number counts for the two fields
agreeing to within 20%. The HDF-S has more candidate Lyman-break galaxies at z
> 2 than the HDF-N. The star-formation rate per unit volume computed from the
HDF-S, based on the UV luminosity of high-redshift candidates, is a factor of
1.9 higher than from the HDF-N at z ~ 2.7, and a factor of 1.3 higher at z ~ 4.Comment: 93 pages, 25 figures; contains very long table
Data report: X-ray fluorescence core scanning of IODP Site U1474 sediments, Natal Valley, southwest Indian Ocean, Expedition 361
X-ray fluorescence (XRF) core scanning was conducted on core sections from International Ocean Discovery Program Site U1474, located in the Natal Valley off the coast of South Africa. The data were collected at 2 mm resolution along the 255 m length of the splice, but this setting resulted in noisy data. This problem was addressed by applying a 10 point running sum on the XRF data prior to converting peak area to element intensities. This effectively integrates 10 measurements into 1, representing an average over 2 cm resolution, and significantly improves noise in the data. With 25 calibration samples, whose element concentrations were derived using inductively coupled plasma–optical emission spectrometry, the XRF measurements were converted to concentrations using a univariate log-ratio calibration method. The resulting concentrations of terrigenously derived major elements (Al, Si, K, Ti, and Fe) are anticorrelated with Ca concentrations, indicating the main control on sediment chemistry is the variable proportion of terrigenous to in situ produced carbonate material
Piecing Together the American Voting Puzzle: How Votersâ Personalities and Judgments of Issue Importance Mattered in the 2016 Presidential Election
In the wake of the 2016 election, which surprised pundits and voters on both the left and the right, there has been renewed interest in understanding what predicts American votersâ choices. In this article, we investigate the roles of personality and issue importance in how people voted in the 2016 U.S. election. In this longitudinal study of 403 MTurk workers who voted in the election, we assessed the relations between personality (openness, social dominance orientation, and national identity importance) and issue importance (group rights and social justice, economic rights, and individual and national rights), and voting for Clinton or Trump. Our results indicate that both individual differences and issue importance as measured in July 2016 predicted votes in November. We also found that the links between personality and voting were mediated by issue importance. Implications for political psychology and the study of personality, campaign issues, and voting behavior are discussed.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/146841/1/asap12157.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/146841/2/asap12157_am.pd
Personalised service? Changing the role of the government librarian
Investigates the feasibility of personalised information service in a government department. A qualitative methodology explored stakeholder opinions on the remit, marketing, resourcing and measurement of the service. A questionnaire and interviews gathered experiences of personalised provision across the government sector. Potential users were similarly surveyed to discuss how the service could meet their needs. Data were analysed using coding techniques to identify emerging theory. Lessons learned from government librarians centred on clarifying requirements, balancing workloads and selective marketing. The user survey showed low usage and awareness of existing specialist services, but high levels of need and interest in services repackaged as a tailored offering. Fieldwork confirmed findings from the literature on the scope for adding value through information management advice, information skills training and substantive research assistance and the need to understand business processes and develop effective partnerships. Concluding recommendations focus on service definition, strategic marketing, resource utilisation and performance measurement
R.A.Fisher, design theory, and the Indian connection
Design Theory, a branch of mathematics, was born out of the experimental
statistics research of the population geneticist R. A. Fisher and of Indian
mathematical statisticians in the 1930s. The field combines elements of
combinatorics, finite projective geometries, Latin squares, and a variety of
further mathematical structures, brought together in surprising ways. This
essay will present these structures and ideas as well as how the field came
together, in itself an interesting story.Comment: 11 pages, 3 figure
The Hubble Space Telescope Treasury Program on the Orion Nebula Cluster
The Hubble Space Telescope (HST) Treasury Program on the Orion Nebula Cluster
has used 104 orbits of HST time to image the Great Orion Nebula region with the
Advanced Camera for Surveys (ACS), the Wide-Field/Planetary Camera 2 (WFPC2)
and the Near Infrared Camera and Multi Object Spectrograph (NICMOS) instruments
in 11 filters ranging from the U-band to the H-band equivalent of HST. The
program has been intended to perform the definitive study of the stellar
component of the ONC at visible wavelengths, addressing key questions like the
cluster IMF, age spread, mass accretion, binarity and cirumstellar disk
evolution. The scanning pattern allowed to cover a contiguous field of
approximately 600 square arcminutes with both ACS and WFPC2, with a typical
exposure time of approximately 11 minutes per ACS filter, corresponding to a
point source depth AB(F435W) = 25.8 and AB(F775W)=25.2 with 0.2 magnitudes of
photometric error. We describe the observations, data reduction and data
products, including images, source catalogs and tools for quick look preview.
In particular, we provide ACS photometry for 3399 stars, most of them detected
at multiple epochs, WFPC2 photometry for 1643 stars, 1021 of them detected in
the U-band, and NICMOS JH photometry for 2116 stars. We summarize the early
science results that have been presented in a number of papers. The final set
of images and the photometric catalogs are publicly available through the
archive as High Level Science Products at the STScI Multimission Archive hosted
by the Space Telescope Science Institute.Comment: Accepted for publication on the Astrophysical Journal Supplement
Series, March 27, 201
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