1,499 research outputs found
An evaluation of the performance of three semantic background knowledge sources in comparative anatomy
In this paper we evaluate the performance and usefulness of three semantic background knowledge sources for predicting synonymous anatomical terms across species boundaries. The reference sources under evaluation are UMLS, FMA-OBO and WordNet, which are applied to the anatomical ontologies of mouse and zebrafish. Our results show that the use of specialized knowledge sources leads to highly accurate predictions, verified through complete manual curation, which can be further improved by combining multiple of said sources. We argue that these three references complement each other in terms of granularity and specificity. From our results we conclude that these references can be used to create reliable ontology mappings with minimal human supervision
Crafting Natures : Aristotle on Animal Design
It is a commonplace in Aristotelian scholarship that the forms of living beings and the animal species to which they give rise are “fixed.” However, Aristotle’s biological works often stress the flexibility of nature during the development of animals. The purpose of this paper is twofold: first, to delineate the range of flexibility that Aristotle takes natures to have in the design of animals; and second, to draw out the implications of this for Aristotle’s embryology and theory of natural teleology
Evidence for RNA recombination between distinct isolates of Pepino mosaic virus.
Genetic recombination plays an important role in the evolution of virus genomes. In this study we analyzed publicly available genomic sequences of Pepino mosaic virus (PepMV) for recombination events using several bioinformatics tools. The genome-wide analyses not only confirm the presence of previously found recombination events in PepMV but also provide the first evidence for double recombinant origin of the US2 isolate
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