Acceptance of co-operative education practice by the academic staff at Technikon Southern Africa.

Technikons advocate the practice of co-operative education, which is an educational strategy that integrates learning through productive work with the theoretical curriculum. However, only 35% of theTechnikon SA programmes have a compulsory experiential learning component. Grounded theory research was undertaken to determine some of the basic assumptions of Technikon SA’s academic staff in this regard. Rather than starting out with a specific research problem, grounded theory explores an area of interest and allows what is relevant to emerge. Semi-structured interviews with four open-ended questions, were conducted with a stratified-random sample of 25 teaching staff at Technikon SA. It was found that, although there is some willing compliance and belief in co-operative education, it is not indicative of the organisational culture of Technikon SA

Acceptance of co-operatve education practice by the Academic Staff at Technikon South Africa

Technikons advocate the practice of co-operative education, which is an educational strategy that integrates learning through productive work with the theoretical curriculum. However, only 35% of theTechnikon SA programmes have a compulsory experiential learning component. Grounded theory research was undertaken to determine some of the basic assumptions of Technikon SA’s academic staff in this regard. Rather than starting out with a specific research problem, grounded theory explores an area of interest and allows what is relevant to emerge. Semi-structured interviews with four open-ended questions, were conducted with a stratified-random sample of 25 teaching staff at Technikon SA. It was found that, although there is some willing compliance and belief in co-operative education, it is not indicative of the organisational culture of Technikon SA. Opsomming Technikons propageer die beoefening van ko˛peratiewe onderwys,’n opvoedkundige strategiewat leer deur produktiewewerkservaring integreermet die teoretiese kurrikulum. ByTechnikon SAegter, het slegs sowat 35% van die formele programme ’n verpligte leerervarings komponent.Teoretiese-begrondings navorsingsmetodologie is gebruik omsekere basiese veronderstellings van akademiese personeel te bepaal. Eerder as om’n spesifieke navorsingsprobleemas vertrekpunt te gebruik, ondersoek teoretiese-begronding’n areavan belang en laat die metodiek die relevante sake toe omte voorskyn te kom. Semi-gestruktureerde onderhoude,met vier ope vrae, is gevoer met ’n gestratifiseerde eweskansige steekproef van 25 akademiese personeellede vanTechnikon SA. Daar is bevind dat alhoewel daar beperkte oortuiging en gewillige uitlewing van kooperatiewe onderwys is, is dit nie beduidend as kenmerkend van die organisasie kultuur vanTechnikon SA nie

Assessment of the realisation of the right to adequate food in the Blue Crane Route (Eastern Cape, South Africa)

To assess whether the right to adequate food (RtF) is realised by children and primary caregivers and what actions are required to fully realise this right.A cross-sectional, descriptive study was undertaken using a mixed-methods approach.Rural and urban primary caregivers of children (one to five years old) were recruited if they had resided in the Blue Crane Route (Eastern Cape) for at least six months. Purposefully selected key informants (KIs) involved in nutrition and food security, health or governance participated in in-depth interviews.Primary caregivers responded to interviewer-administered questionnaires (IAQ) (N = 161), which investigated various indicators supporting the realisation of the RtF. Statistical analysis of quantitative data examined relationships between urban and rural participants. Significance was considered at p < 0.05. In-depth interviews with key informants (KIs) examined the perceptions of 11 prominent community leaders. Qualitative data were coded deductively and common themes identified

Solvent and conformation dependence of amide I vibrations in peptides and proteins containing proline

We present a mixed quantum-classical model for studying the amide I vibrational dynamics (predominantly CO stretching) in peptides and proteins containing proline. There are existing models developed for determining frequencies of and couplings between the secondary amide units. However, these are not applicable to proline because this amino acid has a tertiary amide unit. Therefore, a new parametrization is required for infrared-spectroscopic studies of proteins that contain proline, such as collagen, the most abundant protein in humans and animals. Here, we construct the electrostatic and dihedral maps accounting for solvent and conformation effects on frequency and coupling for the proline unit. We examine the quality and the applicability of these maps by carrying out spectral simulations of a number of peptides with proline in D2O and compare with experimental observations.Netherlands Organization for Scientific Research (VIDI grant)National Science Foundation (U.S.) ((NSF) CHE-0911107

A 9-Month Hubble Space Telescope Near-UV Survey of M87. I. Light and Color Curves of 94 Novae, and a Re-determination of the Nova Rate

M87 has been monitored with a cadence of 5 days over a 9 month-long span through the near-ultraviolet (NUV:F275W) and optical (F606W) filters of the Wide Field Camera 3 (WFC3) of the $\textit{Hubble Space Telescope}$. This unprecedented dataset yields the NUV and optical light and color curves of 94 M87 novae, characterizing the outburst and decline properties of the largest extragalactic nova dataset in the literature (after M31 and M81). We test and confirm nova modelers' prediction that recurrent novae cannot erupt more frequently that once every 45 days; show that there are zero rapidly recurring novae in the central $\sim$ 1/3 of M87 with recurrence times $<$ 130 days; demonstrate that novae closely follow the K-band light of M87 to within a few arcsec of the galaxy nucleus; show that nova NUV light curves are as heterogeneous as their optical counterparts, and usually peak 5 to 30 days after visible light maximum; determine our observations' annual detection completeness to be 71 - 77\%; and measure the rate Rnova of nova eruptions in M87 as $352_{-37}^{+37}$/yr. The corresponding luminosity-specific classical nova rate for this galaxy is $7.91_{-1.20}^{+1.20}/yr/10^{10}L_\odot,_{K}$. These rates confirm that ground-based observations of extragalactic novae miss most faint, fast novae and those near the centers of galaxies. An annual M87 nova rate of 300 or more seems inescapable. A luminosity-specific nova rate of $\sim$ $7 - 10/yr/10^{10}L_\odot,_{K}$ in ${\it all}$ types of galaxies is indicated by the data available in 2023.Comment: Accepted/In Press in ApJS; 3 Tables, 108 Figures, 180 page

Fabrication of Mullite Body Using Superplastic Transient Phase

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65799/1/j.1151-2916.1992.tb05542.x.pd

Ergothioneine Biosynthesis and Functionality in the Opportunistic Fungal Pathogen, Aspergillus fumigatus.

Ergothioneine (EGT; 2-mercaptohistidine trimethylbetaine) is a trimethylated and sulphurised histidine derivative which exhibits antioxidant properties. Here we report that deletion of Aspergillus fumigatus egtA (AFUA_2G15650), which encodes a trimodular enzyme, abrogated EGT biosynthesis in this opportunistic pathogen. EGT biosynthetic deficiency in A. fumigatus significantly reduced resistance to elevated H2O2 and menadione, respectively, impaired gliotoxin production and resulted in attenuated conidiation. Quantitative proteomic analysis revealed substantial proteomic remodelling in ΔegtA compared to wild-type under both basal and ROS conditions, whereby the abundance of 290 proteins was altered. Specifically, the reciprocal differential abundance of cystathionine γ-synthase and β-lyase, respectively, influenced cystathionine availability to effect EGT biosynthesis. A combined deficiency in EGT biosynthesis and the oxidative stress response regulator Yap1, which led to extreme oxidative stress susceptibility, decreased resistance to heavy metals and production of the extracellular siderophore triacetylfusarinine C and increased accumulation of the intracellular siderophore ferricrocin. EGT dissipated H2O2 in vitro, and elevated intracellular GSH levels accompanied abrogation of EGT biosynthesis. EGT deficiency only decreased resistance to high H2O2 levels which suggests functionality as an auxiliary antioxidant, required for growth at elevated oxidative stress conditions. Combined, these data reveal new interactions between cellular redox homeostasis, secondary metabolism and metal ion homeostasis