745 research outputs found
ø-threshold and ø-tolerance chain graphs
AbstractIn this paper we introduce a class of graphs called ø-threshold graphs which generalize threshold graphs. These graphs are studied for various functions ø that include “max” and “min” as special cases. The graphs are then shown to fit into the more general setting of ø-tolerance intersection graphs previously introduced by Jacobson, McMorris, and Mulder. Finally, ø-tolerance chain graphs are studied for the same functions ø mentioned above
Legislative Resolution Presented to Celesete Fitzgerald for the New Jerseyans for Alternatives to the Death Penalty
Physiological Responses of Thoracic Load Carriage During Walking in Men and Women
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An investigation in to the asymmetries of the equine hoof and the influence of body weight and height on hoof conformation
Cold Atmospheric Plasma Induces Silver Nanoparticle Uptake, Oxidative Dissolution and Enhanced Cytotoxicity in Glioblastoma Multiforme Cells
Silver nanoparticles (AgNP) emerged as a promising reagent for cancer therapy with oxidative stress implicated in the toxicity. Meanwhile, studies reported cold atmospheric plasma (CAP) generation of reactive oxygen and nitrogen species has selectivity towards cancer cells. Gold nanoparticles display synergistic cytotoxicity when combined with CAP against cancer cells but there is a paucity of information using AgNP, prompting to investigate the combined effects of CAP using dielectric barrier discharge system (voltage of 75 kV, current is 62.5 mA, duty cycle of 7.5kVA and input frequency of 50–60Hz) and 10 nm PVA-coated AgNP using U373MG Glioblastoma Multiforme cells. Cytotoxicity in U373MG cells was \u3e100-fold greater when treated with both CAP and PVA-AgNP compared with either therapy alone (IC50 of 4.30 μg/mL with PVA-AgNP alone compared with 0.07 μg/mL after 25s CAP and 0.01 μg/mL 40s CAP). Combined cytotoxicity was ROS-dependent and was prevented using N-Acetyl Cysteine. A novel darkfield spectral imaging method investigated and quantified AgNP uptake in cells determining significantly enhanced uptake, aggregation and subcellular accumulation following CAP treatment, which was confirmed and quantified using atomic absorption spectroscopy. The results indicate that CAP decreases nanoparticle size, decreases surface charge distribution of AgNP and induces uptake, aggregation and enhanced cytotoxicity in vitro
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