ASTP chemical and microbiological analysis of potable water

The Apollo-Soyuz Test Project procedures for potable water system servicing and the results of preflight and postflight chemical and microbiological analyses of the water are discussed. Tables show results of the analyses. The effectiveness of the water system is evaluated

Three-dimensional coating and rimming flow: a ring of fluid on a rotating horizontal cylinder

The steady three-dimensional flow of a thin, slowly varying ring of Newtonian fluid on either the outside or the inside of a uniformly rotating large horizontal cylinder is investigated. Specifically, we study “full-ring” solutions, corresponding to a ring of continuous, finite and non-zero thickness that extends all the way around the cylinder. In particular, it is found that there is a critical solution corresponding to either a critical load above which no full-ring solution exists (if the rotation speed is prescribed) or a critical rotation speed below which no full-ring solution exists (if the load is prescribed). We describe the behaviour of the critical solution and, in particular, show that the critical flux, the critical load, the critical semi-width and the critical ring profile are all increasing functions of the rotation speed. In the limit of small rotation speed, the critical flux is small and the critical ring is narrow and thin, leading to a small critical load. In the limit of large rotation speed, the critical flux is large and the critical ring is wide on the upper half of the cylinder and thick on the lower half of the cylinder, leading to a large critical load.\ud \ud We also describe the behaviour of the non-critical full-ring solution, and, in particular, show that the semi-width and the ring profile are increasing functions of the load but, in general, non-monotonic functions of the rotation speed. In the limit of large rotation speed, the ring approaches a limiting non-uniform shape, whereas in the limit of small load, the ring is narrow and thin with a uniform parabolic profile. Finally, we show that, while for most values of the rotation speed and the load the azimuthal velocity is in the same direction as the rotation of the cylinder, there is a region of parameter space close to the critical solution for sufficiently small rotation speed in which backflow occurs in a small region on the right-hand side of the cylinder

Thermoviscous Coating and Rimming Flow

A comprehensive description is obtained of steady thermoviscous (i.e. with temperature-dependent viscosity) coating and rimming flow on a uniformly rotating horizontal cylinder that is uniformly hotter or colder than the surrounding atmosphere. It is found that, as in the corresponding isothermal problem, there is a critical solution with a corresponding critical load (which depends, in general, on both the Biot number and the thermoviscosity number) above which no ``full-film'' solutions corresponding to a continuous film of fluid covering the entire outside or inside of the cylinder exist. The effect of thermoviscosity on both the critical solution and the full-film solution with a prescribed load is described. In particular, there are no full-film solutions with a prescribed load M for any value of the Biot number when M is greater than or equal to M_{c0} divided by the square root of f for positive thermoviscosity number and when M is greater than M_{c0} for negative thermoviscosity number, where f is a monotonically decreasing function of the thermoviscosity number and M_{c0} = 4.44272 is the critical load in the constant-viscosity case. It is also found that when the prescribed load M is less than 1.50315 there is a narrow region of the Biot number - thermoviscosity number parameter plane in which backflow occurs

A single mutation in the envelope protein modulates flavivirus antigenicity, stability, and pathogenesis

The structural flexibility or 'breathing' of the envelope (E) protein of flaviviruses allows virions to sample an ensemble of conformations at equilibrium. The molecular basis and functional consequences of virus conformational dynamics are poorly understood. Here, we identified a single mutation at residue 198 (T198F) of the West Nile virus (WNV) E protein domain I-II hinge that regulates virus breathing. The T198F mutation resulted in a ~70-fold increase in sensitivity to neutralization by a monoclonal antibody targeting a cryptic epitope in the fusion loop. Increased exposure of this otherwise poorly accessible fusion loop epitope was accompanied by reduced virus stability in solution at physiological temperatures. Introduction of a mutation at the analogous residue of dengue virus (DENV), but not Zika virus (ZIKV), E protein also increased accessibility of the cryptic fusion loop epitope and decreased virus stability in solution, suggesting that this residue modulates the structural ensembles sampled by distinct flaviviruses at equilibrium in a context dependent manner. Although the T198F mutation did not substantially impair WNV growth kinetics in vitro, studies in mice revealed attenuation of WNV T198F infection. Overall, our study provides insight into the molecular basis and the in vitro and in vivo consequences of flavivirus breathing

Self-reported “communication technology” usage in patients attending a cardiology outpatient clinic in a remote regional hospital

Peer reviewedPublisher PD

Eligibility and enrollment in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC)--27 states and New York City, 2007-2008.

The national Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) provides nutrition education, growth monitoring, breastfeeding promotion and support, and food to low-income pregnant or postpartum women, infants, and children aged <5 years. Several studies have linked WIC services with improved maternal and infant health outcomes. Most population-based studies have lacked information needed to identify eligible women who are not receiving WIC services and might be at risk for poor health outcomes. This report uses multistate, population-based 2007-2008 survey data from CDC's Pregnancy Risk Assessment Monitoring System (PRAMS) and California's Maternal and Infant Health Assessment (MIHA) to estimate how many women were eligible but not enrolled in WIC during pregnancy and to describe their characteristics and their prevalence of markers of risk for poor maternal or infant health outcomes. Approximately 17% of all women surveyed were eligible but not enrolled in WIC during pregnancy. The proportion of women eligible for WIC and WIC participation rates varied by state. WIC participants had higher prevalences of markers of risk for poor maternal or infant health outcomes than eligible nonparticipants, but both groups had higher prevalences of risk markers than ineligible women, suggesting that many eligible women and their children might benefit from WIC services. The results of this analysis can help identify the scope of WIC outreach needed to include more eligible nonparticipants in WIC and whom to target

The QBO and interannual variation in total ozone

Garcia and Soloman (1987) have noted that the October monthly mean minimum total ozone amounts south of 30 S were modulated by a quasibiennial oscillation (QBO) signal. The precise mechanism behind this effect, however, is unclear. Is the modulation brought about by the circulation-produced QBO signal in the ozone concentration itself, or does the temperature QBO modulate the formation of polar stratospheric clouds (PSCs), leading to changes in the chemically induced Antarctic spring ozone decline rate. Or is some other phenomenon involved. To investigate the means through which the QBO effect occurs, a series of correlation studies has been made between polar ozone and QBO signal in ozone and temperature

The Metallicity and Reddening of Stars in the Inner Galactic Bulge

We present a preliminary analysis of K, J-K color magnitude diagrams (CMDs) for 7 different positions on or close to the minor axis of the Milky Way at Galactic latitudes between +0.1^\circ and -2.8^\circ. From the slopes of the (linear) giant branches in these CMDs we derive a dependence of on latitude for b between -0.8^\circ and -2.8^\circ of -0.085 \pm 0.033 dex/degree. When combined with the data from Tiede et al. we find for -0.8^\circ \leq b \leq -10.3^\circ the slope in is -0.064 \pm 0.012 dex/degree. An extrapolation to the Galactic Center predicts [Fe/H] = +0.034 \pm 0.053 dex. We also derive average values for the extinction in the K band (A_K) of between 2.15 and 0.27 for the inner bulge fields corresponding to average values of E(J-K) of between 3.46 and 0.44. There is a well defined linear relation between the average extinction for a field and the star-to-star scatter in the extinction for the stars within each field. This result suggests that the typical apparent angular scale size for an absorbing cloud is small compared with the field size (90\arcsec on a side). Finally, from an examination of the luminosity function of bright giants in each field we conclude that the young component of the stellar population observed near the Galactic center declines in density much more quickly than the overall bulge population and is undetectable beyond 1^\circ from the Galactic center.Comment: accepted for publication in Astron. Jour. Compressed file contains the text, 9 figures, and 6 tables prepared with AAS Latex macros v. 4.