8,529 research outputs found
Crossover from diffusive to strongly localized regime in two-dimensional systems
We have studied the conductance distribution function of two-dimensional
disordered noninteracting systems in the crossover regime between the diffusive
and the localized phases. The distribution is entirely determined by the mean
conductance, g, in agreement with the strong version of the single-parameter
scaling hypothesis. The distribution seems to change drastically at a critical
value very close to one. For conductances larger than this critical value, the
distribution is roughly Gaussian while for smaller values it resembles a
log-normal distribution. The two distributions match at the critical point with
an often appreciable change in behavior. This matching implies a jump in the
first derivative of the distribution which does not seem to disappear as system
size increases. We have also studied 1/g corrections to the skewness to
quantify the deviation of the distribution from a Gaussian function in the
diffusive regime.Comment: 4 pages, 4 figure
The Zipf law for random texts with unequal probabilities of occurrence of letters and the Pascal pyramid
We model the generation of words with independent unequal probabilities of
occurrence of letters. We prove that the probability of occurrence of
words of rank has a power asymptotics. As distinct from the paper published
earlier by B. Conrad and M. Mitzenmacher, we give a brief proof by elementary
methods and obtain an explicit formula for the exponent of the power law.Comment: 4 page
Gene identification for the cblD defect of vitamin B12 metabolism
Background Vitamin B12 (cobalamin) is an essential cofactor in several metabolic pathways. Intracellular conversion of cobalamin to its two coenzymes, adenosylcobalamin in mitochondria and methylcobalamin in the cytoplasm, is necessary for the homeostasis of methylmalonic acid and homocysteine. Nine defects of intracellular cobalamin metabolism have been defined by means of somatic complementation analysis. One of these defects, the cblD defect, can cause isolated methylmalonic aciduria, isolated homocystinuria, or both. Affected persons present with multisystem clinical abnormalities, including developmental, hematologic, neurologic, and metabolic findings. The gene responsible for the cblD defect has not been identified.
Methods We studied seven patients with the cblD defect, and skin fibroblasts from each were investigated in cell culture. Microcell-mediated chromosome transfer and refined genetic mapping were used to localize the responsible gene. This gene was transfected into cblD fibroblasts to test for the rescue of adenosylcobalamin and methylcobalamin synthesis.
Results The cblD gene was localized to human chromosome 2q23.2, and a candidate gene, designated MMADHC (methylmalonic aciduria, cblD type, and homocystinuria), was identified in this region. Transfection of wild-type MMADHC rescued the cellular phenotype, and the functional importance of mutant alleles was shown by means of transfection with mutant constructs. The predicted MMADHC protein has sequence homology with a bacterial ATP-binding cassette transporter and contains a putative cobalamin binding motif and a putative mitochondrial targeting sequence.
Conclusions Mutations in a gene we designated MMADHC are responsible for the cblD defect in vitamin B12 metabolism. Various mutations are associated with each of the three biochemical phenotypes of the disorder
A two-dimensional, two-electron model atom in a laser pulse: exact treatment, single active electron-analysis, time-dependent density functional theory, classical calculations, and non-sequential ionization
Owing to its numerical simplicity, a two-dimensional two-electron model atom,
with each electron moving in one direction, is an ideal system to study
non-perturbatively a fully correlated atom exposed to a laser field. Frequently
made assumptions, such as the ``single active electron''- approach and
calculational approximations, e.g. time dependent density functional theory or
(semi-) classical techniques, can be tested. In this paper we examine the
multiphoton short pulse-regime. We observe ``non-sequential'' ionization, i.e.\
double ionization at lower field strengths as expected from a sequential,
single active electron-point of view. Since we find non-sequential ionization
also in purely classical simulations, we are able to clarify the mechanism
behind this effect in terms of single particle trajectories. PACS Number(s):
32.80.RmComment: 10 pages, 16 figures (gzipped postscript), see also
http://www.physik.tu-darmstadt.de/tqe
Jumps in current-voltage characteristics in disordered films
We argue that giant jumps of current at finite voltages observed in
disordered samples of InO, TiN and YSi manifest a bistability caused by the
overheating of electrons. One of the stable states is overheated and thus
low-resistive, while the other, high-resistive state is heated much less by the
same voltage. The bistability occurs provided that cooling of electrons is
inefficient and the temperature dependence of the equilibrium resistance, R(T),
is steep enough. We use experimental R(T) and assume phonon mechanism of the
cooling taking into account its strong suppression by disorder. Our description
of details of the I-V characteristics does not involve adjustable parameters
and turns out to be in a quantitative agreement with the experiments. We
propose experiments for more direct checks of this physical picture.Comment: Final version, as published; 4 pages, 3 figure
Ejection Energy of Photoelectrons in Strong Field Ionization
We show that zero ejection energy of the photoelectrons is classically
impossible for hydrogen-like ions, even when field ionization occurs
adiabatically. To prove this we transform the basic equations to those
describing two 2D anharmonic oscillators. The same method yields an alternative
way to derive the anomalous critical field of hydrogen-like ions. The
analytical results are confirmed and illustrated by numerical simulations. PACS
Number: 32.80.RmComment: 7 pages, REVTeX, postscript file including the figures is available
at http://www.physik.th-darmstadt.de/tqe/dieter/publist.html or via anonymous
ftp from ftp://tqe.iap.physik.th-darmstadt.de/pub/dieter/publ_I_pra_pre.ps,
accepted for publication in Phys. Rev.
Handbook of Life Course Health Development
This handbook synthesizes and analyzes the growing knowledge base on life course health development (LCHD) from the prenatal period through emerging adulthood, with implications for clinical practice and public health. It presents LCHD as an innovative field with a sound theoretical framework for understanding wellness and disease from a lifespan perspective, replacing previous medical, biopsychosocial, and early genomic models of health. Interdisciplinary chapters discuss major health concerns (diabetes, obesity), important less-studied conditions (hearing, kidney health), and large-scale issues (nutrition, adversity) from a lifespan viewpoint. In addition, chapters address methodological approaches and challenges by analyzing existing measures, studies, and surveys. The book concludes with the editors’ research agenda that proposes priorities for future LCHD research and its application to health care practice and health policy
Localization Length in Anderson Insulator with Kondo Impurities
The localization length, , in a 2--dimensional Anderson insulator
depends on the electron spin scattering rate by magnetic impurities,
. For antiferromagnetic sign of the exchange, %constant, the time
is {\em itself a function of }, due to the Kondo correlations. We
demonstrate that the unitary regime of localization is impossible when the
concentration of magnetic impurities, , is smaller than a critical
value, . For , the dependence of on the
dimensionless conductance, , is {\em reentrant}, crossing over to unitary,
and back to orthogonal behavior upon increasing . Sensitivity of Kondo
correlations to a weak {\em parallel} magnetic field results in a giant
parallel magnetoresistance.Comment: 5 pages, 1 figur
- …