386 research outputs found

    Direct and Indirect Complementarity between Workplace Reorganization and New Technology

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    We link survey and balance sheet data to investigate the extent of complementarity between the introduction of new technology and changes in workplace practices. Across all firms, we find that new technology is complementary with higher work intensity. Similarly, changes in work techniques yield diffuse complementarity gains, particularly in firms undergoing extensive restructuring. Changes in work organization yield, on average, complementarity gains in terms of productivity growth. Substitutability between new technology and specific workplace changes is sometimes found, consistently with the presence of costs associated to learning functions or resistance to changes.workplace practices, ICT investments, complementarity.

    Photon-number resolving detector based on a series array of superconducting nanowires

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    We present the experimental demonstration of a superconducting photon number resolving detector. It is based on the series connection of N superconducting nanowires, each connected in parallel to an integrated resistor. The device provides a single voltage readout, proportional to the number of photons absorbed in distinct nanowires. Clearly separated output levels corresponding to the detection of n=1-4 photons are observed in a 4-element detector fabricated from an NbN film on GaAs substrate, with a single-photon system quantum efficiency of 2.6% at the wavelength of 1300nm. The series-nanowire structure is promising in view of its scalability to large photon numbers and high efficiencies.Comment: 12 pages, 6 figure

    A new record of Craspedacusta sowerbii, Lankester 1880 (Cnidaria, Limnomedusae) in Northern Italy

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    A new record of the freshwater jellyfish Craspedacusta sowerbii in Northern Italy is reported. The medusae bloom occurred in a small oligo-mesotrophic artificial lake during July, 2009. At the time of sampling, the medusae were all immature, reached low density and showed feeding preference towards the Daphnia complex of species, the most abundant zooplanktonic species in the lake. Negative feeding selectivity towards small Rotifera was demonstrated. The occasional occurrence of a C. sowerbii bloom in this lake suggests the distribution range of this species may be largely underestimated, and its potential impact on the zooplankton community remains unknown

    Ultrasensitive N-photon interferometric autocorrelator

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    We demonstrate a novel method to measure the Nth-order (N=1, 2, 3, 4) interferometric autocorrelation with high sensitivity and temporal resolution. It is based on the combination of linear absorption and nonlinear detection in a superconducting nanodetector, providing much higher efficiency than methods based on all-optical nonlinearities. Its temporal resolution is only limited by the quasi-particle energy relaxation time, which is directly measured to be in the 20 ps range for the NbN films used in this work. We present a general model of interferometric autocorrelation with these nonlinear detectors and discuss the comparison with other approaches and possible improvements

    MicroRNAs delivery into human cells grown on 3D-printed PLA scaffolds coated with a novel fluorescent PAMAM dendrimer for biomedical applications

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    Many advanced synthetic, natural, degradable or non-degradable materials have been employed to create scaffolds for cell culture for biomedical or tissue engineering applications. One of the most versatile material is poly-lactide (PLA), commonly used as 3D printing filament. Manufacturing of multifunctional scaffolds with improved cell growth proliferation and able to deliver oligonucleotides represents an innovative strategy for controlled and localized gene modulation that hold great promise and could increase the number of applications in biomedicine. Here we report for the first time the synthesis of a novel Rhodamine derivative of a poly-amidoamine dendrimer (G = 5) able to transfect cells and to be monitored by confocal microscopy that we also employed to coat a 3D-printed PLA scaffold. The coating do not modify the oligonucleotide binding ability, toxicity or transfection properties of the scaffold that is able to increase cell proliferation and deliver miRNA mimics (i.e., pre-mir-503) into human cells. Although further experiments are required to optimize the dendrimer/miRNA ratio and improve transfection efficiency, we demonstrated the effectiveness of this promising and innovative 3D-printed transfection system to transfer miRNAs into human cells for future biomedical applications. © 2018, The Author(s)
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