Genome-Wide Linkage Analysis of Malaria Infection Intensity and Mild Disease

Although balancing selection with the sickle-cell trait and other red blood cell disorders has emphasized the interaction between malaria and human genetics, no systematic approach has so far been undertaken towards a comprehensive search for human genome variants influencing malaria. By screening 2,551 families in rural Ghana, West Africa, 108 nuclear families were identified who were exposed to hyperendemic malaria transmission and were homozygous wild-type for the established malaria resistance factors of hemoglobin (Hb)S, HbC, alpha(+) thalassemia, and glucose-6-phosphate-dehydrogenase deficiency. Of these families, 392 siblings aged 0.5–11 y were characterized for malaria susceptibility by closely monitoring parasite counts, malaria fever episodes, and anemia over 8 mo. An autosome-wide linkage analysis based on 10,000 single-nucleotide polymorphisms was conducted in 68 selected families including 241 siblings forming 330 sib pairs. Several regions were identified which showed evidence for linkage to the parasitological and clinical phenotypes studied, among them a prominent signal on Chromosome 10p15 obtained with malaria fever episodes (asymptotic z score = 4.37, empirical p-value = 4.0 × 10(−5), locus-specific heritability of 37.7%; 95% confidence interval, 15.7%–59.7%). The identification of genetic variants underlying the linkage signals may reveal as yet unrecognized pathways influencing human resistance to malaria

Comparison of Household Consumption and Regional Production Approaches to Assessing Urban Energy Use and Implications for Policy

Assessment of urban energy use may proceed by a number of methods. Here we derive an energy account from local statistics, and compare them with an input output (IO) analysis as applied to Melbourne, Australia. These approaches highlight different aspects of urban energy use and comparable outputs are presented together to assess consistency, to identify complementarities and discuss the insight each approach brings to understanding urban energy. The IO method captures the direct and embodied primary energy requirements of local household expenditure (235.8 GJ/capita/year) while the regional assessment more directly accounts for local production activity (258.1 GJ/capita/year). The parity of these results is unexpected for a developed city with a strong tertiary sector. Sectoral detail reveals differences between the primary energy required by Melbourne's economic structure and that ultimately required through the full supply chain relating to household expenditure. This is accompanied by an IO analysis of the geography of Melbourne's ‘energy catchment’. It is suggested that the IO consumption and regional production approaches have particular relevance to policies aimed at consumption behaviour and economic (re)structuring, respectively. Their complementarity further suggests that a combined analysis would be valuable in understanding urban energy futures and economic transitions elsewhere

IIT Reality - finding a Job as an IIT Grad (semester?), IPRO 333: IIT Reality - Finding a job as IIT Grad IPRO 333 Abstract Sp06

The objective of Ipro 333 is to create a documentary capturing the experience of IIT students trying to find a job after graduation. This is going to be done through a 3 semester process in which the group must plan, film, and edit footage taken. This being semester 2, the group goal is to finish the plans and all o f the filming, leaving only the very time consuming editing to the third semester.Deliverables for IPRO 333: IIT Reality - finding a Job as an IIT Grad for the Spring 2006 semeste

IIT Reality - finding a Job as an IIT Grad (semester?), IPRO 333

The objective of Ipro 333 is to create a documentary capturing the experience of IIT students trying to find a job after graduation. This is going to be done through a 3 semester process in which the group must plan, film, and edit footage taken. This being semester 2, the group goal is to finish the plans and all o f the filming, leaving only the very time consuming editing to the third semester.Deliverables for IPRO 333: IIT Reality - finding a Job as an IIT Grad for the Spring 2006 semeste

IIT Reality - finding a Job as an IIT Grad (semester?), IPRO 333: IIT Reality - Finding a job as IIT Grad IPRO 333 Poster Sp06

The objective of Ipro 333 is to create a documentary capturing the experience of IIT students trying to find a job after graduation. This is going to be done through a 3 semester process in which the group must plan, film, and edit footage taken. This being semester 2, the group goal is to finish the plans and all o f the filming, leaving only the very time consuming editing to the third semester.Deliverables for IPRO 333: IIT Reality - finding a Job as an IIT Grad for the Spring 2006 semeste

IIT Reality - finding a Job as an IIT Grad (semester?), IPRO 333: IIT Reality - Finding a job as IIT Grad IPRO 333 Project Plan Sp06

The objective of Ipro 333 is to create a documentary capturing the experience of IIT students trying to find a job after graduation. This is going to be done through a 3 semester process in which the group must plan, film, and edit footage taken. This being semester 2, the group goal is to finish the plans and all o f the filming, leaving only the very time consuming editing to the third semester.Deliverables for IPRO 333: IIT Reality - finding a Job as an IIT Grad for the Spring 2006 semeste

IIT Reality - finding a Job as an IIT Grad (semester?), IPRO 333: IIT Reality - Finding a job as IIT Grad IPRO 333 Final Report Sp06

The objective of Ipro 333 is to create a documentary capturing the experience of IIT students trying to find a job after graduation. This is going to be done through a 3 semester process in which the group must plan, film, and edit footage taken. This being semester 2, the group goal is to finish the plans and all o f the filming, leaving only the very time consuming editing to the third semester.Deliverables for IPRO 333: IIT Reality - finding a Job as an IIT Grad for the Spring 2006 semeste

The IIT Reality: Finding a Job (semester?), IPRO 333: IIT Reality - Finding a job as IIT Grad IPRO 333 Final Report F06

This semester IPRO 333, Video Documentary – Getting a Job after Graduation, is aiming its effort to help Illinois Institute of Technology Students get better jobs after graduation. This continuation of an earlier IPRO will strive to produce a video that presents four different challenges to be completed in the job seeking process. Students will work together in four “challenge” teams as well as three technical teams to accomplish its objective.Deliverables for IPRO 333: The IIT Reality - Finding a Job for the Fall 2006 semeste

The IIT Reality: Finding a Job (semester?), IPRO 333

This semester IPRO 333, Video Documentary – Getting a Job after Graduation, is aiming its effort to help Illinois Institute of Technology Students get better jobs after graduation. This continuation of an earlier IPRO will strive to produce a video that presents four different challenges to be completed in the job seeking process. Students will work together in four “challenge” teams as well as three technical teams to accomplish its objective.Deliverables for IPRO 333: The IIT Reality - Finding a Job for the Fall 2006 semeste