The suitability of a rolled BHK₂₁monolayer system for the production of vaccines against the SAT types of foot-and-mouth disease virus. I. Adaptation of virus isolates to the system, immunogen yields achieved and assessment of subtype cross reactivity

In an examination of 34 southern African SAT-type foot-and-mouth disease viruses, all but 1 attained satisfactory levels of infectivity within 6 passages in rolled BHK₂₁monolayer cell cultures. However, there were marked differences between adapted viruses with respect to the mass of immunogen (146S material) produced. Several isolates which consistently produced levels ≥2 µg/ml were identified. In cross neutralization tests using post-vaccinal sera, SAT-1 and SAT-2 isolates showed considerable diversity and none of the viruses tested would be expected to produce a broad-spectrum response if incorporated into a vaccine. On the other hand, when 2 of the SAT-2 isolates were incorporated into the same vaccine a distinctly broader response resulted.The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.lmchunu2014mn201

Irrigating with polyacrylamide (PAM) - Nine years and a million acres of experience

Polyacrylamide (PAM) has been available commercially since 1995 for reducing irrigation-induced erosion and enhancing infiltration. The first series of practical field tests was conducted in 1991. PAM used for erosion control is a large water soluble (non-crosslinked) anionic molecule (12-15 megagrams per mole) containing < 0.05% acrylamide monomer. In controlled field studies PAM eliminated, on average, 94% (80-99% range) of sediment loss in field runoff from furrow irrigation, with a typical 15-50% relative infiltration increase on medium to fine textured soils compared to untreated controls. Similar but less dramatic results have been seen with sprinkler irrigation. Under some conditions infiltration is unchanged or can even be slightly reduced, e.g. in sandy soils or where PAM application rates are very high. Results are achieved with per irrigation field application rates of about 1 kg per hectare, for furrow irrigation, and 2 to 4 kg per hectare for sprinkler irrigation. Cost of PAM is $7 to$13 per kg. Seasonal application totals vary from 3 to 7 kg per hectare. Farmer field sediment control has been around 80% of test plot results. Substantial runoff reductions have been documented for nutrients, pesticides, microorganisms, BOD, and weed seed. No adverse effects have been seen for soil microbial populations. Crop yields have not been widely documented, though evidence exists for yield increases related to infiltration improvement. High effectiveness, low cost, and ease of application, compared to traditional conservation measures, has resulted in rapid technology acceptance in the US and internationally. PAM-use for runoff water quality protection is one of the most potent new irrigation environmental technologies in the market place. New uses in construction and dryland erosion control are being developed rapidly. This paper discusses new insights and understanding of PAM-use and potential for future development

Classification of Supernovae

The current classification scheme for supernovae is presented. The main observational features of the supernova types are described and the physical implications briefly addressed. Differences between the homogeneous thermonuclear type Ia and similarities among the heterogeneous core collapse type Ib, Ic and II are highlighted. Transforming type IIb, narrow line type IIn, supernovae associated with GRBs and few peculiar objects are also discussed.Comment: 16 Pages, 4 figures, to be published in "Supernovae and Gamma-Ray Bursters," ed. Kurt W. Weile

Catching Element Formation In The Act ; The Case for a New MeV Gamma-Ray Mission: Radionuclide Astronomy in the 2020s

High Energy Astrophysic

Homocysteine and its disulfide derivatives: a suggested consensus terminology.

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