467 research outputs found

    Etude de l'impact sur pale d'hélicoptÚre

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    Le prĂ©sent article propose une Ă©tude de l’endommagement de structures similaires Ă  des tronçons de pales d’hĂ©licoptĂšre soumises Ă  un impact. Il s’agit de structures composites complexes, fabriquĂ©es au laboratoire, et impactĂ©es par un projectile de 125 g Ă  des vitesses d’impact de 130 m/s. Les essais sont analysĂ©s grĂące Ă  une acquisition des dĂ©formations au cours de l’essai et Ă  une expertise post-mortem de l’éprouvette. Cela a permis de mettre en Ă©vidence les diffĂ©rents mĂ©canismes d'endommagement de l'Ă©prouvette. Un travail de modĂ©lisation est aussi prĂ©sentĂ©. DiffĂ©rentes stratĂ©gies de modĂ©lisation sous Ă©lĂ©ments finis, Ă  l’échelle macroscopique, permettent ainsi de modĂ©liser ces phĂ©nomĂšnes avec des densitĂ©s de maillage qui ne sont pas pĂ©nalisantes lors d'un calcul sur une structure rĂ©elle

    Sequential difficulty effects in cognitive and sensorimotor tasks: Insights from arithmetic and Fitts' task

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    International audienceThe present study tested sequential difficulty effects (SDEs) in arithmetic problem solving and Fitts’ aiming task for the same individuals. SDEs refer to poorer performance on current items following harder items relative to after easier items. Young and older adults accomplished a computational estimation task (i.e., finding the approximate products to two digit multiplication problems) and a Fitts aiming task (i.e., performing rapid pointing movements to reach the finish areas). Current items were preceded by two easy or difficult items (i.e., in the repeate precursor condition) or only one easy or difficult item (i.e., in the unrepeated precursor condition). Participants’ performance revealed SDEs in both the arithmetic and the aiming tasks only when the precursor items were repeated. Data also revealed comparable SDEs in both age groups during the arithmetic task, but SDEs only in older adults while participants accomplished the aiming task. These findings have a number of implications for our understanding of mechanisms underlying SDEs and age-related differences in SDEs, as they suggest that SDEs involve both domain general and domain specific mechanisms that are differentially influenced by aging

    Advanced Neuroimaging with Computed Tomography Scanning

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    International audienceThe x-ray computed tomography (CT) is well known as a useful imaging method and thus CT images have continuingly been used for many applications, especially in medical fields. This book discloses recent advances and new ideas in theories and applications for CT imaging and its analysis. The 16 chapters selected in this book cover not only the major topics of CT imaging and analysis in medical fields, but also some advanced applications for forensic and industrial purposes. These chapters propose state-of-the-art approaches and cutting-edge research results

    Catastrophe Survived? The Failure of the Tragic in Moira Buffini'sWelcome to Thebes

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    In Moira Buffini's Welcome to Thebes (2010) Antigone fails to reach her tragic destiny, the city of Thebes fails to become an autonomous democratic state, and the audience fails to witness the splendour of the ancient heroine. In this paper I consider these three failures as interrelated and dependent upon one another, arguing, along psychoanalytic lines, that they register changing attitudes towards knowledge and the Other which ultimately determine the meaning of ‘failure’. However, in order to better appreciate the contemporary scope of failure, I draw on both Lacan and Baudrillard, highlighting convergences between the two theorists. In particular, I argue that Lacan's notion of the inconsistent Other can be supplemented by Baudrillard's notion of the impossible exchange. Further, the relevance of these notions for theatre and spectatorship is discussed in detail, as they both invite spectators to reflect on their own involvement in the scene they witness and the ontological conditions of (their own) absence and presence. Failure to do so possibly indicates an irreparable loss of the critical capacity which we have always considered central to radical thought

    Early Deformation of Deep Brain Stimulation Electrodes Following Surgical Implantation: Intracranial, Brain, and Electrode Mechanics

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    IntroductionAlthough deep brain stimulation is nowadays performed worldwide, the biomechanical aspects of electrode implantation received little attention, mainly as physicians focused on the medical aspects, such as the optimal indication of the surgical procedure, the positive and adverse effects, and the long-term follow-up. We aimed to describe electrode deformations and brain shift immediately after implantation, as it may highlight our comprehension of intracranial and intracerebral mechanics.Materials and MethodsSixty electrodes of 30 patients suffering from severe symptoms of Parkinson’s disease and essential tremor were studied. They consisted of 30 non-directional electrodes and 30 directional electrodes, implanted 42 times in the subthalamus and 18 times in the ventrolateral thalamus. We computed the x (transversal), y (anteroposterior), z (depth), torsion, and curvature deformations, along the electrodes from the entrance point in the braincase. The electrodes were modelized from the immediate postoperative CT scan using automatic voxel thresholding segmentation, manual subtraction of artifacts, and automatic skeletonization. The deformation parameters were computed from the curve of electrodes using a third-order polynomial regression. We studied these deformations according to the type of electrodes, the clinical parameters, the surgical-related accuracy, the brain shift, the hemisphere and three tissue layers, the gyration layer, the white matter stem layer, and the deep brain layer (type I error set at 5%).ResultsWe found that the implanted first hemisphere coupled to the brain shift and the stiffness of the type of electrode impacted on the electrode deformations. The deformations were also different according to the tissue layers, to the electrode type, and to the first-hemisphere-brain-shift effect.ConclusionOur findings provide information on the intracranial and brain biomechanics and should help further developments on intracerebral electrode design and surgical issues

    Cytopathic effects of the cytomegalovirus-encoded apoptosis inhibitory protein vMIA

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    Replication of human cytomegalovirus (CMV) requires the expression of the viral mitochondria–localized inhibitor of apoptosis (vMIA). vMIA inhibits apoptosis by recruiting Bax to mitochondria, resulting in its neutralization. We show that vMIA decreases cell size, reduces actin polymerization, and induces cell rounding. As compared with vMIA-expressing CMV, vMIA-deficient CMV, which replicates in fibroblasts expressing the adenoviral apoptosis suppressor E1B19K, induces less cytopathic effects. These vMIA effects can be separated from its cell death–inhibitory function because vMIA modulates cellular morphology in Bax-deficient cells. Expression of vMIA coincided with a reduction in the cellular adenosine triphosphate (ATP) level. vMIA selectively inhibited one component of the ATP synthasome, namely, the mitochondrial phosphate carrier. Exposure of cells to inhibitors of oxidative phosphorylation produced similar effects, such as an ATP level reduced by 30%, smaller cell size, and deficient actin polymerization. Similarly, knockdown of the phosphate carrier reduced cell size. Our data suggest that the cytopathic effect of CMV can be explained by vMIA effects on mitochondrial bioenergetics

    Search for CP Violation in the Decay Z -> b (b bar) g

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    About three million hadronic decays of the Z collected by ALEPH in the years 1991-1994 are used to search for anomalous CP violation beyond the Standard Model in the decay Z -> b \bar{b} g. The study is performed by analyzing angular correlations between the two quarks and the gluon in three-jet events and by measuring the differential two-jet rate. No signal of CP violation is found. For the combinations of anomalous CP violating couplings, h^b=h^AbgVb−h^VbgAb{\hat{h}}_b = {\hat{h}}_{Ab}g_{Vb}-{\hat{h}}_{Vb}g_{Ab} and hb∗=h^Vb2+h^Ab2h^{\ast}_b = \sqrt{\hat{h}_{Vb}^{2}+\hat{h}_{Ab}^{2}}, limits of \hat{h}_b < 0.59and and h^{\ast}_{b} < 3.02$ are given at 95\% CL.Comment: 8 pages, 1 postscript figure, uses here.sty, epsfig.st
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