57 research outputs found
Value Conflict, Lack of Rewards, and Sense of Community as Psychosocial Risk Factors of Burnout in Communication Professionals (Press, Radio, and Television)
Journalists are at particular risk of work-related stress and burnout. The objective of this study is to describe and analyze the principal factors involved in the appearance of burnout in communication professionals, as well as the possible interactions between them and with self-reported health, and to observe whether the variables involved are the same in different types of environments. To achieve this objective, 292 participants answered the following measurement instruments: Demographic and labor datasheet; Maslach Burnout Inventory (MBI General survey); Areas of Worklife Scale (AWS); and General Health Questionnaire (GHQ -12). The results were the following: Emotional Exhaustion (EE) shows direct correlation and statistical significance with the other two burnout dimensions, Depersonalization (DP) and Personal Accomplishment (PA), also with health perception variables and inverse and statistical significance with the workload, control, rewards, community, fairness, and values. A multiple linear regression model shows workload and values as inverse EE predictors, which confirms a burnout process in which EE contributes as the main dimension in DP and is shown to be a precursor of PA, itself. When comparing different types of media, journalists who work in institutional press offices presented significantly lower scores in PA and higher in control, rewards, community, justice, and values. Therefore, further research should be carried out in order to analyze the protective role of these variables regarding PA and burnout
Dapagliflozin and cardiovascular outcomes in type 2 diabetes
BACKGROUND
The cardiovascular safety profile of dapagliflozin, a selective inhibitor of sodium–
glucose cotransporter 2 that promotes glucosuria in patients with type 2 diabetes,
is undefined.
METHODS
We randomly assigned patients with type 2 diabetes who had or were at risk for atherosclerotic cardiovascular disease to receive either dapagliflozin or placebo. The primary safety outcome was a composite of major adverse cardiovascular events (MACE),
defined as cardiovascular death, myocardial infarction, or ischemic stroke. The primary efficacy outcomes were MACE and a composite of cardiovascular death or hospitalization for heart failure. Secondary efficacy outcomes were a renal composite
(≥40% decrease in estimated glomerular filtration rate to <60 ml per minute per
1.73 m2
of body-surface area, new end-stage renal disease, or death from renal or
cardiovascular causes) and death from any cause.
RESULTS
We evaluated 17,160 patients, including 10,186 without atherosclerotic cardiovascular
disease, who were followed for a median of 4.2 years. In the primary safety outcome
analysis, dapagliflozin met the prespecified criterion for noninferiority to placebo with
respect to MACE (upper boundary of the 95% confidence interval [CI], <1.3; P<0.001
for noninferiority). In the two primary efficacy analyses, dapagliflozin did not result
in a lower rate of MACE (8.8% in the dapagliflozin group and 9.4% in the placebo
group; hazard ratio, 0.93; 95% CI, 0.84 to 1.03; P=0.17) but did result in a lower rate
of cardiovascular death or hospitalization for heart failure (4.9% vs. 5.8%; hazard
ratio, 0.83; 95% CI, 0.73 to 0.95; P=0.005), which reflected a lower rate of hospitalization for heart failure (hazard ratio, 0.73; 95% CI, 0.61 to 0.88); there was no
between-group difference in cardiovascular death (hazard ratio, 0.98; 95% CI, 0.82 to
1.17). A renal event occurred in 4.3% in the dapagliflozin group and in 5.6% in the
placebo group (hazard ratio, 0.76; 95% CI, 0.67 to 0.87), and death from any cause
occurred in 6.2% and 6.6%, respectively (hazard ratio, 0.93; 95% CI, 0.82 to 1.04). Diabetic ketoacidosis was more common with dapagliflozin than with placebo (0.3%
vs. 0.1%, P=0.02), as was the rate of genital infections that led to discontinuation of the
regimen or that were considered to be serious adverse events (0.9% vs. 0.1%, P<0.001).
CONCLUSIONS
In patients with type 2 diabetes who had or were at risk for atherosclerotic cardiovascular disease, treatment with dapagliflozin did not result in a higher or lower rate
of MACE than placebo but did result in a lower rate of cardiovascular death or hospitalization for heart failure, a finding that reflects a lower rate of hospitalization
for heart failure. (Funded by AstraZeneca; DECLARE–TIMI 58 ClinicalTrials.gov
number, NCT01730534.
Job burnout
Synthèse de 25 ans de recherches sur l'épuisement et la lassitude professionnels : ses divers aspects ; ses causes : nature et organisation du travail ; les facteurs individuels ; les interventions sur l'individu et sur la situation de travail
(Eds.). Engagement at work: An emerging concept [spec. iss.]
Contains fulltext :
73648.pdf (publisher's version ) (Closed access)110 p
Work engagement: An emerging concept in occupational health psychology
Contains fulltext :
73301.pdf (publisher's version ) (Closed access
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