Review: Disease risk analysis of importing animals and livestock products.

International audience20 Gbit/s time/polarisation multiplexed solitons have been transmitted over 10 Mm in a recirculating loop with a 63 km amplification span using the sliding-frequency guiding filter soliton control technique. The soliton energy, sliding rate, filter bandwidth and wavelength margins for a BER of 10-9 have been measured at 6 M

Utilité d'une loi sur l'exercice de la souveraineté nationale, par Pierre Le Guen,...

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De la Patience en politique, par M. Leguen,...

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Extrusion 3D Printing of Polybutyrate-Adipate-Terephthalate-Polymer Composites in the Pellet Form

Fused deposition modelling is a common 3D printing technique used for the freeform fabrication of complex shapes based on polymers. Acrylonitrile butadiene styrene (ABS) is the common material option, though polylactide (PLA) has also proved to be a successful candidate. There is an ever increasing demand to harness new materials as possible candidates for fused deposition. The current research is focused on evaluating polybutyrate-adipate-terephthalate–polymer (PBAT) for fused deposition modelling. Both neat and composite PBAT filled with varying wood flour fillers were experimentally analyzed for 3D printing by extrusion from the pellet forms. The results are positive and the addition of small quantities of the wood flour filler material was found to improve the thixotropic nature of the polymer composite and consequently the inter-strand and inter-layer coalescence

DNA damage at the dawn of micro-RNA pathway impairment in pulmonary arterial hypertension: DOI: 10.14800/rd.810

Over the last years, small non-coding microRNAs (miRNAs) have emerged as central actors of PAH etiology. Strong miRNA expression disorders occur in lungs as well as in right ventricle (RV) of PAH patients, which respectively lead to vascular remodeling of the distal pulmonary arteries and to RV failure. On the other hand, our understanding of PAH physiopathology has recently increased with the implication of DNA damage and DNA damage response (DDR) in this disease. Interestingly, DDR was described as a regulator of miRNA processing in both healthy and pathological conditions. In this review, we will first summarize miRNA expression impaired in lung and RV of PAH patients, then we will provide evidence that DDR could be at origin of miRNA pathway defects observed in pulmonary hypertension

40 Gbit/s, 5×100 km span straight line soliton transmission experiment without in-line control

International audienceA straight line single wavelength 40 Gbit/s soliton transmission experiment was conducted over five spans of 100 km DS fibre without in-line control. The 10 ps pulse train generated at 20 GHz using an EA modulator was encoded at 70 Gbit/s and multiplexed at 40 Gbit/s in the polarisation and time domain. Demultiplexing from 40 to 10 Gbit/s was performed using a polariser and an EAM successively. A BER <10-10 was obtained over >4 dB inline power variations

Global assessment of the response to chronic stress in European sea bass

Stress modifies energy allocation in fishes by redirecting energy from growth and reproduction to coping mechanisms. However, these adjustments become inappropriate when the challenge consists of sustained or repeated stressors, with the animal entering a maladaptive state. Capacities to cope with additional threats are then altered and compromise survival. The characterization of the responses to chronic stress in fishes helps better understanding the physiological limits in an aquaculture or ecological context. Here, we investigate the coping capacities of European sea bass to multiple and diverse stressors applied over a 3-weeks period. Multiple behavioural (group dispersion and swimming activity) and physiological responses (blood cortisol, osmoregulatory mechanisms, stress-related gene expression, etc.) were evaluated in resting fish or in fish exposed to additional challenges. Resilience to the chronic stress protocol was evaluated 4 months after the end of the chronic stress. Chronically stressed individuals showed reduced growth, lower cortisol response, increased chloride and sodium concentration in the plasma and modified gill gene expression translating osmoregulatory dysfunctions. Chronic stress had no significant effect on plasmatic calcium, lysozyme concentration and osmotic pressure. Increased thigmotaxic behaviour was observed in a new environment behavioural test. Four months after the chronic stress, no significant difference was observed in growth performances and in plasma parameters. Altogether, gills and more generally osmoregulatory functions were found to be the most sensitive to the chronic stress, while only limited changes in growth, activity of the HPI axis, immunity and swimming behaviour were observed when assessed individually. This work demonstrates the necessity of using multiple and diverse endpoints related to different functions to properly assess health and welfare in fishes

Comparison of global analysis technique and direct evaluation of capsizing probability on French frigates

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Single-wavelength 40 Gbit/s, 8×100 km-span soliton transmission without any in-line control.

International audienceA straight-line single-wavelength 40 Gbit/s soliton transmission experiment was conducted over eight spans of 100 km DS fibre without in-line control nor local dispersion management. Q2-factors of >17 dB were measured at 800 km for two extreme cases of dispersion map over each amplifier span. Power margins of 3 dB at Q2>16.2 dB (BER<10-10) were obtained over a 1 nm wavelength-range