Прогностическое значение аспиринорезистентности при ишемической болезни сердца

Рассмотрены данные литературы о значении аспиринорезистентности при ИБС. Предложен разработанный авторами новый экспресс−метод определения чувствительности к аспирину. Показана роль аспиринорезистентности в развитии сердечно−сосудистых событий у больных.The literature data about the role of aspirin resistance in coronary artery disease are discussed. The original new express method of determining sensitivity to aspirin is suggested. The role of aspirin resistance in development of cardiovascular events in the patients is shown

Inhibition, friend or foe? Cognitive inhibition as a moderator between mathematical ability and mathematical creativity in primary school students

It is still unclear which cognitive factors stand at the base of mathematical creativity. One factor could be inhibition, but results are inconsistent. A possible explanation is that this relation is more complex than the direct relations tested, until now. In the current study, the hypothesis was tested that cognitive inhibition moderated the relationship between mathematical ability and mathematical creativity. The sample included 82 primary school students between 8 and 12 years of age. Mathematical creativity was measured with a multiple solution task and scored on fluency, flexibility, and originality. While there was a direct relation between mathematical ability and mathematical creativity, inhibition did not have a direct effect on mathematical creativity, but it positively moderated this relationship for flexibility and originality. These results indicate that reduced inhibition strengthens the relationship between mathematical ability and mathematical flexibility and between mathematical ability and mathematical originality, but not the relation between mathematical ability and mathematical fluency. These findings are discussed in relation to children with high and low mathematical abilities, measurement of inhibition, and the domain-general/domain-specific discussion of creativity

Effects of remedial numeracy instruction throughout kindergarten starting at different ages: Evidence from a large-scale longitudinal study

The aims of this study are to investigate the effects of remedial numeracy support throughout kindergarten, and to compare the effects of interventions from different lengths. Support occurred two times per week for either 1.5 (90 sessions: complete condition) or 0.5 school years (28 sessions: short condition). Below-average students were randomly assigned to complete intervention ( N=155), short intervention ( N=105), or control (systematically offered education-as-usual; N=150). Accounting for achievements at pretest, children who received one of the interventions outperformed the control children in early numeracy at post-test and follow-up, suggesting that children internalized the learned knowledge. Transfer effects on simple arithmetic were only found in the complete support group, whereas both interventions were effective for complex mathematics

Counting and Number Line Trainings in Kindergarten: Effects on Arithmetic Performance and Number Sense

Children’s early numerical capacities form the building blocks for later arithmetic proficiency. Linear number placements and counting skills are indicative of mapping, as an important precursor to arithmetic skills, and have been suggested to be of vital importance to arithmetic development. The current study investigated whether fostering mapping skills is more efficient through a counting or a number line training program. Effects of both programs were compared through a quasi-experimental design, and moderation effects of age and socio-economic status (SES) were investigated. Ninety kindergartners were divided into three conditions: a counting, a number line, and a control condition. Pretests and posttests included an arithmetic (addition) task and a battery of number sense tasks (comparison, number lines, and counting). Results showed significantly greater gains in arithmetic, counting, and symbolic number lines in the counting training group than in the control group. The number line training group did not make significantly greater gains than the control group. Training gains were moderated by age, but not SES. We concluded that counting training improved numerical capacities effectively, whereas no such improvements could be found for the number line training. This suggests that only a counting approach is effective for fostering number sense and early arithmetic skills in kindergarten. Future research should elaborate on the parameters of training programs and the consequences of variation in these parameters

Verwonderd overdenken. Hoe moeilijk kan rekenen zijn?

Rede ter gelegenheid van het afscheid als hoogleraar Orthopedagogiek met als leeropdracht ‘Diagnostiek en behandeling van kinderen met dyscalculie’ aan de Universiteit Utrech

The contribution of executive functions in predicting mathematic creativity in typical elementary school classes: A twofold role for updating

The goal of the current study was to investigate the role of executive functions in mathematical creativity. The sample included 278 primary school children (ages 8–13). Two models were compared: the starting model tested whether executive functions (shifting, updating, and inhibition), domain-general creativity, and mathematical ability directly predicted mathematical creativity. The second model, which fitted the data best, included the additional assumption that updating influences mathematical creativity indirectly through mathematical ability and domain-general creativity. Updating was positively related to mathematical creativity. Additionally, updating was positively related to mathematical ability and domain-general creativity. Inhibition, shifting, domain-general creativity and mathematical ability did not have a significant contribution to either model but did positively correlate with mathematical creativity. This study reports the first empirical evidence that updating is a predictor of mathematical creativity in primary school children and demonstrates that creativity is a higher order cognitive process, activating a variety of cognitive abilities

Sex differences in the association of math achievement with visual-spatial and verbal working memory: Does the type of math test matter?

Previous research on sex differences in mathematical achievement shows mixed findings, which have been argued to depend on types of math tests used and the type of solution strategies (i.e., verbal versus visual-spatial) these tests evoke. The current study evaluated sex differences in (a) performance (development) on two types of math tests in primary schools and (b) the predictive value of verbal and visual-spatial working memory on math achievement. Children (N = 3175) from grades 2 through five participated. Visual-spatial and verbal working memory were assessed using online computerized tasks. Math performance was assessed five times during two school years using a speeded arithmetic test (math fluency) and a word problem test (math problem solving). Results from Multilevel Multigroup Latent Growth Modeling, showed that sex differences in level and growth of math performance were mixed and very small. Sex differences in the predictive value of verbal and visual-spatial working memory for math performance suggested that boys seemed to rely more on verbal strategies than girls. Explanations focus on cognitive and emotional factors and how these may interact to possibly amplify sex differences as children grow older

Longitudinal development of number line estimation and mathematics performance in primary school children

Children’s ability to relate number to a continuous quantity abstraction visualized as a number line is widely accepted to be predictive of mathematics achievement. However, a debate has emerged with respect to how children’s placements are distributed on this number line across development. In the current study, different models were applied to children’s longitudinal number placement data to get more insight into the development of number line representations in kindergarten and early primary school years. In addition, longitudinal developmental relations between number line placements and mathematical achievement, measured with a national test of mathematics, were investigated using cross-lagged panel modeling. A group of 442 children participated in a 3-year longitudinal study (ages 5–8 years) in which they completed a number-to-position task every 6 months. Individual number line placements were fitted to various models, of which a one-anchor power model provided the best fit for many of the placements at a younger age (5 or 6 years) and a two-anchor power model provided better fit for many of the children at an older age (7 or 8 years). The number of children who made linear placement

The effects of computer-based virtual learning environments on nursing students’ mathematical learning in medication processes

Computer-based virtual learning environments (CBVLEs) are potentially useful teaching tools for training nursing students in professional duties such as the mathematical tasks associated with medication processes. In this study, a CBVLE was designed with well-structured instructional activities such as interleaved practice and feedback. Mathematical medication scenarios and basic arithmetic exercises were integrated into the CBVLE. Four training conditions were used in the CBVLE to facilitate extra support for mathematical medication learning: (1) learning without worked examples, (2) learning with worked examples involving domain-specific knowledge, (3) learning with worked examples involving regular thinking strategies, and (4) learning with combined worked examples. This study was conducted with 118 nursing students enrolled in post-secondary nursing education and Bachelor’s nursing programmes. Students were pre-tested and post-tested on their mathematical medication learning. Training in the CBVLE improved mathematical medication learning for all students from pre-test to the post-test stages, but no differences were found among the four different conditions. Nursing students’ prior knowledge, non-verbal intelligence, and number of correct tasks predicted mathematical medication learning outcomes. When controlling for non-verbal intelligence, students in the condition 1 benefited more than students in condition 3 in terms of their mathematical medication learning outcomes. The same accounted for the support of the low-achieving students in the CBVLE. The support conditions for the high-achieving group appeared to be unimportant for mathematical medication learning. It seems that technology is taken over some of the capacity of working memory, which accounts for the benefits to the low-achieving learners