14 research outputs found
Effect of Adrenocorticotropic Hormone (ACTH) and Cortisone on the Several Varieties of Pemphigus1
- Author
- Publication venue
- The Williams and Wilkins Co. Published by Elsevier Inc.
- Publication date
- 31/08/1951
- Field of study
Oral and vocal fold diadochokinesis in dysphonic women
- Author
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease
- Author
- Aaltonen M
- Abdur Rahman M
- Abell T
- Abide W. Jr
- Acheatel R
- Achiri P
- Acon J
- Adams T
- Affinito S
- Agarwal S
- Aggarwal K
- Aggarwal R
- Ahlström P
- Ahmad A
- Ahmed M
- Aillon C
- Airaksinen A
- Ait-sadi R
- Akers J
- Al-jumaily J
- Albers C
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- Alberti A
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- Alford C
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- Allen T
- Allworth M
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- Aloisi A
- Alternburg C
- Alton M
- Amin J
- Amundson A
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- Andresen D
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- Zhao L
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- Zhou Yingyuan
- Zhu Wangqin
- Zhu X
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- Zineldine A
- Zlatewa R
- Zoghbi J
- Zong C
- Zong D
- Zong X
- Zuchelkowski A
- Zulauf N
- Ågårdh A
- Öner A
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2017
- Field of study
BACKGROUND:
Patients with atherosclerotic vascular disease remain at high risk for cardiovascular events despite effective statin-based treatment of low-density lipoprotein (LDL) cholesterol levels. The inhibition of cholesteryl ester transfer protein (CETP) by anacetrapib reduces LDL cholesterol levels and increases high-density lipoprotein (HDL) cholesterol levels. However, trials of other CETP inhibitors have shown neutral or adverse effects on cardiovascular outcomes.
METHODS:
We conducted a randomized, double-blind, placebo-controlled trial involving 30,449 adults with atherosclerotic vascular disease who were receiving intensive atorvastatin therapy and who had a mean LDL cholesterol level of 61 mg per deciliter (1.58 mmol per liter), a mean non-HDL cholesterol level of 92 mg per deciliter (2.38 mmol per liter), and a mean HDL cholesterol level of 40 mg per deciliter (1.03 mmol per liter). The patients were assigned to receive either 100 mg of anacetrapib once daily (15,225 patients) or matching placebo (15,224 patients). The primary outcome was the first major coronary event, a composite of coronary death, myocardial infarction, or coronary revascularization.
RESULTS:
During the median follow-up period of 4.1 years, the primary outcome occurred in significantly fewer patients in the anacetrapib group than in the placebo group (1640 of 15,225 patients [10.8%] vs. 1803 of 15,224 patients [11.8%]; rate ratio, 0.91; 95% confidence interval, 0.85 to 0.97; P=0.004). The relative difference in risk was similar across multiple prespecified subgroups. At the trial midpoint, the mean level of HDL cholesterol was higher by 43 mg per deciliter (1.12 mmol per liter) in the anacetrapib group than in the placebo group (a relative difference of 104%), and the mean level of non-HDL cholesterol was lower by 17 mg per deciliter (0.44 mmol per liter), a relative difference of -18%. There were no significant between-group differences in the risk of death, cancer, or other serious adverse events.
CONCLUSIONS:
Among patients with atherosclerotic vascular disease who were receiving intensive statin therapy, the use of anacetrapib resulted in a lower incidence of major coronary events than the use of placebo. (Funded by Merck and others; Current Controlled Trials number, ISRCTN48678192 ; ClinicalTrials.gov number, NCT01252953 ; and EudraCT number, 2010-023467-18 .)
Effect of Adrenocorticotropic Hormone (ACTH) and Cortisone on the Several Varieties of Pemphigus1
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
A Description of Phonetic, Acoustic, and Physiological Changes Associated With Improved Intelligibility in a Speaker With Spastic Dysarthria
- Author
- Abbs J. H.
- Ackerman H.
- Darley F. L.
- Delorey R.
- Duffy J. R.
- Dworkin J. P.
- Dworkin J. P.
- Dworkin J. P.
- Forrest K.
- Herbert A. Leeper
- Hirose H.
- Kent R. D.
- Kent R. D.
- Leeper H. A.
- Linebaugh C. W.
- Michael Blomgren
- Murdoch B. E.
- Nearey T.
- Nelson Roy
- Orlikoff R. F.
- Peterson G. E.
- Renout K. A.
- Rosalea M. Cameron
- Turner G. S.
- Weismer G.
- Weismer G.
- Weiss C. E.
- Weiss C. E.
- Yorkston K. M.
- Ziegler W.
- Publication venue
- 'American Speech Language Hearing Association'
- Publication date
- Field of study
Amino acid function and docking site prediction through combining disease variants, structure alignments, sequence alignments, and molecular dynamics: a study of the HMG domain
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
A Model of the International Monetary System
- Author
- A Spence
- Adrien Verdelhan
- Agust�n S B�n�trix
- Alan Moreira
- Andrei Shleifer
- Arvind Krishnamurthy
- B Taub
- Barry Eichengreen
- Barry Eichengreen
- Barry Eichengreen
- Barry Eichengreen
- Barry Eichengreen
- Ben Bemanke
- Ben Bernanke
- Benjamin Klein
- Christopher A Sims
- Christopher Bach
- Cristina Arellano
- Douglas W Diamond
- E Despres
- E Despres
- Eggertsson
- Emmanuel Farhi
- Emmanuel Farhi
- Emmanuel Farhi
- Enrique G Mendoza
- Eric M Leeper
- Fritz Machlup
- Fritz Machlup
- G Eggertsson
- Gary B Gorton
- Gary Gorton
- Gary Gorton
- Gita Gopinath
- Gita Gopinath
- Guillermo A Calvo
- Harold L Cole
- Hassan
- Helmut A Hagemann
- J M Keynes
- J M Keynes
- Jacques Rueff
- Jacques Rueff
- James E Meade
- James E Meade
- James Tobin
- Jeremy C Stein
- Jonathan Eaton
- Kiminori Matsuyama
- Livia Chitu
- M Obstfeld
- Marina Azzimonti
- Mark Aguiar
- Mark Gertler
- Matteo Maggiori
- Matteo Maggiori
- Matteo Maggiori
- Maurice Obstfeld
- Maurice Obstfeld
- Michael Woodford
- Milton Friedman
- Nicola Gennaioli
- Nicola Gennaioli
- Oliver Hart
- Olivier
- Olivier Accominotti
- Peter B Kenen
- Peter B Kenen
- Peter B Kenen
- Peter H Lindert
- Pierre-Olivier Gourinchas
- Pierre-Olivier Gourinchas
- Pierre-Olivier Gourinchas
- Rafael Repullo
- Ragnar Nurkse
- Ramon Marimon
- Rebecca S Demsetz
- Ricardo J Caballero
- Ricardo J Caballero
- Ricardo J Caballero
- Ricardo J Caballero
- Richard N Cooper
- Richard N Cooper
- Robert Triffin
- Robert Z Aliber
- Robert Z Aliber
- Robin Greenwood
- Roy Harrod
- Roy Harrod
- Tarek A Hassan
- Thomas J Sargent
- Valentina Bruno
- Wenxin Du
- William H Branson
- Xavier Gabaix
- Zhiguo He
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2016
- Field of study
Treatment Efficacy
- Author
- Allen K. D.
- Andrews M.
- Andrews M.
- Andrews S.
- Aronson A.
- Aronson A. E.
- Baker D. C.
- Barlow D. H.
- Baynes R. A.
- Bennett C. W.
- Berger M.
- Blager F. B.
- Blitzer A.
- Blitzer A.
- Bloch C. S.
- Bloch C. S.
- Boone D.
- Boone D.
- Bravendar P.
- Brayfield A. H.
- Brewer D. W.
- Bridger M. W.
- Brodnitz F. S.
- Brodnitz F. S.
- Brown W.
- Butcher P.
- Butcher P.
- Campbell D.
- Case J.
- Chan R. W. K.
- Christopher K. L.
- Cohen J.
- Colton R.
- Cooper M.
- Cooper M.
- Countryman S.
- Countryman S.
- Countryman S.
- Dedo H.
- Drudge M. K.
- Elias A.
- Erdman S.
- Fawcus M.
- Fitzgerald F.
- Flynn P. T.
- Ford C. N.
- Friedhoff A. J.
- Froeschels E.
- Gibson D. L.
- Gould W.
- Green M. C.
- Hammarberg B.
- Harrison G.
- Haywood A.
- Hillman R.
- Hoehn M.
- Holinger P.H.
- Horsley I.
- Hull F. M.
- H’etu R.
- Johnson J. A.
- Johnson T. S.
- Johnson T. S.
- Johnson T. S.
- Kaplan S.
- Katherine Verdolini
- Kay N.
- Kazdin A.
- Koufman J.
- Koufman J.
- Koufman J.
- Koufman J.
- Koufman J.
- Kratochwill T.
- Lancer J. M.
- Lanwehr L. P.
- Lass N.
- Leeper H.
- Leske M. C.
- Logemann J. A.
- Lorraine Olson Ramig
- Martin R. J.
- Martin S.
- Mathieson L.
- McFarlane S.
- McFarlane S.
- McReynolds L.
- Milisen R.
- Miller M. K.
- Milutinovic Z.
- Mueller P. B.
- Murry T.
- Murry T.
- National Center for Voice and Speech
- Newman K. B.
- Nilson H.
- Olswang L. B.
- Pahn J.
- Peacher G. M.
- Peacher G. M.
- Perkins W. H.
- Perkins W. H.
- Prater R. J.
- Ramig L.
- Ramig L.
- Ramig L.
- Ramig L.
- Ramig L.
- Ramig L.
- Ramig L.
- Ramig L. O.
- Ramig L. O.
- Robertson S.
- Roy N.
- Roy N.
- Roy N.
- Rubin J.
- Ruscello D.
- Sanders E. K.
- Sapir S.
- Sapir S.
- Sapir S.
- Sataloff R. T.
- Schearer W.
- Schiavetti N.
- Scott S.
- Senturia B. H.
- Shindo M. L.
- Smith E.
- Smith M.
- Smith M.
- Smith S.
- Stemple G. J.
- Stemple J.
- Stemple J.
- Stemple J. C.
- Titze I.
- Toohil R. J.
- Verdolini K.
- Ward P.
- Watterson T.
- White F.
- Wilson D.
- Wilson F.
- Winer B.
- World Health Organization
- Yairi E.
- Yamaguchi H.
- Yamaguchi H.
- Yorkston K.
- Publication venue
- 'American Speech Language Hearing Association'
- Publication date
- Field of study
Arkansas
- Author
- Bailey Anne J.
- Bailey Anne J.
- Bailey Anne J.
- Bailey Anne J.
- Bailey Anne J.
- Banasik Michael
- Barnes Kenneth C.
- Barnhill Floyd R.
- Baxter William
- Bergeron Arthur W.
- Bosse David
- Brown D. Alexander
- Brown Walter Lee
- Bunch Clea Lutz
- Burrow Roy D.
- Castel Albert
- Castel Albert G.
- Castel Albert G.
- Catalfano‐Serio Christina
- Christ Mark K.
- Christ Mark K.
- Christ Mark K.
- Christ Mark K.
- Christ Mark K.
- Christ Mark K.
- Christ Mark K.
- Clifford Roy A.
- Collier Calvin A.
- Collier Calvin A.
- Collier Calvin A.
- Connor Sam
- Cozzens Peter
- Cunningham Frank
- Cutrer Thomas W.
- Davis William C.
- DeBlack Thomas
- Dougan Michael B.
- Edwards Dale
- Elder Donald C.
- Fischer LeRoy H.
- Fisher Mike
- Forsyth Michael J.
- Franks Kenny A.
- Franzmann Tom
- Gaines W. Craig
- Gill Samuel T.
- Gregory Ival L.
- Hanson Maynard J.
- Harrell John M.
- Hartje Robert H.
- Hartsell Henry F.
- Hughes Michael A.
- Johansson M. Jane
- Johnson Boyd W.
- Joslyn Mauriel Phillips
- Kaufman A.F.
- Kerby Robert L.
- Kohl Rhonda M.
- Leeper Wesley T.
- Lovett Bobby L.
- Lowe Richard
- Mackey Robert
- Moneyhon Carl H.
- Moneyhon Carl H.
- Moneyhon Carl H.
- Moneyhon Carl H.
- Moulton Gary E.
- Neal Diane
- Neal Diane
- Neal Diane
- Neal Diane
- O'Flaherty Daniel
- Parks Joseph H.
- Pitcock Cynthia DeHaven
- Pollan Carolyn
- Purdue Howell
- Rea Ralph R.
- Reynolds Thomas C.
- Robertson Brian K.
- Robertson Brian K.
- Rushing Anthony C.
- Rushing Anthony C.
- Scherneckau August
- Scott Kim Allen
- Scott Kim Allen.
- Shalhope Robert E.
- Sharp Arthur G.
- Shea William L.
- Springer Francis
- Stafford L. Scott
- Stafford L. Scott
- Staples Thomas S.
- Stone Jayme Lynne
- Strong Henry A.
- Sutherland Daniel E.
- Sutherland Daniel E.
- Sword Wiley
- Symonds Craig L.
- Thomas David Y.
- Thomas David Y.
- Walter John F.
- Warren Luther E.
- Watson Lady Elizabeth
- Willis James
- Woods James M.
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Determinants of Disuse-Induced Skeletal Muscle Atrophy: Exercise and Nutrition Countermeasures to Prevent Protein Loss
- Author
- Adams GR Caiozzo VJ, Baldwin KM
- Adams GR McCue SA, Bodell PW, Zeng
- Alkner BA Berg HE, Kozlovskaya I,
- Alkner BA Tesch PA
- Alkner BA Tesch PA
- Allen DL Linderman JK, Roy RR, Big
- Allen DL Yasui W, Tanaka T, Ohira
- Anthony JC Lang CH, Crozier SJ, An
- Baar K Esser K
- Babij P Booth FW
- Baker JH Margolis RN
- Baldwin KM Haddad F
- Baldwin KM Herrick RE, McCue SA
- Berg HE Tesch PA
- Bey L Akunuri N, Zhao P, Hoffman E
- Bey L Hamilton MT
- Bianchi G Marzocchi R, Agostini F,
- Blomstrand E Eliasson J, Karlsson
- Booth FW
- Booth FW Criswell DS
- Caiozzo VJ Baker MJ, McCue SA, Bal
- Caiozzo VJ Haddad F, Baker MJ, Her
- Carroll CC Fluckey JD, Williams RH
- Chen YW Nader GA, Baar KR, Fedele
- Childs TE Spangenburg EE, Vyas DR,
- Criswell DS Booth FW, DeMayo F, Sc
- D'Aunno DS Robinson RR, Smith
- Dodd SL Koesterer TJ
- Dupont-Versteegden EE Houle JD, Gu
- Durham WJ Li YP, Gerken E, Farid M
- Edgerton VR Roy RR, Allen DL, Mont
- Ferrando AA Lane HW, Stuart CA, Da
- Ferrando AA Tipton KD, Bamman MM,
- Fitts RH Riley DR, Widrick JJ
- Fitts RH Riley DR, Widrick JJ
- Flü
- Fluckey JD Dupont-Versteegden EE,
- Fluckey JD Dupont-Versteegden EE,
- Fluckey JD Knox M, Smith LM, Dupon
- Gamrin L Berg HE, Essen P, Tesch P
- Glass DJ
- Glickman MH Ciechanover A
- Goldspink DF Garlick PJ, McNurlan
- Graham SC Roy RR, Hauschka EO, Edg
- Grichko VP Heywood-Cooksey A, Kidd
- Grigor'ev AI Shenkman BS, Bel
- Grindeland RE Roy RR, Edgerton VR,
- Haddad F Baldwin KM, Tesch PA
- Haddad F Roy RR, Zhong H, Edgerton
- Haddad F Roy RR, Zhong H, Edgerton
- Hauschka EO Roy RR, Edgerton VR
- Henriksen EJ Rodnick KJ, Mondon CE
- Herbison GJ Jaweed MM, Ditunno JF
- Hicke L Dunn R
- Hirose M Kaneki M, Sugita H, Yasuh
- Hornberger TA Hunter RB, Kandarian
- Howard G Steffen JM, Geoghegan TE
- Hunter RB Mitchell-Felton H, Essig
- Hunter RB Stevenson E, Koncarevic
- Ikemoto M Nikawa T, Takeda S, Wata
- Jaspers SR Fagan JM, Satarug S, Co
- Jaspers SR Fagan JM, Tischler ME
- Jaspers SR Tischler ME
- Kandarian SC Jackman RW
- Karlsson HK Nilsson PA, Nilsson J,
- Kasper CE White TP, Maxwell LC
- Kimball SR Farrell PA, Jefferson L
- Kimball SR Jefferson LS
- Kimball SR Jefferson LS
- Kimball SR Jefferson LS
- Kobayashi H Kato H, Hirabayashi Y,
- Koesterer TJ Dodd SL, Powers S
- Krawiec BJ Frost RA, Vary TC, Jeff
- Laviano A Muscaritoli M, Cascino A
- Lee SW Dai G, Hu Z, Wang X, Du J,
- Leeuwenburgh C Gurley CM, Strotman
- Leonard JI Leach CS, Rambaut PC
- Linderman JK Gosselink KL, Booth F
- Litvinova KS Kozlovskaia IB, Nemir
- Loughna P Goldspink G, Goldspink D
- Loughna PT Goldspink DF, Goldspink
- Matuszczak Y Arbogast S, Reid MB
- Mondon CE Rodnick KJ, Dolkas CB, A
- Morris CA Morris LD, Kennedy AR, S
- Munoz KA Satarug S, Tischler ME
- Musacchia XJ Steffen JM, Fell RD
- Naito H Powers SK, Demirel HA, Sug
- Nguyen HX Tidball JG
- Nikawa T Ishidoh K, Hirasaka K, Is
- Ohira Y Yoshinaga T, Nomura T, Kaw
- Ohira Y Yoshinaga T, Ohara M, Nona
- Ohnishi T Takahashi A, Wang X, Ohn
- Ohnishi T Wang X, Fukuda S, Takaha
- Paddon-Jones D Sheffield-Moore M,
- Paddon-Jones D Sheffield-Moore M,
- Parkington JD LeBrasseur NK, Siebe
- Patterson GT Dettbarn WD
- Reznick AZ Menashe O, Bar-Shai M,
- Riley DA Bain JL, Romatowski JG, F
- Riley DA Bain JL, Thompson JL, Fit
- Riley DA Bain JL, Thompson JL, Fit
- Riley DA Slocum GR, Bain JL, Sedla
- Roy RR Baldwin KM, Edgerton VR
- Sartorelli V Fulco M
- Schulte LM Navarro J, Kandarian SC
- Selsby JT Dodd SL
- Shah OJ Anthony JC, Kimball SR, Je
- Shangraw RE Stuart CA, Prince MJ,
- Shimomura Y Honda T, Shiraki M, Mu
- Shimomura Y Yamamoto Y, Bajotto G,
- Siu PM Alway SE
- St Pierre BA Tidball JG
- St-Amand J Okamura K, Matsumoto K,
- Steffen JM Fell RD, Geoghegan TE,
- Steffen JM Musacchia XJ
- Stein TP
- Stein TP Donaldson MR, Leskiw MJ,
- Stein TP Leskiw MJ, Schluter MD
- Stein TP Schluter MD
- Stein TP Schluter MD
- Stevenson EJ Giresi PG, Koncarevic
- Stuart CA Shangraw RE, Peters EJ,
- Stuart CA Shangraw RE, Prince MJ,
- Sugiura T Abe N, Nagano M, Goto K,
- TADA O
- Taillandier D Bigard X, Desplanche
- Tesch PA Ekberg A, Lindquist DM, T
- Thomason DB Biggs RB, Booth FW
- Thomason DB Herrick RE, Surdyka D,
- Tischler ME
- Tischler ME Satarug S, Eisenfeld S
- Tobin BW Uchakin PN, Leeper-Woodfo
- Vermaelen M Marini JF, Chopard A,
- Vijayan K Thompson JL, Norenberg K
- Whedon GD Lutwak L, Rambaut PC, Wh
- Widrick JJ Knuth ST, Norenberg KM,
- Witzmann FA Kim DH, Fitts RH
- Yimlamai T Dodd SL, Borst SE, Park
- YOKOGOSHI H
- Yokota H Sun HB, Malacinski GM
- YOSHIZAWA F
- Zdanowicz MM Teichberg S
- Zhang LF Sun B, Cao XS, Liu C, Yu
- Zhou MY Klitgaard H, Saltin B, Roy
- Publication venue
- 'Center for Academic Publications Japan'
- Publication date
- 01/01/2006
- Field of study