Correlation of fluorescence and photocatalytic activity of co-doped Tio2

Co-doped TiO2 (0.5-4 mol%) photocatalysts were synthesized via sol-gel method and their physical and chemical properties were investigated. Addition of Co oxides dopants induced anatase to rutile phase transition and reduced the band gap energy of TiO2. The fluorescence result indicated that the electron-hole recombination rate was reduced with the presence of Co oxides dopant. The best photocatalyst obtained was 3Co-TiO2 which enhanced the photocatalytic activity of TiO2 by 10 folds to 26.6%. The importance of fluorescence properties of Co-doped TiO2 towards its photodegradation of Congo Red was presented

Photodegradation of Malachite Green by Immobilization of Titanium Dioxide on Glass Plates

The effects of pH, contact time, initial dye concentration, numbers of dip coating, light sources and repetitive usage of dip-coated TiO2 were studied in batch experiments in order to investigate the photodegradation efficiency of malachite green in aqueous solution by using titanium dioxide, TiO2 immobilized on glass plates. The photodegradation of malachite green was found to be more effective at lower initial dye concentration. Kinetic studies showed good correlation coefficient for a pseudo-first order kinetic model. The removal of malachite green was dependent on the TiO2 loading where the percentage removal of malachite green was 92.15, 94.28 and 98.43 % for 5, 10 and 15 number of TiO2 dip-coating, respectively. Among the three light sources used, sunlight possessed the highest removal efficiency with 100 % of removal of dye in 6 h of irradiation. The degradation of malachite green was enhanced in basic solution compared with acidic solution due to the amphoteric property of TiO2. The decolourization efficiency was found to be decreased after each repetitive usage of dip-coated TiO2 glass plates. However, the immobilized TiO2 still displayed a good performance in the removal of malachite green.

XRCC1, but not APE1 and hOGG1 gene polymorphisms is a risk factor for pterygium.

PurposeEpidemiological evidence suggests that UV irradiation plays an important role in pterygium pathogenesis. UV irradiation can produce a wide range of DNA damage. The base excision repair (BER) pathway is considered the most important pathway involved in the repair of radiation-induced DNA damage. Based on previous studies, single-nucleotide polymorphisms (SNPs) in 8-oxoguanine glycosylase-1 (OGG1), X-ray repair cross-complementing-1 (XRCC1), and AP-endonuclease-1 (APE1) genes in the BER pathway have been found to affect the individual sensitivity to radiation exposure and induction of DNA damage. Therefore, we hypothesize that the genetic polymorphisms of these repair genes increase the risk of pterygium.MethodsXRCC1, APE1, and hOGG1 polymorphisms were studied using fluorescence-labeled Taq Man probes on 83 pterygial specimens and 206 normal controls.ResultsThere was a significant difference between the case and control groups in the XRCC1 genotype (p=0.038) but not in hOGG1 (p=0.383) and APE1 (p=0.898). The odds ratio of the XRCC1 A/G polymorphism was 2.592 (95% CI=1.225-5.484, p=0.013) and the G/G polymorphism was 1.212 (95% CI=0.914-1.607), compared to the A/A wild-type genotype. Moreover, individuals who carried at least one C-allele (A/G and G/G) had a 1.710 fold increased risk of developing pterygium compared to those who carried the A/A wild type genotype (OR=1.710; 95% CI: 1.015-2.882, p=0.044). The hOGG1 and APE1 polymorphisms did not have an increased odds ratio compared with the wild type.ConclusionsXRCC1 (Arg399 Glu) is correlated with pterygium and might become a potential marker for the prediction of pterygium susceptibility

Epidermal growth factor receptor regulates β-catenin location, stability, and transcriptional activity in oral cancer

<p>Abstract</p> <p>Background</p> <p>Many cancerous cells accumulate β-catenin in the nucleus. We examined the role of epidermal growth factor receptor (EGFR) signaling in the accumulation of β-catenin in the nuclei of oral cancer cells.</p> <p>Results</p> <p>We used two strains of cultured oral cancer cells, one with reduced EGFR expression (OECM1 cells) and one with elevated EGFR expression (SAS cells), and measured downstream effects, such as phosphorylation of β-catenin and GSK-3β, association of β-catenin with E-cadherin, and target gene regulation. We also studied the expression of EGFR, β-catenin, and cyclin D1 in 112 samples of oral cancer by immunostaining. Activation of EGFR signaling increased the amount of β-catenin in the nucleus and decreased the amount in the membranes. EGF treatment increased phosphorylation of β-catenin (tyrosine) and GSK-3β(Ser-(9), resulting in a loss of β-catenin association with E-cadherin. TOP-FLASH and FOP-FLASH reporter assays demonstrated that the EGFR signal regulates β-catenin transcriptional activity and mediates cyclin D1 expression. Chromatin immunoprecipitation experiments indicated that the EGFR signal affects chromatin architecture at the regulatory element of cyclin D1, and that the CBP, HDAC1, and Suv39h1 histone/chromatin remodeling complex is involved in this process. Immunostaining showed a significant association between EGFR expression and aberrant accumulation of β-catenin in oral cancer.</p> <p>Conclusions</p> <p>EGFR signaling regulates β-catenin localization and stability, target gene expression, and tumor progression in oral cancer. Moreover, our data suggest that aberrant accumulation of β-catenin under EGFR activation is a malignancy marker of oral cancer.</p

Learning Styles of Undergraduate and Graduate Physical Therapy Students in Taiwan

AbstractThe research was conducted to identify the learning styles of undergraduate and graduate physical therapy students in Taiwan and to examine the associations between learning style and academic performance. Basic data and Kolb's Learning Style Inventory were obtained from 52 participants from one university. The most commonly occurring style of learner was assimilator (44%), followed by diverger (23%), accommodator (15%), and converger (17%). There was no significant difference in academic performance among the four different styles of learners. Qualitative analyses provided further understanding of the preferred learning and teaching strategies. The different strategies are recommended to meet students’ learning preferences

Differential evolutionary conservation of motif modes in the yeast protein interaction network

BACKGROUND: The importance of a network motif (a recurring interconnected pattern of special topology which is over-represented in a biological network) lies in its position in the hierarchy between the protein molecule and the module in a protein-protein interaction network. Until now, however, the methods available have greatly restricted the scope of research. While they have focused on the analysis in the resolution of a motif topology, they have not been able to distinguish particular motifs of the same topology in a protein-protein interaction network. RESULTS: We have been able to assign the molecular function annotations of Gene Ontology to each protein in the protein-protein interactions of Saccharomyces cerevisiae. For various motif topologies, we have developed an algorithm, enabling us to unveil one million "motif modes", each of which features a unique topological combination of molecular functions. To our surprise, the conservation ratio, i.e., the extent of the evolutionary constraints upon the motif modes of the same motif topology, varies significantly, clearly indicative of distinct differences in the evolutionary constraints upon motifs of the same motif topology. Equally important, for all motif modes, we have found a power-law distribution of the motif counts on each motif mode. We postulate that motif modes may very well represent the evolutionary-conserved topological units of a protein interaction network. CONCLUSION: For the first time, the motifs of a protein interaction network have been investigated beyond the scope of motif topology. The motif modes determined in this study have not only enabled us to differentiate among different evolutionary constraints on motifs of the same topology but have also opened up new avenues through which protein interaction networks can be analyzed

Emphysematous Prostatitis Caused by Klebsiella pneumoniae

Emphysematous prostatitis is a rare condition that is characterized by gas and abscess accumulation in the prostate. We report a 60-year-old man with emphysematous prostatitis caused by Klebsiella pneumoniae. He had a history of recently diagnosed diabetes mellitus and a 16-year history of alcoholic liver cirrhosis. He was admitted due to fever, dysuria and difficult urination. Physical examination revealed lower abdominal tenderness and prostatic fluctuance on digital examination. Leukocytosis, pyuria and elevated C-reactive protein were found. Abdominal radiography disclosed a collection of abnormal air pockets in the lower pelvic cavity and computed tomography scans corroborated the existence of extensive air collection in the prostate. Under the impression of emphysematous prostatitis, the patient was successfully treated with transurethral incision of the prostate and antibiotics for 6 weeks; there were no urinary sequelae during 6 months of follow-up. [J Formos Med Assoc 2007;106(1):74-77

Tartaric Acid Modified Rice Hull as a Sorbent for Methylene Blue Removal

Problem statement: Improper dye discharge from various industries such as textile, paper, cosmetic and plastics into receiving streams can be one of the sources towards water pollution. The release of these effluents not only causes various disruptions in the ecosystems, but also poses hazard effect as most of the dyes are highly toxic, mutagenic and carcinogenic in nature. Approach: To prepare an inexpensive and efficient sorbent by chemically modifying rice hull for the removal of Methylene Blue (MB) which is predominantly used in coloring acrylic fiber. Batch experiments were carried out for the removal of MB from aqueous solution by using Tartaric Acid Modified Rice Hull (TARH). Parameters studied include effect of pH, contact time, initial dye concentration and agitation rate and sorption isotherm. Results: From the results, the percentage uptake of MB increased with increasing contact time and agitation rate. Based on the linear regression correlation coefficient, R2, the system under study is more appropriately described by the pseudo-second order model. Maximum sorption capacity calculated from the Langmuir model is 25.0 mg g-1 for MB. Conclusion: The study has shown the effectiveness of TARH in the removal of MB, a basic dye from synthetic solutions. © 2010 Science Publications

Viewing versus Experiencing in Adopting Somatosensory Technology for Smart Applications

Emerging somatosensory technology offers unprecedented opportunities for researchers and industrial practitioners to design a touchless smart home system. However, existing touchless smart home systems often fail to attract a satisfying level of acceptance among home owners. The experience users have with the touchless system is key to making somatosensory technology a pervasive computing home application, yet little research has been conducted to assess the influence of direct and indirect experience on user’s behavioral intention to use somatosensory technology. To address this research gap, this paper set up an experimental design to investigate the influence of direct and indirect experience in user technology acceptance. Using an in-house developed touchless system, two experimental studies (i.e., video observation versus product trial) were conducted with sixty-two participants to investigate whether the user experience has an impact on the adoption decision. Our findings indicate that direct experience has an impact on a user’s acceptance of somatosensory technology. We found a significant difference in the relationships between perceived complexity and usage intentions. Perceived complexity was a significant predictor of an individual’s behavioral intention to use the touchless system after video observation, while its relationship to usage intention was insignificant after the user had direct experience with touchless system. Our study reveals an important implication for somatosensory technology marketers, in which product trial (direct experience) engenders more reliable inferences than does exposure to video demonstration (indirect experience). Based on this, companies should devise marketing programme involving direct experience (e.g., product trial and showroom visit) to promote new somatosensory-enabled smart home systems. The results of the study also demonstrate that user experience in research design may influence the results of the Technology Acceptance Model (TAM) studies. Available at: https://aisel.aisnet.org/pajais/vol6/iss3/2