2,503 research outputs found
Highly Variable Genomic Landscape of Endogenous Retroviruses in the C57BL/6J Inbred Strain, Depending on Individual Mouse, Gender, Organ Type, and Organ Location.
Transposable repetitive elements, named the "TREome," represent ~40% of the mouse genome. We postulate that the germ line genome undergoes temporal and spatial diversification into somatic genomes in conjunction with the TREome activity. C57BL/6J inbred mice were subjected to genomic landscape analyses using a TREome probe from murine leukemia virus-type endogenous retroviruses (MLV-ERVs). None shared the same MLV-ERV landscape within each comparison group: (1) sperm and 18 tissues from one mouse, (2) six brain compartments from two females, (3) spleen and thymus samples from four age groups, (4) three spatial tissue sets from two females, and (5) kidney and liver samples from three females and three males. Interestingly, males had more genomic MLV-ERV copies than females; moreover, only in the males, the kidneys had higher MLV-ERV copies than the livers. Perhaps, the mouse-, gender-, and tissue/cell-dependent MLV-ERV landscapes are linked to the individual-specific and dynamic phenotypes of the C57BL/6J inbred population
Progressive Processing of Continuous Range Queries in Hierarchical Wireless Sensor Networks
In this paper, we study the problem of processing continuous range queries in
a hierarchical wireless sensor network. Contrasted with the traditional
approach of building networks in a "flat" structure using sensor devices of the
same capability, the hierarchical approach deploys devices of higher capability
in a higher tier, i.e., a tier closer to the server. While query processing in
flat sensor networks has been widely studied, the study on query processing in
hierarchical sensor networks has been inadequate. In wireless sensor networks,
the main costs that should be considered are the energy for sending data and
the storage for storing queries. There is a trade-off between these two costs.
Based on this, we first propose a progressive processing method that
effectively processes a large number of continuous range queries in
hierarchical sensor networks. The proposed method uses the query merging
technique proposed by Xiang et al. as the basis and additionally considers the
trade-off between the two costs. More specifically, it works toward reducing
the storage cost at lower-tier nodes by merging more queries, and toward
reducing the energy cost at higher-tier nodes by merging fewer queries (thereby
reducing "false alarms"). We then present how to build a hierarchical sensor
network that is optimal with respect to the weighted sum of the two costs. It
allows for a cost-based systematic control of the trade-off based on the
relative importance between the storage and energy in a given network
environment and application. Experimental results show that the proposed method
achieves a near-optimal control between the storage and energy and reduces the
cost by 0.989~84.995 times compared with the cost achieved using the flat
(i.e., non-hierarchical) setup as in the work by Xiang et al.Comment: 41 pages, 20 figure
Intraosseous Hemangioma of the Middle Turbinate Misdiagnosed As a Nasal Polyp
Intraosseous hemangiomas account for 1% of all bone tumors and primarily originate from the vertebral column and skull bones. However, intraosseous hemangiomas of the nasal cavity are extremely rare. Here, we report a case of intraosseous hemangioma with a cavernous pattern arising from the middle turbinate that was preoperatively misdiagnosed as chronic rhinosinusitis with polyps. Except for nasal obstruction, there were no specific rhinologic symptoms. The tumor was excised en bloc by the endoscopic endonasal approach without preoperative embolization
A Korean multi-center, real-world, retrospective study of first-line pazopanib in unselected patients with metastatic renal clear-cell carcinoma
Focal Eosinophilic Necrosis of the Liver in Patients with Underlying Gastric or Colorectal Cancer: CT Differentiation from Metastasis
High-resolution analysis of condition-specific regulatory modules in Saccharomyces cerevisiae
A novel approach for identifying condition-specific regulatory modules in yeast reveals functionally distinct coregulated submodules
An Examination of Contextual and Organizational Factors Influencing Police Use of Force: A Multilevel Model
The current study attempts to bridge this gap in research between contextual factors and police use of force. It also deepens our understandings of the association between organizational factors and use of force by incorporating police training into the analytical model. Finally, this study expands prior research by including multiple police agencies in the sample, thus producing research findings that can be more easily generalized
PLANTAR PRESSURE DISTRIBUTION ANALYSIS OF ALPINE AND BOARDERCROSS SNOWBOARDERS’ CARVING TURNS
Plantar pressure distribution analysis of alpine and boarder-cross snowboarders’ carving turn was performed to provide instructors and snowboarders with scientific and quantitative data for evaluation of the turn. Snowboarders from Korean National Team for 2018 Pyeongchang Winter Olympics were chosen as subjects. To allow on-snow measurements of plantar pressure distribution, the boots were outfitted with pressure sensitive insoles. The carving turn section was divided into 5 events and 4 phases of which force, maximum pressure, and plantar contact area were analyzed. Comprehensive kinematical analysis was conducted which indicated the major features of pressure distribution in two different sporting events. The proposed results can be used as a reference for improvement of the training method in snowboarding
Retina-Inspired Carbon Nitride-Based Photonic Synapses for Selective Detection of UV Light
Photonic synapses combine sensing and processing in a single device, so they are promising candidates to emulate visual perception of a biological retina. However, photonic synapses with wavelength selectivity, which is a key property for visual perception, have not been developed so far. Herein, organic photonic synapses that selectively detect UV rays and process various optical stimuli are presented. The photonic synapses use carbon nitride (C3N4) as an UV-responsive floating-gate layer in transistor geometry. C3N4 nanodots dominantly absorb UV light; this trait is the basis of UV selectivity in these photonic synapses. The presented devices consume only 18.06 fJ per synaptic event, which is comparable to the energy consumption of biological synapses. Furthermore, in situ modulation of exposure to UV light is demonstrated by integrating the devices with UV transmittance modulators. These smart systems can be further developed to combine detection and dose-calculation to determine how and when to decrease UV transmittance for preventive health care.
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