3,929 research outputs found
An Analysis of Consuming Behavior Model for Adopting Knowledge Intensive Technological Product: The Case of MDA
The objective of this research is to analyze the correlation between consumers’ adoption of MDA and some of its influential variables, namely innovativeness, procurement types, involvement, the degree of Internet used and the basic characteristics of consumers. This paper provides a new model to explain the influent effects between consumers’ adoption of MDA and its influential factors mentioned above. The conclusions of this study are: (1) the curves of consumers’ basic characteristics versus adoption of MDA are convex-type. (2) The consumers’ age, name-list size, innovation adoption, goal-oriented and Internet usage frequency attributes have direct and positive effects on PDA adoption. (3) The innovativeness of consumers may be used to explain the reason of Consumers’ procurement style. (4) The innovativeness of consumers may be used to exploit and design the product differentiation strategy. (5) The basic characteristics of consumers may be used to exploit and design the promotion and market segmentation strategies
BIOMECHANICAL ANALYSIS OF THE GRAB AND TRACK SWIMMING STARTS
The aim of this study was to compare the grab and track competitive swimming starts. Twelve male college competitive swimmers (six used the grab start and six the track start) participated in this study. Data were collected from two video cameras (60Hz) above water. The video data were digitized and analysis was performed with the Kwon3D Motion Analysis system. No significant differences existed between the two groups for flight time and distance, time to 12m, takeoff velocity and angle, entry velocity and angle and the center of mass at highest position above water. The track start had the centre of mass on the block more towards the rear and a shorter block time (
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A Hybrid Meta-heuristic for the Container Loading Problem
It is very common in an enterprise daily operation to solve Container Loading Problem (CLP). Especially, it is an important issue in the logistic management. The problem aims to determine the arrangement of objects with the best utilization ratio in a container. It belongs to the combinatorial optimization problem. In this paper, a two-phased method focusing on the improvement of the efficiency and on the reducing of the problem size is proposed. In the first phase, a constructive method incorporated with a decision rule borrowing from ant colony optimization is used to construct tower set. The pheromone updating mechanism is useful in choosing proper object while constructing tower using decision rule. In the second phase, an improvement method based on genetic algorithm is used. First, the method sorts the towers by the utilization ratio and then assigns a number to each tower accordingly. The chromosome is a sequence of tower numbers which represents the arrangement of towers in the container’s bottom plane. The fitness function is defined as the utilization ratio. A new structure to store the pheromone is proposed which can help the ant in choosing the appropriate object while constructing tower. In this way, the efficiency of the method and the utilization of the container are improved
EFFECTS OF WHOLE BODY VIBRATION TRAINING ON KNEE EXTENSOR MUSCLE STRENGTH AND RATE OF FORCE DEVELOPMENT
This study compared the effects of 8-week whole-body vibration (WBV) training programs on knee extensor muscle strength and rate of force development. Twenty physically active male subjects were randomly assigned to a whole-body vibration training group (WBV; n =10) or a sham training group (SHAM; n = 10). Maximal voluntary isometric joint moment, rate of force development (RFD) and contractile impulse of the knee extensors were assessed before and after the training period. There were significant differences between WBV and sham groups on improvement percentage of maximum joint moment, RFD and
contractile impulse in knee extensor. We concluded that not only knee extensor muscle strength could be enhanced but also muscle contractile abilty could be faster after a 8-week WBV training program
Pseudozyma spp. and Barnettozyma spp. effectively kill cancer cells in vitro
AbstractCancer is the overall leading cause of death in developed countries and also worldwide, and being able to exploit an effective anticancer drug is the aim of all cancer scientists. However, many of the synthetic drugs produced so far usually cause serious side effects, which reduces their therapeutic efficacy. Discovering new drugs or auxiliary therapies derived from natural products might thus provide a novel opportunity for cancer therapy. A recent study reported that some lethal toxins can maintain their activity after being injected into mice. We therefore used two Pseudozyma spp. and three Barnettozyma spp. to examine whether these killer yeasts can preserve their lethal effect on cancer cells under the physical environment (optimum pH, temperature and osmolality, supporting a living cell accomplishes to proliferate, metabolize, differentiate and survive). Our preliminary results showed that both Barnettozyma spp. and Pseudozyma spp. have stronger cytotoxicity against HepG2 than Chang’s liver cells. According to the results of two-dimensional difference gel electrophoresis (2D-DIGE), a total of 115 and 27 proteins differentially expressed by 1.5-fold or more were observed for HepG2 and Chang’s liver cells, respectively. Furthermore, we explored the mechanism involved in the effect of the lethal yeast filtrates on liver cancer cells using 2D-DIGE and mass spectrometry
Graptopetalum paraguayense
Role of inflammation-induced oxidative stress in the pathogenesis and progression of chronic inflammatory airways diseases has received increasing attention in recent years. Nuclear factor erythroid 2-related factor 2 is the primary transcription factor that regulates the expression of antioxidant and detoxifying enzymes. Graptopetalum paraguayense E. Walther, a vegetable consumed in Taiwan, has been used in folk medicine for protection against liver injury through elevating antioxidation. Recently, we found that gallic acid is an active compound of Graptopetalum paraguayense E. Walther, which has been reported to inhibit T-helper 2 cytokines. Currently, we assumed that Graptopetalum paraguayense E. Walther may potentially protect against ovalbumin-induced allergy and airway inflammation. Results demonstrated that Graptopetalum paraguayense E. Walther ethanolic extracts (GPE) clearly inhibited airway inflammation, mucus cell hyperplasia, and eosinophilia in OVA-challenged mice. Additionally, GPE also prevented T-cell infiltration and Th2 cytokines, including interleukin- (IL-)4, IL-5, and IL-13 generations in bronchial alveolar lavage fluid. The adhesion molecules ICAM-1 and VCAM-1 were substantially reduced by GPE treatment mediated by Nrf2 activation. Moreover, GPE attenuated GATA3 expression and inhibited Th2 signals of the T cells. These findings suggested that GPE ameliorated the development of airway inflammation through immune regulation
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