LANDSAT derived snowcover as an input variable for snowmelt runoff forecasting in south central Colorado

There are no author-identified significant results in this report

Conducting Polyelectrolyte Complexes: Assembly, Structure, and Transport

Decades of progress have yielded a tremendous variety of organic electronics, with great strides in the development of photovoltaics, thermoelectrics and other flexible devices. Ubiquitous in these research areas are films of poly(3,4-ethylenedioxythiophene): poly(styrenesulfonic acid) (PEDOT: PSS), a complex of oppositely-charged polyelectrolytes initially suspended in water before film formation. This material has high electronic conductivity and good water processability. Pristine film conductivity is somewhat low, but is dramatically enhanced through simple treatments like ionic liquid addition or shear. Can this enhancement be understood so that further optimization might render PEDOT: PSS commercially viable? PEDOT: PSS is a complicated material, with electrostatic complexation between PEDOT and oppositely-charged PSS, dissociated counterions and an inherent insolubility of PEDOT in water. These characteristics among others muddle the already challenging task of understanding the film formation process. In this doctoral thesis work, the goal is to build on our fundamental understanding of PEDOT: PSS and conducting polyelectrolyte complexes in general. The structural aspects of PEDOT: PSS dispersions are studied upon the addition of four conductivity enhancers: EMIM BF4, NaCl, DMSO and EG. PEDOT: PSS collects into many-chain charged micro-gels that are hundreds of nanometers in scale. An observed sensitivity to ionic strength underscores the dominance of electrostatic forces in PEDOT: PSS solutions. Micro-gels can macroscopically percolate or phase segregate, much like associating polymers. PEDOT: PSS conduction predominatly occurs electronically in films and ionically in solutions. When the four enhancers are introduced, no correlation is found between changes to film conductivity and changes to solution phenomenology. This apparent lack of correlation strengthens the widely-held belief that conductivity enhancement is closely linked to PEDOT ordering. Langevin dynamics simulations show that PEDOT clusters into stacked domains at high polymer concentration and ionic strength, and this clustering can be explained as an interplay between hydrophobic and electrostatic drivers. A new theory of polyelectrolyte complex phase separation is proposed, and it relies on induced dipoles formed from the association of oppositely-charged backbones. It predicts the phase behavior for model systems, but does not apply directly to PEDOT: PSS. Nevertheless, it gives insight into the role of dipoles for complex coacervation

Applications systems verification and transfer project. Volume 4: Operational applications of satellite snow cover observations. Colorado Field Test Center

The study was conducted on six watersheds ranging in size from 277 km to 3460 km in the Rio Grande and Arkansas River basins of southwestern Colorado. Six years of satellite data in the period 1973-78 were analyzed and snowcover maps prepared for all available image dates. Seven snowmapping techniques were explored; the photointerpretative method was selected as the most accurate. Three schemes to forecast snowmelt runoff employing satellite snowcover observations were investigated. They included a conceptual hydrologic model, a statistical model, and a graphical method. A reduction of 10% in the current average forecast error is estimated when snowcover data in snowmelt runoff forecasting is shown to be extremely promising. Inability to obtain repetitive coverage due to the 18 day cycle of LANDSAT, the occurrence of cloud cover and slow image delivery are obstacles to the immediate implementation of satellite derived snowcover in operational streamflow forecasting programs

Schwinger, Pegg and Barnett and a relationship between angular and Cartesian quantum descriptions

From a development of an original idea due to Schwinger, it is shown that it is possible to recover, from the quantum description of a degree of freedom characterized by a finite number of states (\QTR{it}{i.e}., without classical counterpart) the usual canonical variables of position/momentum \QTR{it}{and} angle/angular momentum, relating, maybe surprisingly, the first as a limit of the later.Comment: 7 pages, revised version, to appear on J. Phys. A: Math and Ge

Orthogonal, solenoidal, three-dimensional vector fields for no-slip boundary conditions

Viscous fluid dynamical calculations require no-slip boundary conditions. Numerical calculations of turbulence, as well as theoretical turbulence closure techniques, often depend upon a spectral decomposition of the flow fields. However, such calculations have been limited to two-dimensional situations. Here we present a method that yields orthogonal decompositions of incompressible, three-dimensional flow fields and apply it to periodic cylindrical and spherical no-slip boundaries.Comment: 16 pages, 2 three-part figure

Group 3 late embryogenesis abundant proteins from embryos of Artemia franciscana : structural properties and protective abilities during desiccation.

Group 3 late embryogenesis abundant (LEA) proteins are highly hydrophilic, and their expression is associated with desiccation tolerance in both plants and animals. Here we show that two LEA proteins from embryos of Artemia franciscana, AfrLEA2 and AfrLEA3m, are intrinsically disordered in solution but upon desiccation gain secondary structure, as measured by circular dichroism. Trifluoroethanol and sodium dodecyl sulfate are both shown to induce a-helical structure in AfrLEA2 and AfrLEA3m. Bioinformatic predictions of secondary-structure content for both proteins correspond most closely to conformations measured in the dry state. Because some LEA proteins afford protection to desiccation-sensitive proteins during drying and subsequent rehydration, we tested for this capacity in AfrLEA2 and AfrLEA3m. The protective capacities vary, depending on the target enzyme. For the cytoplasmic enzyme lactate dehydrogenase, neither AfrLEA2 nor AfrLEA3m, with or without trehalose present, was able to afford protection better than that provided by bovine serum albumin (BSA) under the same conditions. However, for another cytoplasmic enzyme, phosphofructokinase, both AfrLEA2 and AfrLEA3m in the presence of trehalose were able to afford protection far greater than that provided by BSA with trehalose. Finally, for the mitochondrial enzyme citrate synthase, 400-mg/mL AfrLEA3m without trehalose provided significantly more protection than the same concentration of either AfrLEA2 or BSA

Enhancing Nanoparticle Accumulation and Retention in Desmoplastic Tumors via Vascular Disruption for Internal Radiation Therapy

Aggressive, desmoplastic tumors are notoriously difficult to treat because of their extensive stroma, high interstitial pressure, and resistant tumor microenvironment. We have developed a combination therapy that can significantly slow the growth of large, stroma-rich tumors by causing massive apoptosis in the tumor center while simultaneously increasing nanoparticle uptake through a treatment-induced increase in the accumulation and retention of nanoparticles in the tumor. The vascular disrupting agent Combretastatin A-4 Phosphate (CA4P) is able to increase the accumulation of radiation-containing nanoparticles for internal radiation therapy, and the retention of these delivered radioisotopes is maintained over several days. We use ultrasound to measure the effect of CA4P in live tumor-bearing mice, and we encapsulate the radio-theranostic isotope 177Lutetium as a therapeutic agent as well as a means to measure nanoparticle accumulation and retention in the tumor. This combination therapy induces prolonged apoptosis in the tumor, decreasing both the fibroblast and total cell density and allowing further tumor growth inhibition using a cisplatin-containing nanoparticle