1,222 research outputs found

    Diversity of Formyltetrahydrofolate Synthetases in the Guts of the Wood-Feeding Cockroach Cryptocercus punctulatus and the Omnivorous Cockroach Periplaneta americana

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    We examined the diversity of a marker gene for homoacetogens in two cockroach gut microbial communities. Formyltetrahydrofolate synthetase (FTHFS or fhs) libraries prepared from a wood-feeding cockroach, Cryptocercus punctulatus, were dominated by sequences that affiliated with termite gut treponemes. No spirochete-like sequences were recovered from the omnivorous roach Periplaneta americana, which was dominated by Firmicutes-like sequences

    Some space shuttle tile/strain-isolator-pad sinusoidal vibration tests

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    Vibration tests were performed on the tile/strain-isolator-pad system used as thermal protection for the space shuttle orbiter. Experimental data on normal and in-plane vibration response and damping properties are presented. Three test specimens exhibited shear type motion during failures that occurred in the tile near the tile/strain-isolator-pad bond-line. A dynamic instability is described which has large in-plane motion at a frequency one-half that of the nominal driving frequency. Analysis shows that this phenomenon is a parametric response

    Best Practice Description Document

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    This work received support and funding from • The BOHAB project (Biological Oceanography of Harmful Algal Blooms off the west coast of Ireland) through the National Development Plan 2000 – 2006 with the support of the Marine Institute and the Marine RTDI (Research, Technology, Development and Innovation) Measure, Productive Sector Operational Programme, Grant-aid Agreement No. ST/02/01. • the ASIMUTH project (Applied simulations and Integrated modelling for the understanding of toxic and harmful algal blooms) through the European Research Council under the European Union's Seventh Framework Programme (FP7/2007-2013) for Research and Technological Development - EC FP7 Programme, Space Theme, Grant Agreement No. 261860 • the MyOcean 2 project through the EC FP7 Programme, Space Theme, Grant Agreement No. 283367 • the AtlantOS project through the European Union's Horizon 2020 research and innovation programme, Grant Agreement No. 633211 • The PRIMROSE (Predicting the impact of regional scale events on the aquaculture sector) project, co-financed by the European Regional Development Fund through the Interreg Atlantic Area Programme, EAPA_182/2016 • The CoCliME (Co-development of climate services for adaptation to changing marine ecosystems) project is part of the European Research Area for Climate Services (ERA4CS), an ERA-NET initiated by JPI Climate, and funded by EPA (IE), ANR (FR), BMBF (DE), UEFISCDI (RO), RCN (NO) and FORMAS (SE), with co-funding by the European Union (Grant Agreement No. 690462).This document describes the procedural steps in creating an information product focused on toxic and harmful phytoplankton. The product is an online Harmful Algal Bloom (HAB) bulletin for aquaculturists, who can face serious operational challenges in the days after a HAB event. Data from satellite, numerical hydrodynamic models and In-situ ocean observations are organised and presented into visual information products. These products are enhanced through local expert evaluation and their interpretation is summarised in the bulletin. This document aims to provide both process overviews (the “what” of the Best Practice in producing the bulletins) and detail procedures (the “how” of the Best Practice”) so that the bulletins may be replicated in other geographic regions.European Commissio

    Theory of spike timing based neural classifiers

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    We study the computational capacity of a model neuron, the Tempotron, which classifies sequences of spikes by linear-threshold operations. We use statistical mechanics and extreme value theory to derive the capacity of the system in random classification tasks. In contrast to its static analog, the Perceptron, the Tempotron's solutions space consists of a large number of small clusters of weight vectors. The capacity of the system per synapse is finite in the large size limit and weakly diverges with the stimulus duration relative to the membrane and synaptic time constants.Comment: 4 page, 4 figures, Accepted to Physical Review Letters on 19th Oct. 201

    Vibration characteristics of 1/8-scale dynamic models of the space-shuttle solid-rocket boosters

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    Vibration tests and analyses of six 1/8 scale models of the space shuttle solid rocket boosters are reported. Natural vibration frequencies and mode shapes were obtained for these aluminum shell models having internal solid fuel configurations corresponding to launch, midburn (maximum dynamic pressure), and near endburn (burnout) flight conditions. Test results for longitudinal, torsional, bending, and shell vibration frequencies are compared with analytical predictions derived from thin shell theory and from finite element plate and beam theory. The lowest analytical longitudinal, torsional, bending, and shell vibration frequencies were within + or - 10 percent of experimental values. The effects of damping and asymmetric end skirts on natural vibration frequency were also considered. The analytical frequencies of an idealized full scale space shuttle solid rocket boosted structure are computed with and without internal pressure and are compared with the 1/8 scale model results

    Metagenomic and functional analysis of hindgut microbiota of a wood-feeding higher termite

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    From the standpoints of both basic research and biotechnology, there is considerable interest in reaching a clearer understanding of the diversity of biological mechanisms employed during lignocellulose degradation. Globally, termites are an extremely successful group of wood-degrading organisms and are therefore important both for their roles in carbon turnover in the environment and as potential sources of biochemical catalysts for efforts aimed at converting wood into biofuels. Only recently have data supported any direct role for the symbiotic bacteria in the gut of the termite in cellulose and xylan hydrolysis. Here we use a metagenomic analysis of the bacterial community resident in the hindgut paunch of a wood-feeding ‘higher’ Nasutitermes species (which do not contain cellulose-fermenting protozoa) to show the presence of a large, diverse set of bacterial genes for cellulose and xylan hydrolysis. Many of these genes were expressed in vivo or had cellulase activity in vitro, and further analyses implicate spirochete and fibrobacter species in gut lignocellulose degradation. New insights into other important symbiotic functions including H_2 metabolism, CO_2-reductive acetogenesis and N_2 fixation are also provided by this first system-wide gene analysis of a microbial community specialized towards plant lignocellulose degradation. Our results underscore how complex even a 1-μl environment can be

    Quality assurance of approved out of programme psychiatry training and research over the past 5 years

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    Aims and method This paper intends to analyse the number of applications, trainee demographic and approval rate of those applying for out of programme training (OOPT) or out of programme research (OOPR) between January 2008 and April 2013 using the committee’s anonymised database. We also describe the process of application and approval by the Quality Assurance Committee. Results There were 90 applications, including 10 resubmissions during the 64-month period. Most applicants (77%) were higher trainees; 53% of applicants were from the London deanery; 60% of applications were for research posts and higher degrees (OOPR). Overall, 64% were approved by the committee: 70% for OOPRs and 53% for OOPTs. Clinical implications This paper shows with transparency the breakdown of applications to the Quality Assurance Committee. Around two-thirds of applications to the committee are supported (64%). Relatively few psychiatry trainees (2.5%) have applied for an OOPT or an OOPR over the past 5 years
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