Well-Being Correlates of Perceived Positivity Resonance: Evidence from Trait and Episode-Level Assessments

Positivity resonance is a type of interpersonal connection characterized by shared positivity, mutual care and concern, and behavioral and biological synchrony. Perceived positivity resonance is hypothesized to be associated with well-being. In three studies (N = 175; N = 120; N = 173), perceived positivity resonance was assessed at the trait level (Study 1) or the episode level, using the Day Reconstruction Method (Studies 2 and 3). Primary analyses reveal that perceived positivity resonance is associated with flourishing mental health, depressive symptoms, loneliness, and illness symptoms. These associations largely remain statistically significant when controlling for daily pleasant emotions or social interaction more generally. Ancillary analyses in Studies 2 and 3 support the construct validity of the episode-level assessment of perceived positivity resonance. The overall pattern of results is consistent with Positivity Resonance Theory. Discussion centers on avenues for future research and the need for behavioral interventions

Defect-engineered metal-organic frameworks (MOF-808) towards the improved adsorptive removal of organic dyes and chromium (vi) species from water

In this work, two defective zirconium-based metal-organic frameworks (Zr-MOFs), MOF-808-OH and MOF-808-NH2, were synthesized by partially replacing the 1,3,5-benzenetricarboxylate building block with 5-hydroxyisophthalate and 5-aminoisophthalate, respectively. The structural features of the defective materials were analyzed by powder X-ray diffraction (PXRD), scanning electron microscopy (SEM), nitrogen physisorption at 77 K, and thermogravimetric analysis (TGA). Importantly, the number of defect sites determined via proton nuclear magnetic resonance (1H-NMR) analysis of the digested materials was approximately 7 mol% for MOF-808-OH and 3 mol% for MOF-808-NH2. The presence of the defect sites increased the number of acidic centers on Zr-clusters originating from missing-linker nodes which accounted for a remarkable adsorption capacity towards various anionic organic dyes and chromium (vi) species. Compared to standard MOF-808, the defect-engineered ones showed significant increments by 30-60% in trapping capacity for anionic contaminants including sunset yellow, quinoline yellow, methyl orange, and potassium dichromate, while they exhibited modest improvements by 5-15% in the removal of cationic dyes, namely malachite green and methylene blue

Controllable Group Choreography Using Contrastive Diffusion

Music-driven group choreography poses a considerable challenge but holds significant potential for a wide range of industrial applications. The ability to generate synchronized and visually appealing group dance motions that are aligned with music opens up opportunities in many fields such as entertainment, advertising, and virtual performances. However, most of the recent works are not able to generate high-fidelity long-term motions, or fail to enable controllable experience. In this work, we aim to address the demand for high-quality and customizable group dance generation by effectively governing the consistency and diversity of group choreographies. In particular, we utilize a diffusion-based generative approach to enable the synthesis of flexible number of dancers and long-term group dances, while ensuring coherence to the input music. Ultimately, we introduce a Group Contrastive Diffusion (GCD) strategy to enhance the connection between dancers and their group, presenting the ability to control the consistency or diversity level of the synthesized group animation via the classifier-guidance sampling technique. Through intensive experiments and evaluation, we demonstrate the effectiveness of our approach in producing visually captivating and consistent group dance motions. The experimental results show the capability of our method to achieve the desired levels of consistency and diversity, while maintaining the overall quality of the generated group choreography.</jats:p

Beyond Disentangled Representations: An Attentive Angular Distillation Approach to Large-scale Lightweight Age-Invariant Face Recognition

Disentangled representations have been commonly adopted to Age-invariant Face Recognition (AiFR) tasks. However, these methods have reached some limitations with (1) the requirement of large-scale face recognition (FR) training data with age labels, which is limited in practice; (2) heavy deep network architecture for high performance; and (3) their evaluations are usually taken place on age-related face databases while neglecting the standard large-scale FR databases to guarantee its robustness. This work presents a novel Attentive Angular Distillation (AAD) approach to Large-scale Lightweight AiFR that overcomes these limitations. Given two high-performance heavy networks as teachers with different specialized knowledge, AAD introduces a learning paradigm to efficiently distill the age-invariant attentive and angular knowledge from those teachers to a lightweight student network making it more powerful with higher FR accuracy and robust against age factor. Consequently, AAD approach is able to take the advantages of both FR datasets with and without age labels to train an AiFR model. Far apart from prior distillation methods mainly focusing on accuracy and compression ratios in closed-set problems, our AAD aims to solve the open-set problem, i.e. large-scale face recognition. Evaluations on LFW, IJB-B and IJB-C Janus, AgeDB and MegaFace-FGNet with one million distractors have demonstrated the efficiency of the proposed approach. This work also presents a new longitudinal face aging (LogiFace) database for further studies in age-related facial problems in future.Comment: arXiv admin note: substantial text overlap with arXiv:1905.1062

Of Roots and Fruits: A Comparison of Psychedelic and Nonpsychedelic Mystical Experiences

Experiences of profound existential or spiritual significance can be triggered reliably through psychopharmacological means using psychedelic substances. However, little is known about the benefits of religious, spiritual, or mystical experiences (RSMEs) prompted by psychedelic substances, as compared with those that occur through other means. In this study, 739 self-selected participants reported the psychological impact of their RSMEs and indicated whether they were induced by a psychedelic substance. Experiences induced by psychedelic substances were rated as more intensely mystical ( d = .75, p &lt; .001), resulted in a reduced fear of death ( d = .21, p &lt; .01), increased sense of purpose ( d = .18, p &lt; .05), and increased spirituality ( d = .28, p &lt; .001) as compared with nonpsychedelically triggered RSMEs. These results remained significant in an expanded model controlling for gender, education, socioeconomic status, and religious affiliation. These findings lend support to the growing consensus that RSMEs induced with psychedelic substances are genuinely mystical and generally positive in outcome. </jats:p

Antibiotic use and prescription and its effects on Enterobacteriaceae in the gut in children with mild respiratory infections in Ho Chi Minh City, Vietnam. A prospective observational outpatient study.

BACKGROUND AND OBJECTIVES: Treatment guidelines do not recommend antibiotic use for acute respiratory infections (ARI), except for streptococcal pharyngitis/tonsillitis and pneumonia. However, antibiotics are prescribed frequently for children with ARI, often in absence of evidence for bacterial infection. The objectives of this study were 1) to assess the appropriateness of antibiotic prescriptions for mild ARI in paediatric outpatients in relation to available guidelines and detected pathogens, 2) to assess antibiotic use on presentation using questionnaires and detection in urine 3) to assess the carriage rates and proportions of resistant intestinal Enterobacteriaceae before, during and after consultation. MATERIALS AND METHODS: Patients were prospectively enrolled in Children's Hospital 1, Ho Chi Minh City, Vietnam and diagnoses, prescribed therapy and outcome were recorded on first visit and on follow-up after 7 days. Respiratory bacterial and viral pathogens were detected using molecular assays. Antibiotic use before presentation was assessed using questionnaires and urine HPLC. The impact of antibiotic usage on intestinal Enterobacteriaceae was assessed with semi-quantitative culture on agar with and without antibiotics on presentation and after 7 and 28 days. RESULTS: A total of 563 patients were enrolled between February 2009 and February 2010. Antibiotics were prescribed for all except 2 of 563 patients. The majority were 2nd and 3rd generation oral cephalosporins and amoxicillin with or without clavulanic acid. Respiratory viruses were detected in respiratory specimens of 72.5% of patients. Antibiotic use was considered inappropriate in 90.1% and 67.5%, based on guidelines and detected pathogens, respectively. On presentation parents reported antibiotic use for 22% of patients, 41% of parents did not know and 37% denied antibiotic use. Among these three groups, six commonly used antibiotics were detected with HPLC in patients' urine in 49%, 40% and 14%, respectively. Temporary selection of 3rd generation cephalosporin resistant intestinal Enterobacteriaceae during antibiotic use was observed, with co-selection of resistance to aminoglycosides and fluoroquinolones. CONCLUSIONS: We report overuse and overprescription of antibiotics for uncomplicated ARI with selection of resistant intestinal Enterobacteriaceae, posing a risk for community transmission and persistence in a setting of a highly granular healthcare system and unrestricted access to antibiotics through private pharmacies. REGISTRATION: This study was registered at the International Standard Randomised Controlled Trials Number registry under number ISRCTN32862422: http://www.isrctn.com/ISRCTN32862422

Regulatory T cells and their role in rheumatic diseases: a potential target for novel therapeutic development

Regulatory T cells have an important role in limiting immune reactions and are essential regulators of self-tolerance. Among them, CD4+CD25high regulatory T cells are the best-described subset. In this article, we summarize current knowledge on the phenotype, function, and development of CD4+CD25high regulatory T cells. We also review the literature on the role of these T cells in rheumatic diseases and discuss the potential for their use in immunotherapy