Coding sequence alignments of 9,861 mammalian orthologs

The compressed folder contains fasta coding sequence alignments of 9,861 mammalian orthologs. Best reciprocal hits of human Ensembl v69 coding sequences were obtained with Blat for 23 other mammalian species, and those best reciprocal sequences were then aligned with PRANK. Note that best reciprocal hits are not sufficient to establish orthology, and we recommend additional filtering with synteny information

Ultrashort Channel Length Black Phosphorus Field-Effect Transistors

This paper reports high-performance top-gated black phosphorus (BP) field-effect transistors with channel lengths down to 20 nm fabricated using a facile angle evaporation process. By controlling the evaporation angle, the channel length of the transistors can be reproducibly controlled to be anywhere between 20 and 70 nm. The as-fabricated 20 nm top-gated BP transistors exhibit respectable on-state current (174 μA/μm) and transconductance (70 μS/μm) at a <i>V</i>_DS of 0.1 V. Due to the use of two-dimensional BP as the channel material, the transistors exhibit relatively small short channel effects, preserving a decent on–off current ratio of 10² even at an extremely small channel length of 20 nm. Additionally, unlike the unencapsulated BP devices, which are known to be chemically unstable in ambient conditions, the top-gated BP transistors passivated by the Al₂O₃ gate dielectric layer remain stable without noticeable degradation in device performance after being stored in ambient conditions for more than 1 week. This work demonstrates the great promise of atomically thin BP for applications in ultimately scaled transistors

Fully Printed Stretchable Thin-Film Transistors and Integrated Logic Circuits

This paper reports intrinsically stretchable thin-film transistors (TFTs) and integrated logic circuits directly printed on elastomeric polydimethylsiloxane (PDMS) substrates. The printed devices utilize carbon nanotubes and a type of hybrid gate dielectric comprising PDMS and barium titanate (BaTiO₃) nanoparticles. The BaTiO₃/PDMS composite simultaneously provides high dielectric constant, superior stretchability, low leakage, as well as good printability and compatibility with the elastomeric substrate. Both TFTs and logic circuits can be stretched beyond 50% strain along either channel length or channel width directions for thousands of cycles while showing no significant degradation in electrical performance. This work may offer an entry into more sophisticated stretchable electronic systems with monolithically integrated sensors, actuators, and displays, fabricated by scalable and low-cost methods for real life applications

General characteristics of the survey population.

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Multilevel logistic regression analysis of diabetes and glucose intolerance in a community-based, cross-sectional survey of rural adults in Yunnan Province.

<p>OR =  odds ratio.</p><p>CI: confidence interval.</p

Age-and gender-standardized prevalence of diabetes mellitus and glucose intolerance among participants.

<p>Age-and gender-standardized prevalence of diabetes mellitus and glucose intolerance among participants.</p

Air-Stable Humidity Sensor Using Few-Layer Black Phosphorus

As a new family member of two-dimensional layered materials, black phosphorus (BP) has attracted significant attention for chemical sensing applications due to its exceptional electrical, mechanical, and surface properties. However, producing air-stable BP sensors is extremely challenging because BP atomic layers degrade rapidly in ambient conditions. In this study, we explored the humidity sensing properties of BP field-effect transistors fully encapsulated by a 6 nm-thick Al₂O₃ encapsulation layer deposited by atomic layer deposition. The encapsulated BP sensors exhibited superior ambient stability with no noticeable degradation in sensing response after being stored in air for more than a week. Compared with the bare BP devices, the encapsulated ones offered long-term stability with a trade-off in slightly reduced sensitivity. Capacitance–voltage measurement results further reveal that instead of direct charge transfer, the electrostatic gating effect on BP flakes arising from the dipole moment of adsorbed water molecules is the basic mechanism governing the humidity sensing behavior of both bare and encapsulated BP sensors. This work demonstrates a viable approach for achieving air-stable BP-based humidity or chemical sensors for practical applications

Distribution of socioeconomic status among 12 villages.

<p>Distribution of socioeconomic status among 12 villages.</p

A new polyketide glycoside from the rhizospheric <i>Clonostachys rogersoniana</i> associated with <i>Panax notoginseng</i>

<p>A new polyketide glycoside rogerson A (<b>1</b>), along with two known compounds, rogerson B (<b>2</b>) and (22E)-5<i>α</i>,8<i>α</i>-<i>epi</i>dioxyergosta-6,22-dien-3<i>β</i>-ol (<b>3</b>), was obtained from the solid fermentation of <i>Clonostachys rogersoniana</i>, which was isolated from the rhizosphere soil of <i>Panax notoginseng</i>. Rogerson B (<b>2</b>) was isolated for the first time from a natural source. Their structure was determined by extensive analyses of NMR and MS studies. Compounds <b>1</b> and <b>2</b> were tested for its cytotoxicity against five human cancer cell lines.</p

A new C₂₀-diterpenoid alkaloid from the lateral roots of <i>Aconitum carmichaeli</i>

<p>A new C₂₀-diterpenoid alkaloid carmichaedine (<b>1</b>) and six known alkaloids (<b>2</b>–<b>7</b>) were isolated from the lateral roots of <i>Aconitum carmichaeli</i>. Their structures were established on the basis of extensive spectroscopic analyses. Compound <b>1</b> exhibited potent antibacterial activity against <i>Bacillus subtilis</i> with minimum inhibitory concentration of 8 μg/mL.</p