Extended hierarchical search (EHS) algorithm for detection of gravitational waves from inspiraling compact binaries

Pattern matching techniques like matched filtering will be used for online extraction of gravitational wave signals buried inside detector noise. This involves cross correlating the detector output with hundreds of thousands of templates spanning a multi-dimensional parameter space, which is very expensive computationally. A faster implementation algorithm was devised by Mohanty and Dhurandhar [1996] using a hierarchy of templates over the mass parameters, which speeded up the procedure by about 25 to 30 times. We show that a further reduction in computational cost is possible if we extend the hierarchy paradigm to an extra parameter, namely, the time of arrival of the signal. In the first stage, the chirp waveform is cut-off at a relatively low frequency allowing the data to be coarsely sampled leading to cost saving in performing the FFTs. This is possible because most of the signal power is at low frequencies, and therefore the advantage due to hierarchy over masses is not compromised. Results are obtained for spin-less templates up to the second post-Newtonian (2PN) order for a single detector with LIGO I noise power spectral density. We estimate that the gain in computational cost over a flat search is about 100.Comment: 6 pages, 6 EPS figures, uses CQG style iopart.cl

Characterization of multilayer stack parameters from X-ray reflectivity data using the PPM program: measurements and comparison with TEM results

Future hard (10 -100 keV) X-ray telescopes (SIMBOL-X, Con-X, HEXIT-SAT, XEUS) will implement focusing optics with multilayer coatings: in view of the production of these optics we are exploring several deposition techniques for the reflective coatings. In order to evaluate the achievable optical performance X-Ray Reflectivity (XRR) measurements are performed, which are powerful tools for the in-depth characterization of multilayer properties (roughness, thickness and density distribution). An exact extraction of the stack parameters is however difficult because the XRR scans depend on them in a complex way. The PPM code, developed at ERSF in the past years, is able to derive the layer-by-layer properties of multilayer structures from semi-automatic XRR scan fittings by means of a global minimization procedure in the parameters space. In this work we will present the PPM modeling of some multilayer stacks (Pt/C and Ni/C) deposited by simple e-beam evaporation. Moreover, in order to verify the predictions of PPM, the obtained results are compared with TEM profiles taken on the same set of samples. As we will show, PPM results are in good agreement with the TEM findings. In addition, we show that the accurate fitting returns a physically correct evaluation of the variation of layers thickness through the stack, whereas the thickness trend derived from TEM profiles can be altered by the superposition of roughness profiles in the sample image

Support immersion endoscopy in post-extraction alveolar bone chambers: a new window for microscopic bone imaging in Vivo

Using an endoscopic approach, small intraoral bone chambers, which are routinely obtained during tooth extraction and implantation, provide visual in vivo access to internal bone structures. The aim of the present paper is to present a new method to quantify bone microstructure and vascularisation in vivo. Ten extraction sockets and 6 implant sites in 14 patients (6 men / 8 women) were examined by support immersion endoscopy (SIE). After tooth extraction or implant site preparation, microscopic bone analysis (MBA) was performed using short distance SIE video sequences of representative bone areas for off-line analysis with ImageJ. Quantitative assessment of the microstructure and vascularisation of the bone in dental extraction and implant sites in vivo was performed using ImageJ. MBA revealed bone morphology details such as unmineralised and mineralised areas, vascular canals and the presence of bleeding through vascular canals. Morphometric examination revealed that there was more unmineralised bone and less vascular canal area in the implant sites than in the extraction sockets

Can we improve the treatment of congestion in heart failure?

INTRODUCTION: Dyspnoea and peripheral oedema, caused by fluid redistribution to the lungs and/or by fluid overload, are the main causes of hospitalization in patients with heart failure and are associated with poor outcomes. Treatment of fluid overload should relieve symptoms and have a neutral or favorable effect on outcomes. AREAS COVERED: We first consider the results obtained with furosemide administration, which is still the mainstay of treatment of congestion in patients with heart failure. We then discuss important shortcomings of furosemide treatment, including the development of resistance and side effects (electrolyte abnormalities, neurohormonal activation, worsening renal function), as well as the relationship of furosemide - and its doses - with patient prognosis. Finally, the results obtained with potential alternatives to furosemide treatment, including different modalities of loop diuretic administration, combined diuretic therapy, dopamine, inotropic agents, ultrafiltration, natriuretic peptides, vasopressin and adenosine antagonists, are discussed. EXPERT OPINION: Relief of congestion is a major objective of heart failure treatment but therapy remains based on the administration of furosemide, an agent that is often not effective and is associated with poor outcomes. The results of the few controlled studies aimed at the assessment of new treatments to overcome resistance to furosemide and/or to protect the kidney from its untoward effects have been mostly neutral. Better treatment of congestion in heart failure remains a major unmet need

Analysis of a Motocross Knee Brace: From the Real Model to the Numerical Finite Element Model via 3D Scanning and Reverse Engineering

Featured Application: This study outlines a novel procedure for the Finite Element Modelling and Analysis of motocross knee braces under race conditions. The aim is to quantitatively evaluate the effectiveness of such stabilisers in reducing the risk and consequences of musculoskeletal injuries, considering the current lack of industrial standards and dedicated scientific research works. Musculoskeletal injuries often occur when performing motocross; almost half of the overall ligamentous injuries (42%) are knee ligaments injuries. Lesions can be greatly reduced with knee braces. Commercial knee braces are expected to oppose and limit unwanted and potentially harmful movements such as hyperextension and excessive rotation of the knee joint. However, this aspect has not been fully investigated from a biomechanical point of view. This would require proper Finite Element Modelling (FEM) and Analysis (FEA). However, to perform FEA and evaluate the efficacy of the brace simulating sportive conditions, numerical models need to be built. It requires a dedicated setup and several preprocessing steps, for which no industrial standard or widely accepted better practise is available as of today. Firstly, the brace and the lower limb are scanned using a 3D scanner. The geometry is reconstructed using reverse engineering techniques. These allow us to obtain a smooth, reliable 3D model starting from the points cloud acquired during scanning. A lower limb model was created using a mixed approach, combining MRI data and 3D scanning. Finally, a simulation of the impact condition after a jump using the developed model was carried out

Is worsening renal function an ominous prognostic sign in patients with acute heart failure? The role of congestion and its interaction with renal function.

BACKGROUND: Worsening renal function (WRF), traditionally defined as an increase in serum creatinine levels ≥0.3 mg/dL, is a frequent finding in patients with acute heart failure (AHF) and has been associated with poorer outcomes in some but not all studies. We hypothesized that these discrepancies may be caused by the interaction between WRF and congestion in AHF patients. METHODS AND RESULTS: We measured serum creatinine levels on a daily basis during the hospitalization and assessed the persistence of signs of congestion at discharge in 599 consecutive patients admitted at our institute for AHF. They had a postdischarge mortality and mortality or AHF readmission rates of 13% and 43%, respectively, after 1 year. Patients were subdivided into 4 groups according to the development or not of WRF and the persistence of ≥1 sign of congestion at discharge. Patients with WRF and no congestion had similar outcomes compared with those with no WRF and no congestion, whereas the risk of death or of death or AHF readmission was increased in the patients with persistent congestion alone and in those with both WRF and congestion (hazard ratio, 5.35; 95% confidence interval, 3.0-9.55 at univariable analysis; hazard ratio, 2.44; 95% confidence interval, 1.24-4.18 at multivariable analysis for mortality; hazard ratio, 2.14; 95% confidence interval, 1.39-3.3 at univariable analysis; and hazard ratio, 1.39; 95% confidence interval, 0.88-2.2 at multivariable analysis for mortality and rehospitalizations). CONCLUSIONS: WRF alone, when detected using serial serum creatinine measurements, is not an independent determinant of outcomes in patients with AHF. It has an additive prognostic value when it occurs in patients with persistent signs of congestion

Correlation of aligned angular momentum with scattering angle and energy loss in deeply inelastic collisions

..gamma..-ray in-plane to out-of-plane anisotropy and multiplicity are determined for the /sup 100/Mo + /sup 165/Ho reaction at E/sub cm/ = 450 MeV. The measurements are made as functions of Q-value and theta/sub cm/ for the coincident quasi or deeply inelastically scattered ions. Strong correlations of the aligned angular momentum with both energy loss and scattering angle are observed

Deformation Theory of Holomorphic Vector Bundles, Extended Conformal Symmetry and Extensions of 2D Gravity

Developing on the ideas of R. Stora and coworkers, a formulation of two dimensional field theory endowed with extended conformal symmetry is given, which is based on deformation theory of holomorphic and Hermitian spaces. The geometric background consists of a vector bundle $E$ over a closed surface $\Sigma$ endowed with a holomorphic structure and a Hermitian structure subordinated to it. The symmetry group is the semidirect product of the automorphism group ${\rm Aut}(E)$ of $E$ and the extended Weyl group ${\rm Weyl}(E)$ of $E$ and acts on the holomorphic and Hermitian structures. The extended Weyl anomaly can be shifted into an automorphism chirally split anomaly by adding to the action a local counterterm, as in ordinary conformal field theory. The dependence on the scale of the metric on the fiber of $E$ is encoded in the Donaldson action, a vector bundle generalization of the Liouville action. The Weyl and automorphism anomaly split into two contributions corresponding respectively to the determinant and projectivization of $E$. The determinant part induces an effective ordinary Weyl or diffeomorphism anomaly and the induced central charge can be computed.Comment: 49 pages, plain TeX. A number of misprints have been correcte

Transmission Electron Microscopy, High Resolution X-Ray Diffraction and Rutherford Backscattering Study of Strain Release in InGaAs/GaAs Buffer Layers

Strain release and dislocation distribution in InGaAs/GaAs double heterostructures, step-graded and linear-graded buffer layers have been studied. A higher misfit dislocation density at the inner interface between the InGaAs layer and the substrate was found in all the samples. This corresponded to a strain release of the inner ternary layers much larger than predicted by equilibrium theories. The residual parallel strain of the external layers as a function of their thickness was found to follow a curve approximately of slope -0.5, in agreement with previous investigations on single InGaAs layers. This result has been interpreted as evidence that the elastic energy per unit interface area remains constant during the epilayer growth. The presence of numerous single and multiple dislocation loops inside the substrate was attributed to the strain relaxation occurring through dislocation multiplication via Frank-Read sources activated during the growth. A comparison with InGaAs/GaAs step-graded and linear-graded heterostructures is also shown and briefly discussed. Finally, lattice plane tilts between epilayers and substrates have been found due to the imbalance in the linear density of misfit dislocations with opposite component of the Burgers vector, b⊥eff, perpendicular to the interface