26 research outputs found

    Influence of a Pilot Nutrition Education Program on Dietary Knowledge among Undergraduate College Students

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    Objective and Participants: The objective of this study was to determine if a nutrition education program, Everyday Healthy Eating on Campus (EHEC), resulted in positive healthy eating perceptions and behaviors among 103 undergraduates. Methods: Students from eight dormitories (n = 42) and five classrooms (n = 61) completed a shortened Diet and Health Knowledge Survey (DHKS) prior to and one month after EHEC. Another 153 students from eight dormitories (n = 56) and five classrooms (n = 62) were the comparison group. Results: Students that completed EHEC increased their perceived value of eating a diet moderate in salt and sugar, low in saturated fat, adequate in fiber, eating a variety of foods, and consuming a diet with adequate carbohydrate containing foods (p 0.05). Conclusions: A simple one session college nutrition education program focusing on specific campus dining strategies appears to positively affect undergraduate students’ perceived value of healthy eating

    Human N ‐acetylation genotype determination with urinary caffeine metabolites

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/109862/1/cptclpt199059.pd

    Mucosal Tolerance to Aflatoxin B 1 a

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73623/1/j.1749-6632.1996.tb21162.x.pd

    Mucosal unresponsiveness to aflatoxin B1 is not broken by cholera toxin

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    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/142024/1/imcb19978.pd

    A rapid and sensitive screening method for the detection of anti-2-acetylaminofluorene immunoglobulins

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    A method is described in which anti-2-acetylaminofluorene immunoglobulins may be detected using a simple and sensitive screening procedure. The method is based on immunoglobulin binding of an 125I derivatized 2-aminofluorene radiotracer. Tracer binding is not isotype specific, and thus the method is useful for the detection of either IgG or IgA. Competitive binding experiments with the radiotracer were used to determine the specificity of immunoglobulin response by measurement of cross-reactivity with related ligands. This method allows quantitation of the immune response to the carcinogen in serum and other biological fluids (i.e., intestinal secretions).Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/27330/1/0000354.pd

    A matemática financeira no ensino médio : uma nova visão

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    Dissertação (mestrado)—Universidade de Brasília, Instituto de Ciências Exatas, Departamento de Matemática, Programa de Mestrado Profissional em Matemática em Rede Nacional, 2016.Nesse trabalho é apresentada uma proposta para o desenvolvimento da aprendizagem da Matemática Financeira no 3º ano do Ensino Médio por meio da Educação Financeira, utilizando situações cotidianas e focando num resultado mais significativo na vida do educando. O consumismo e a falta de planejamento se tornaram comum na realidade de grande parte da população. Com o advento da globalização e dos programas sociais do Governo Federal, criou-se a possibilidade de pessoas de quaisquer classes sociais terem acesso a bens de consumo, bem como obtenção de créditos com mais facilidade que outrora o teriam, criando um ciclo consumista. O principal objetivo é proporcionar uma nova visão sobre a matemática levando os alunos a refletirem sobre os diversos ângulos em que podem ser mostrados os assuntos de modo a desenvolver nos alunos uma vontade de aprender e avançar no estudo da Matemática Financeira que podem e devem ser aplicadas no dia-a-dia das pessoas.This work has as objective to present a proposal for the learning development of Financial Mathematics of the 3rd year of high school through Financial Education, using everyday situations and focusing in a more significant result in the student’s life. The consumerism and the lack of planning has become a usual reality of the majority of the population. With the advent of globalization and social programs of the Federal Government, it created the possibility of people from any social class to access consumer goods and to obtain credit more easily than before, creating a consumerist cycle. The main objective is to provide a new insight of mathematics leading students to reflect on the various angles that the subjects can be shown in order to develop in students a desire to learn and advance in Financial Mathematics study that can and should be applied on day-by-day lives

    Bromelain Inhibits Allergic Sensitization and Murine Asthma via Modulation of Dendritic Cells

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    The incidence of atopic conditions has increased in industrialized countries. Persisting symptoms and concern for drug side-effects lead patients toward adjunctive treatments such as phytotherapy. Previously, we have shown that Bromelain (sBr), a mixture of cysteine proteases from pineapple, Ananas comosus, inhibits ovalbumin (OVA)-induced murine model of allergic airway disease (AAD). However, sBr’s effect on development of AAD when treatment is administered throughout OVA-alum sensitization was unknown and is the aim of the present study. C57BL/6J mice were sensitized with OVA/alum and challenged with 7 days OVA aerosol. sBr 6 mg/kg/0.5 ml or PBS vehicle were administered throughout sensitization. Lung, bronchoalveolar lavage (BAL), spleen, and lymph nodes were processed for flow cytometry and OVA-specific IgE was determined via ELISA. sBr treatment throughout OVA-alum sensitization significantly reduced the development of AAD (BAL eosinophils and lymphocytes). OVA-specific IgE and OVA TET+ cells were decreased. sBr reduced CD11c+ dendritic cell subsets, and in vitro treatment of DCs significantly reduced CD44, a key receptor in both cell trafficking and activation. sBr was shown to reduce allergic sensitization and the generation of AAD upon antigen challenge. These results provide additional insight into sBr's anti-inflammatory and antiallergic properties and rationale for translation into the clinical arena

    <i>Mycoplasma gallisepticum</i> Lipid Associated Membrane Proteins Up-regulate Inflammatory Genes in Chicken Tracheal Epithelial Cells via TLR-2 Ligation through an NF-κB Dependent Pathway

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    <div><p><i>Mycoplasma gallisepticum</i>-mediated respiratory inflammation in chickens is associated with accumulation of leukocytes in the tracheal submucosa. However the molecular mechanisms underpinning these changes have not been well described. We hypothesized that the initial inflammatory events are initiated upon ligation of mycoplasma lipid associated membrane proteins (LAMP) to TLRs expressed on chicken tracheal epithelial cells (TEC). To test this hypothesis, live bacteria or LAMPs isolated from a virulent (R<sub>low</sub>) or a non-virulent (R<sub>high</sub>) strain were incubated with primary TECs or chicken tracheae <i>ex vivo</i>. Microarray analysis identified up-regulation of several inflammatory and chemokine genes in TECs as early as 1.5 hours post-exposure. Kinetic analysis using RT-qPCR identified the peak of expression for most genes to be at either 1.5 or 6 hours. <i>Ex-vivo</i> exposure also showed up-regulation of inflammatory genes in epithelial cells by 1.5 hours. Among the commonly up-regulated genes were IL-1β, IL-6, IL-8, IL-12p40, CCL-20, and NOS-2, all of which are important immune-modulators and/or chemo-attractants of leukocytes. While these inflammatory genes were up-regulated in all four treatment groups, R<sub>low</sub> exposed epithelial cells both <i>in vitro</i> and <i>ex vivo</i> showed the most dramatic up-regulation, inducing over 100 unique genes by 5-fold or more in TECs. Upon addition of a TLR-2 inhibitor, LAMP-mediated gene expression of IL-1β and CCL-20 was reduced by almost 5-fold while expression of IL-12p40, IL-6, IL-8 and NOS-2 mRNA was reduced by about 2–3 fold. Conversely, an NF-κB inhibitor abrogated the response entirely for all six genes. miRNA-146a, a negative regulator of TLR-2 signaling, was up-regulated in TECs in response to either R<sub>low</sub> or R<sub>high</sub> exposure. Taken together we conclude that LAMPs isolated from both R<sub>high</sub> and R<sub>low</sub> induced rapid, TLR-2 dependent but transient up-regulation of inflammatory genes in primary TECs through an NF-κB dependent pathway.</p></div
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