Coastal Marine Science for Law and Business Students: Preparing Law and Business Professionals to Make Informed Decisions About Coastal Issues

The rigors of employment-directed undergraduate education. and decreased emphasis on Liberal Arts studies occurring at some colleges and universities has left many graduates with a level of scientific understanding which is inadequate to make infonned choices about issues which effect the environment. To address this lack of scientific understanding. the Chesapeake Bay National Estuarine Research Reserve (Virginia) and the Virginia Institute of Marine Science, with the Marshall-Wythe School of Law and the School of Business Administration of the College of William and Mary are developing a Coastal Ecosystem Science Program to teach future law and business professionals the basics of coastal marine science. The Program is being developed after front-end evaluation (telephone survey of law/business faculty members from schools, law and business graduate students and industry professionals from around the United States) which explored the need, successful format, length and other essential or logistical elements of program design. Formative evaluation will continue through student pre-, and post-, testing to evaluate content, information transfer and retention. This program teaches the basic principles of coastal. environmental science to all law and business students (not just those students with experience in environmental science). The goal of this program is to ensure that future lawyers and business leaders will be able to make informed decisions about issues which effect the coastal environment. The development of the program, initial survey and focus group results, essential elements of the program design, evaluation of pilot presentations and plans for pilot-year testing in schools across the country will be discussed

Introduction of cardiotocograph monitoring improves birth outcomes in women with preeclampsia in Ghana

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/135511/1/ijgo103.pd

Far-field pressure measurements of elliptic jets discharged close to a wing

This paper presents a preliminary experimental investigation into the acoustics of two elliptical jet nozzles installed close to a wing model. Acoustic pressure data is obtained for a range of observer polar angles mounted in the far field of the jets. Three nominal jet Mach numbers, namely 0.4, 0.6 and 0.8 are studied. Results suggest that the elliptic jets surveyed provide a noise reduction of the jet-surface installation noise source. The noise reduction is maximum in the forward arc and in the order of 1 dB for the fully-corrected overall sound pressure level data. Additionally, the noise benefit exists only when the minor axis of the elliptical nozzle is mounted parallel to the wing trailing edge. It is hypothesised that the reduction in the jet plume cross-section width limits the scattering of the near pressure field by the wing trailing edge to a lower frequency range. The jet mixing noise source, however, is seen to increase with decreasing nozzle exit-plane aspect ratio. The three jet velocities surveyed suggest the consistency of the key results discussed in the paper. Investigation of the jet turbulent flow structures and jet near pressure field is under way.European Union funding: 76935

Quiver Structure of Heterotic Moduli

We analyse the vector bundle moduli arising from generic heterotic compactifications from the point of view of quiver representations. Phenomena such as stability walls, crossing between chambers of supersymmetry, splitting of non-Abelian bundles and dynamic generation of D-terms are succinctly encoded into finite quivers. By studying the Poincar\'e polynomial of the quiver moduli space using the Reineke formula, we can learn about such useful concepts as Donaldson-Thomas invariants, instanton transitions and supersymmetry breaking.Comment: 38 pages, 5 figures, 1 tabl

Probabilistic movement modeling for intention inference in human-robot interaction.

Intention inference can be an essential step toward efficient humanrobot interaction. For this purpose, we propose the Intention-Driven Dynamics Model (IDDM) to probabilistically model the generative process of movements that are directed by the intention. The IDDM allows to infer the intention from observed movements using Bayes ’ theorem. The IDDM simultaneously finds a latent state representation of noisy and highdimensional observations, and models the intention-driven dynamics in the latent states. As most robotics applications are subject to real-time constraints, we develop an efficient online algorithm that allows for real-time intention inference. Two human-robot interaction scenarios, i.e., target prediction for robot table tennis and action recognition for interactive humanoid robots, are used to evaluate the performance of our inference algorithm. In both intention inference tasks, the proposed algorithm achieves substantial improvements over support vector machines and Gaussian processes.

Transverse optical plasmons in layered superconductors

We discuss the possible existance of transverse optical plasma modes in superlattices consisting of Josephson coupled superconducting layers. These modes appear as resonances in the current-current correlation function, as opposed to the usual plasmons which are poles in the density-density channel. We consider both bilayer superlattices, and single layer lattices with a spread of interlayer Josephson couplings. We show that our model is in quantitative agreement with the recent experimental observation by a number of groups of a peak at the Josephson plasma frequency in the optical conductivity of La$_{1.85}$Sr$_{0.15}$CuO$_4$Comment: Proceedings of LT21, in press, 4 pages, Latex with LTpaper.sty and epsfig.sty, 2 postscript figure

Novel Calcium-Related Targets of Insulin in Hippocampal Neurons

Both insulin signaling disruption and Ca2+ dysregulation are closely related to memory loss during aging and increase the vulnerability to Alzheimer\u27s disease (AD). In hippocampal neurons, aging-related changes in calcium regulatory pathways have been shown to lead to higher intracellular calcium levels and an increase in the Ca2+-dependent afterhyperpolarization (AHP), which is associated with cognitive decline. Recent studies suggest that insulin reduces the Ca2+-dependent AHP. Given the sensitivity of neurons to insulin and evidence that brain insulin signaling is reduced with age, insulin-mediated alterations in calcium homeostasis may underlie the beneficial actions of insulin in the brain. Indeed, increasing insulin signaling in the brain via intranasal delivery has yielded promising results such as improving memory in both clinical and animal studies. However, while several mechanisms have been proposed, few have focused on regulation on intracellular Ca2+. In the present study, we further examined the effects of acute insulin on calcium pathways in primary hippocampal neurons in culture. Using the whole-cell patch-clamp technique, we found that acute insulin delivery reduced voltage-gated calcium currents. Fura-2 imaging was used to also address acute insulin effects on spontaneous and depolarization-mediated Ca2+ transients. Results indicate that insulin reduced Ca2+ transients, which appears to have involved a reduction in ryanodine receptor function. Together, these results suggest insulin regulates pathways that control intracellular Ca2+ which may reduce the AHP and improve memory. This may be one mechanism contributing to improved memory recall in response to intranasal insulin therapy in the clinic

Calcium\u27s Role as Nuanced Modulator of Cellular Physiology in the Brain

Neuroscientists studying normal brain aging, spinal cord injury, Alzheimer’s disease (AD) and other neurodegenerative diseases have focused considerable effort on carefully characterizing intracellular perturbations in calcium dynamics or levels. At the cellular level, calcium is known for controlling life and death and orchestrating most events in between. For many years, intracellular calcium has been recognized as an essential ion associated with nearly all cellular functions from cell growth to degeneration. Often the emphasis is on the negative impact of calcium dysregulation and the typical worse-case-scenario leading inevitably to cell death. However, even high amplitude calcium transients, when executed acutely can alter neuronal communication and synaptic strength in positive ways, without necessarily killing neurons. Here, we focus on the evidence that calcium has a subtle and distinctive role in shaping and controlling synaptic events that underpin neuronal communication and that these subtle changes in aging or AD may contribute to cognitive decline. We emphasize that calcium imaging in dendritic components is ultimately necessary to directly test for the presence of age- or disease-associated alterations during periods of synaptic activation