Scaled-Particle Theory and the Length-scales Involved in Hydrophobic Hydration of Aqueous Biomolecular Assemblies

Hydrophobic hydration plays a crucial role in self-assembly processes over multiple length-scales, but the extrapolation of molecular-scale models to larger length-scale hydration phenomena is sometimes not warranted. Scaled-particle theories are based upon an interpolative view of that issue. We revisit the scaled-particle theory proposed thirty years ago by Stillinger, adopt a practical generalization, and consider the implications for hydrophobic hydration in light of our current understanding. The generalization is based upon identifying a molecular length, implicit in previous applications of scaled-particle models, that provides an effective radius for joining microscopic and macroscopic descriptions. We demonstrate that the generalized theory correctly reproduces many of the anomalous thermodynamic properties of hydrophobic hydration for molecularly sized solutes, including solubility minima and entropy convergence, successfully interpolates between the microscopic and macroscopic extremes, and provides new insights into the underlying molecular mechanisms. The results are discussed in terms of length-scales associated with component phenomena; in particular we first discuss the micro-macroscopic joining radius identified by the theory, then we discuss in turn the Tolman length that leads to an analogous length describing curvature corrections of a surface area model of hydrophobic hydration free energies, and the length-scales on which entropy convergence of hydration free energies are expected.Comment: 19 pages, 14 figures, one figure added, submitted to Rev. Mod. Phy

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Design, fabrication, and evaluation of hand held electron beam gun and external power supply for electron beam welding in spac

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In view of the wide success of molecular quasi-chemical theory of liquids, this paper develops the soft-cutoff version of that theory. This development has important practical consequences in the common cases that the packing contribution dominates the solvation free energy of realistically-modeled molecules because treatment of hard-core interactions usually requires special purpose simulation methods. In contrast, treatment of smooth repulsive interactions is typically straightforward on the basis of widely available software. This development also shows how fluids composed of molecules with smooth repulsive interactions can be treated analogously to the molecular-field theory of the hard-sphere fluid. In the treatment of liquid water, quasi-chemical theory with soft-cutoff conditioning doesn't change the fundamental convergence characteristics of the theory using hard-cutoff conditioning. In fact, hard cutoffs are found here to work better than softer ones.Comment: 5 pages, 2 figure

A Program of Photometric Measurements of Solar Irradiance Fluctuations from Ground-based Observations

Photometric observations of the sun have been carried out at the San Fernando Observatory since early 1985. Since 1986, observations have been obtained at two wavelengths in order to separately measure the contributions of sunspots and bright facular to solar irradiance variations. Researchers believe that the contributions of sunspots can be measured to an accuracy of about plus or minus 30 ppm. The effect of faculae is much less certain, with uncertainties in the range of plus or minus 300 ppm. The larger uncertainty for faculae reflects both the greater difficulty in measuring the facular area, due to their lower contrast compared to sunspots, and the greater uncertainty in their contrast variation with viewing angle on the solar disk. Recent results from two separate photometric telescopes will be compared with bolometric observations from the active cavity radiometer irradiance monitor (ACRIM) that was on board the Solar Max satellite

Three dimensional tracking with misalignment between display and control axes

Human operators confronted with misaligned display and control frames of reference performed three dimensional, pursuit tracking in virtual environment and virtual space simulations. Analysis of the components of the tracking errors in the perspective displays presenting virtual space showed that components of the error due to visual motor misalignment may be linearly separated from those associated with the mismatch between display and control coordinate systems. Tracking performance improved with several hours practice despite previous reports that such improvement did not take place

A proposal for the coherent propagation studies portion of the 10.6-micrometer laser communications experiment Advanced Technology Satellite-F technical proposal

Coherent propagation study proposal for ATS-F 10.6 micrometer laser communications experimen