436 research outputs found

    White trash

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    White Trash, is body of work that aims to reflect upon our personal role and contribution to the solid waste stream through routine consumption and waste disposal. From everything we eat and drink, to the refuse we flush down the drain, we all consume resources. Living in a materially saturated, mass-consumer society, we have evolved into an increasingly disposable culture. By identifying with our waste production, we then can better evaluate the pitfalls of our materialistic ways. Common consumer products stuffed inside a toilet creates a recognizable waste pattern found within the domestic household. Our trash is considered pollution. Once disposed of, our society takes an out of sight, out of mind mentality. Trash receptacles, such as garbage cans and toilets, conveniently offer a sense of freedom from further obligation. Plastic or ceramic containers quell concern for wastes\u27 ultimate destination. By stripping away context and color, I am exposing the sheer volume of waste that we, as individuals, contribute daily. Through this, I raise questions about our current disposable culture

    Human lymphoma mutations reveal CARD11 as the switch between self-antigen-induced B cell death or proliferation and autoantibody production

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    Self-tolerance and immunity are actively acquired in parallel through a poorly understood ability of antigen receptors to switch between signaling death or proliferation of antigenbinding lymphocytes in different contexts. It is not known whether this tolerance-immunity switch requires global rewiring of the signaling apparatus or if it can arise from a single molecular change. By introducing individual CARD11 mutations found in human lymphomas into antigen-activated mature B lymphocytes in mice, we find here that lymphoma-derived CARD11 mutations switch the effect of self-antigen from inducing B cell death into T cell- independent proliferation, Blimp1-mediated plasmablast differentiation, and autoantibody secretion. Our findings demonstrate that regulation of CARD11 signaling is a critical switch governing the decision between death and proliferation in antigen-stimulated mature B cells and that mutations in this switch represent a powerful initiator for aberrant B cell responses in vivo

    Continuity of Lithic Practice from the Eighteenth to the Nineteenth Centuries at the Nipmuc Homestead of Sarah Boston, Grafton, Massachusetts

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    Stone tools have been found at all Nipmuc-related house sites in central Massachusetts dating from the 17th through 20th centuries. This article explores in detail the lithic assemblage recovered from the kitchen midden of the late 18th and early 19th century Sarah Burnee/Sarah Boston farmstead in Grafton, Massachusetts. Quartz and quartzite lithics were found in similar concentrations as historic ceramics within the midden suggesting that these tools were in active use within the household. Ground-stone tools of ancient origin indicate curation and reuse of older materials, and knapped glass and re-worked gunflints suggest knowledge of flintknapping. This article argues that despite colonial rules forbidding traditional Native practices, this and other Nipmuc families continued to practice the production and use of lithics for at least 300 years after the arrival of Europeans

    Multiple health behaviours among mothers and partners in England : clustering, social patterning and intra-couple concordance

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    Research on multiple health behaviours is increasing but little is known about parental behaviours and how they covary. Our study investigates cigarette smoking, alcohol intake, fruit and vegetable (F&V) consumption and physical activity among mothers and co-resident partners in England. Using the UK Household Longitudinal Study, we examined (i) clustering of health behaviours using observed-expected ratios and latent class analysis (ii) socio-demographic correlates of the derived latent classes and (iii) intra-couple concordance of individual health behaviours and their latent classes. We identified five latent classes for mothers and partners: Never smoked drinkers (28% of mothers; 29% of partners), Abstainers (25%; 17%), Drinkers and ex-smokers (19%; 26%), Unhealthy low frequency drinkers (18%; 16%) and Unhealthiest behaviour group (11%; 12%). These had distinctive social profiles. Never smoked drinkers were more likely than those in other groups to be white and socially advantaged: married, older, and with higher educational qualifications and incomes. Abstainers were non-smokers who never or occasionally drank, and were disproportionately drawn from ethnic minority groups and middle/lower income families. Drinkers and ex-smokers were the most physically active group and were more likely to be socially advantaged. Unhealthy low frequency drinkers were more likely to be disadvantaged and have a limiting long-standing illness. The Unhealthiest behaviour group had the highest proportion of smokers, heavy smokers and binge drinkers and the lowest F&V intake and physical activity levels. They were largely white and socially disadvantaged: younger, non-married and with lower educational levels. Mothers and their partners typically shared the same risk behaviours, and 44 per cent of partners and mothers belonged to the same latent class. Our findings point to the potential for a broadening of research and policy perspectives, from separate behaviours to combinations of behaviours, and from individuals to the domestic units and communities of which they are part

    Physical health interventions on adolescent mental health inpatient units : a systematic review and call to action

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    Aim: Physical health inequalities experienced by people with mental health conditions are labelled an international scandal; due to the 15 to 30‐year gap in life expectancy, driven mostly by physical health conditions. Lifestyle interventions are recommended to prevent the onset of poor physical health in people with mental illness. Yet, there is less high‐quality evidence for adolescents, particularly those in inpatient settings. We aimed to assess existing literature reporting physical health or lifestyle interventions conducted on adolescent mental health inpatient units. Method: An electronic search of MEDLINE, PsycINFO, Embase, the Cochrane Central Register of Controlled Trials and AMED was conducted on 13th June 2019. Eligible studies included peer‐reviewed English language research articles of physical health interventions delivered within child and adolescent mental health inpatient services. A narrative synthesis was conducted on the data. Results: Only three studies were identified implementing health interventions for adolescent inpatients. The interventions consisted of two physical health interventions aiming to increase activity levels within routine care (one gym‐based, one sports led) and a yoga intervention. Outcome measurements varied and benefits were observed in relation to overall health (HONOSCA), physical health (waist, hip and chest circumference) and behaviour. Conclusions: Although preliminary results suggest lifestyle interventions may be feasible and beneficial for this group, more work is needed to fully understand the best way to implement these interventions within adolescent clinical settings. Adolescent inpatients are an important target for such interventions, affording the opportunity to prevent the onset of physical comorbidities

    Values as a Driver for Capacity Development: Promoting Justice in Papua New Guinea

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    This case study shows how the Office of the Public Solicitor of Papua New Guinea developed a social change vision built on clearly articulated values and used this as a driver for enhancing both its legitimacy and its capacity more generally. The experience was monitored using the capacity development framework developed by the European Centre for Development Policy and Management. This emphasises individual empowerment and engagement as well as skills, and how these are articulated with collective capabilities in particular contexts to build a system's capacity to perform. The authors suggest that evolution of systemic capacity is a process that requires drivers beyond organisational self interest, personal advantage or greater efficiency. The experience of the OPS shows that capacity can emerge out of fruitful relationships among people holding common ideals who want to make a difference, rather than just resulting from improvements to technique, structure or assets

    The clinical and behavioral cardiometabolic risk of children and young people on mental health inpatient units: A systematic review and meta-analysis

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    Objective: Serious mental illness is associated with physical health comorbidities, however most research has focused on adults. We aimed to synthesise existing literature on clinical and behavioral cardiometabolic risk factors of young people on mental health inpatient units. Methods: A systematic review and meta-analysis was conducted, using electronic searches of PsycINFO, EMBASE, AMED, Cochrane Central Register of Controlled Trials, and Ovid MEDLINE. Eligible studies included child/adolescent mental health inpatient units for 25) was 32.4% (95% CI 26.1%–39.5%; n = 2789), and who were obese (BMI > 30) was 15.5% (95% CI 4.5%–41.6%; n = 2612). Pooled prevalence rates for tobacco use was 51.5% (95% CI 32.2–70.2; N = 804,018). Early signs of metabolic risk were observed; elevated blood cholesterol, presence of physical health conditions, and behavioral risk factors (e.g. physical inactivity). Conclusions: This review highlights the vulnerability of young people admitted to inpatient units and emphasises the opportunity to efficiently monitor, treat and intervene to target physical and mental health

    The Archaeology of Hassanamesit Woods: The Sarah Burnee/Sarah Boston Farmstead

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    Between 2003 and 2013 the Fiske Center for Archaeological Research at the University of Massachusetts Boston conducted an intensive investigation of the Sarah Burnee/Sarah Boston Farmstead on Keith Hill in Grafton, Massachusetts. The project employed a collaborative method that involved working closely with the Town of Grafton, through the Hassanmesit Woods Management Committee, and the Nipmuc Nation, the state recognized government of the Nipmuc people. Yearly excavation and research plans were decided through consultation with both the Nipmuc Tribal Council, their designated representative, Dr. D. Rae Gould, and the Hassanamesit Woods Management Committee. Dr. Gould also played a continuous and active role in reviewing and collaborating on research activities including scholarly presentations at national and international academic meetings and public presentations at the community level. Large scale excavation between 2006 and 2013 focused on the Sarah Burnee/Sarah Boston farmstead that was occupied intensively between 1750 and 1840. Sarah Burnee and Sarah Boston were two of four Nipmuc women to own and possibly reside on the 206 acre parcel that today comprises Hassanamesit Woods. The other two, Sarah Robins and Sarah Muckamaug, were Sarah Burnee’s grandmother and mother respectively. Excavation, archaeogeophysical survey, soil chemistry, and micromorphological and macrobotanical analysis were combined with the analysis of material culture and faunal material to generate a detailed picture of Nipmuc life during the 18th and 19th centuries. Excavation also found evidence of earlier indigenous occupations spanning some 6,000 years. The most intensive period of occupation covered the period 1750 to 1840, but with a significant spike the period 1790 to 1830. This appears to coincide with the coming of age of Sarah Boston who continues to live in the household with her mother Sarah Burnee Philips. Based on a combination of the documentary, architectural and archaeological data, it seems that an addition was made the structure between 1799 and 1802. A rich material assemblage of more than 120,000 artifacts was recovered from the site that provides detailed information on cultural practices including foodways, exchange networks, agricultural activities and other work-related activities such as basket making. A wealth of foodways related artifacts as well as faunal and floral remains provide ample evidence of daily meals and feasting. The latter conclusion is particularly important because of the implications is has for demonstrating that the Hassanamisco Nipmuc were regularly engaged in political activities. We believe the findings of the project provide empirical evidence that counters arguments made by the Bureau of Indian Affairs that the Hassanamisco Nipmuc did not persist as a politically and culturally continuous community
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