718 research outputs found
Still’s-like Disease Induced by Breast Implants in a Middle-Aged Female Health Professional
We report a case of silicone-induced Still’s-like inflammatory syndrome diagnosed after extensive investigation in the department of internal medicine of a secondary hospital. A 45-year-old female healthcare specialist presented with fever, headache, sore throat, myalgia and fatigue. A history of breast augmentation surgery in 2007 was confirmed. Physical examination of the patient was normal while laboratory tests showed a very high white blood cell count. The patient was admitted to hospital due to suspected infection and further laboratory tests were carried out. Inflammatory markers were persistently high despite empirical treatment with doxycycline for possible infection by Rickettsia/Coxiella. As the fever did not resolve and the patient had not improved after more than 3 weeks, the case was investigated as fever of unknown origin. Eventually, the existence of liver granulomas as well as the presence of anti-silicone antibodies confirmed the diagnosis of silicone-induced Still’s-like inflammatory syndrome. In conclusion, this case supports a linkage between silicone breast implants and autoimmune connective tissue diseases
Seeking creativity: A case study on information problem solving in professional music
This study explored the information seeking behavior of a professional jazz musician during creative work. It aimed at revealing information seeking activities necessary to execute present-day musical projects. A single case was studied in depth. First, a narrative interview was conducted to reveal project phases and corresponding information seeking behavior. Second, hereupon a semi-structured interview was taken to identify information seeking activities per phase. Results indicate that the musician deliberately searched for musical information especially in the first project phases. The internet was used as main source. Both data and goal driven strategies were applied, of which the latter were relatively scarce. This means that in this case the musician sporadically searched information based on a contemplated search plan. Future research should aim at generalizing findings of this case. It should further validate the underlying analytical framework that proved to be useful for describing and categorizing musical information seeking behavior
Disconnection clauses: an inevitable symptom of regionalism?
‘Disconnection clauses’ are legal provisions inserted into multilateral conventions to ensure that certain parties to the convention are not required to apply the rules of the convention because other relevant rules have already been agreed to among themselves. A disconnection clause can also be described more generally as a ‘conflict clause’ because it signals to all parties that parallel and potentially conflicting treaty obligations exist.
This paper presents a discussion of the disconnection clause which argues that while these clauses make it possible for a limited group of parties to enhance the objectives of a treaty by taking measures that correspond to their special circumstance, this practice also creates a possibility that the inter se agreement will undermine the original treaty regime. The actual impact of a particular disconnection clause depends on how the clause is crafted, along with the changing nature of the regime that it refers to. The potential for a disconnection clause to undermine the object and purpose of the original treaty can therefore be removed during its design. Nevertheless, without full disclosure when negotiating the convention, any clause that seeks to replace treaty provisions with an alternative regime that would be applicable only between certain parties may, at worst, be creating different standards for different parties and, at best, be opaque and incoherent.
This paper first describes the various types of disconnection clause, focusing on their purpose and development. It then assesses the main legal and political controversies surrounding these clauses before assessing whether these clauses could potentially create more legal problems than they are intended to solve or whether they are simply a practical response to deepening regionalism
Phylogeny of the plant genus Pachypodium (Apocynaceae)
Background. The genus Pachypodium contains 21 species of succulent, generally spinescent shrubs and trees found in southern Africa and Madagascar. Pachypodium has diversified mostly into arid and semi-arid habitats of Madagascar, and has been cited as an example of a plant group that links the highly diverse arid-adapted floras of Africa and Madagascar. However, a lack of knowledge about phylogenetic relationships within the genus has prevented testing of this and other hypotheses about the group.Methodology/Principal Findings. We use DNA sequence data from the nuclear ribosomal ITS and chloroplast trnL-F region for all 21 Pachypodium species to reconstruct evolutionary relationships within the genus. We compare phylogenetic results to previous taxonomic classifications and geography. Results support three infrageneric taxa from the most recent classification of Pachypodium, and suggest that a group of African species (P. namaquanum, P. succulentum and P. bispinosum) may deserve taxonomic recognition as an infrageneric taxon. However, our results do not resolve relationships among major African and Malagasy lineages of the genus.Conclusions/Significance. We present the first molecular phylogenetic analysis of Pachypodium. Our work has revealed five distinct lineages, most of which correspond to groups recognized in past taxonomic classifications. Our work also suggests that there is a complex biogeographic relationship between Pachypodium of Africa and Madagascar
DNA-Profiling and information technology:A new weapon for crime detection and prevention?
Since DNA-profiling involves complicated micro-biological issues, it is imperative to have an understanding of what DNA is and how the DNA-profiling is conducted. Therefore, in the first part the author will very briefly explain what DNA is and how the DNA-profiling is performed. In the second part, the issue is discussed whether the DNAprofiling can be a new wonder weapon for crime prevention and detection in general. For this purpose author outlines the legal status of DNA- profiling in various countries. Thereafter, the impact that DNA-profiling can and will have in conjunction with information technology on crime prevention and privacy rights will be analyzed. At the end the article will give an outlook to future developments and some critical remarks about DNA-profiling in general This article was previously published in European Journal of Crime, Criminal Law and Criminal Justice 1994,issue 4, pp. 359-37
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