Gene array and real time PCR analysis of the adrenal sensitivity to adrenocorticotropic hormone in pig-1

Reated (control) or 1 hour after injection (ACTH) of a high dose (250 μg per animal) of 1–24 ACTH (Immediate synacthen). (n = 6 per experimental group, means ± SE).<p><b>Copyright information:</b></p><p>Taken from "Gene array and real time PCR analysis of the adrenal sensitivity to adrenocorticotropic hormone in pig"</p><p>http://www.biomedcentral.com/1471-2164/9/101</p><p>BMC Genomics 2008;9():101-101.</p><p>Published online 27 Feb 2008</p><p>PMCID:PMC2289818.</p><p></p

Gene array and real time PCR analysis of the adrenal sensitivity to adrenocorticotropic hormone in pig-0

Reated (control) or 1 hour after injection (ACTH) of a high dose (250 μg per animal) of 1–24 ACTH (Immediate synacthen). (n = 6 per experimental group, means ± SE).<p><b>Copyright information:</b></p><p>Taken from "Gene array and real time PCR analysis of the adrenal sensitivity to adrenocorticotropic hormone in pig"</p><p>http://www.biomedcentral.com/1471-2164/9/101</p><p>BMC Genomics 2008;9():101-101.</p><p>Published online 27 Feb 2008</p><p>PMCID:PMC2289818.</p><p></p

Additional file 1 of Multi-tissue metabolic and transcriptomic responses to a short-term heat stress in swine

Additional file 1. Table of the DEGs identified in the seven tissues. Cutoff for adjusted p-value was fixed at 0.05

Additional file 1 of Handling missing rows in multi-omics data integration: multiple imputation in multiple factor analysis framework

Supplementary figures. Figures S1–S3. (PDF 225 kb

The co-expression network where hubs are highlighted.

<p>The names are also given. The list of hubs is available in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0060045#pone.0060045.s007" target="_blank">Table S1</a>.</p

Summary of the statistical pipeline.

<p>Data are represented in green (expression data and pH), statistical methods are represented in purple, results are represented in red.</p

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Boxplots of the partial correlations between the gene expressions and the pH for each cluster.

<p>Cluster 4 is significantly correlated with the pH phenotype (p-value is equal to 0.001).</p

Moran’s plot of the partial correlation between pH and expression levels in the co-expression network.

<p>Influential nodes are displayed in color and their names are given. Influential genes labeled “H–H” have a strong positive correlation with pH (above the mean) and are linked to genes having a strong positive correlation with pH (above the mean); influential genes labeled “H–L” have a strong positive correlation with pH (above the mean) and are linked to genes having a strong negative correlation with pH (below the mean); influential genes labeled “L–H” have a strong negative correlation with pH (below the mean) and are linked to genes having a strong positive correlation with pH (above the mean); influential genes labeled “L–L” have a strong negative correlation with pH (below the mean) and are linked to genes having a strong negative correlation with pH (below the mean). Genes in red are in cluster 4, the cluster that is the most correlated to pH.</p

Correspondence between clusters found by node clustering and bibliographic network.

<p>The list of genes for each cluster was submitted to IPA software and only one biological network was obtained. The eligible genes are those with a gene name accepted by IPA for having biological functions. An average of 83% of the eligible genes were included in the same network. IPA gives also the top biological functions associated with each cluster.</p