42 research outputs found
Modeling flexibility in energy systems : comparison of power sector models based on simplified test cases
Model-based scenario analyses of future energy systems often come to deviating results and conclusions when different models are used. This may be caused by heterogeneous input data and by inherent differences in model formulations. The representation of technologies for the conversion, storage, use, and transport of energy is usually stylized in comprehensive system models in order to limit the size of the mathematical problem, and may substantially differ between models. This paper presents a systematic comparison of nine power sector models with sector coupling. We analyze the impact of differences in the representation of technologies, optimization approaches, and further model features on model outcomes. The comparison uses fully harmonized input data and highly simplified system configurations to isolate and quantify model-specific effects. We identify structural differences in terms of the optimization approach between the models. Furthermore, we find substantial differences in technology modeling primarily for battery electric vehicles, reservoir hydro power, power transmission, and demand response. These depend largely on the specific focus of the models. In model analyses where these technologies are a relevant factor, it is therefore important to be aware of potential effects of the chosen modeling approach. For the detailed analysis of the effect of individual differences in technology modeling and model features, the chosen approach of highly simplified test cases is suitable, as it allows to isolate the effects of model-specific differences on results. However, it strongly limits the model's degrees of freedom, which reduces its suitability for the evaluation of fundamentally different modeling approaches
Interaction between the GROWTH-REGULATING FACTOR and KNOTTED1-LIKE HOMEOBOX families of transcription factors
KNOTTED1-LIKE HOMEOBOX (KNOX) genes are important regulators of meristem function, and a complex network of transcription factors ensures tight control of their expression. Here, we show that members of the GROWTH-REGULATING FACTOR (GRF) family act as players in this network. A yeast (Saccharomyces cerevisiae) one-hybrid screen with the upstream sequence of the KNOX gene Oskn2 from rice (Oryza sativa) resulted in isolation of OsGRF3 and OsGRF10. Specific binding to a region in the untranslated leader sequence of Oskn2 was confirmed by yeast and in vitro binding assays. ProOskn2:β-glucuronidase reporter expression was down-regulated by OsGRF3 and OsGRF10 in vivo, suggesting that these proteins function as transcriptional repressors. Likewise, we found that the GRF protein BGRF1 from barley (Hordeum vulgare) could act as a repressor on an intron sequence in the KNOX gene Hooded/Barley Knotted3 (Bkn3) and that AtGRF4, AtGRF5, and AtGRF6 from Arabidopsis (Arabidopsis thaliana) could repress KNOTTED-LIKE FROM ARABIDOPSIS THALIANA2 (KNAT2) promoter activity. OsGRF overexpression phenotypes in rice were consistent with aberrant meristematic activity, showing reduced formation of tillers and internodes and extensive adventitious root/shoot formation on nodes. These effects were associated with down-regulation of endogenous Oskn2 expression by OsGRF3. Conversely, RNA interference silencing of OsGRF3, OsGRF4, and OsGRF5 resulted in dwarfism, delayed growth and inflorescence formation, and up-regulation of Oskn2. These data demonstrate conserved interactions between the GRF and KNOX families of transcription factors in both monocot and dicot plants
Model-related outcome differences in power system models with sector coupling - quantification and drivers
This paper presents the results of a multi-model comparison to determine outcome deviations resulting from differences in power system models. We apply eight temporally and spatially resolved models to 16 stylized test cases. These test cases differ in their renewable energy supply share, technology scope, and optimization scope. We focus on technologies for balancing the variability of power generation, such as controllable power plants, energy storage, power transmission, and flexibility related to sector coupling. We use harmonized input data in all models to separate model-related from data-related outcome deviations. We find that our approach allows for isolating and quantifying model-related outcome deviations and robust effects concerning system operation and investment decisions. Furthermore, we can attribute these deviations to the identified model differences. Our results show that trends in the use of individual flexibility options are robust across most models. Moreover, our analysis reveals that differences in the general modeling approach and the modeling of specific technologies lead to comparatively small deviations. In contrast, a heterogeneous model scope can cause substantially larger deviations. Due to a large number of models and scenarios, our analysis can provide important information on which investment and operation decisions are robust to the model choice, and which modeling approaches have an exceptionally high impact on results. Our findings may guide both modelers and decision-makers in properly evaluating the results of similarly designed power system models
Impacts of power sector model features on optimal capacity expansion: a comparative study
The transition towards decarbonized energy systems requires the expansion of renewable and flexibility technologies in power sectors. Many powerful tools exist to find optimal capacity expansion. In a stylized comparison of six models, we evaluate the capacity expansion results of basic power sector technologies. The technologies under investigation include base- and peak-load power plants, electricity storage, and transmission. We define four highly simplified and harmonized test cases that focus on the expansion of only one or two specific technologies to isolate their effects on model results. We find that deviating assumptions on limited availability factors of technologies cause technology-specific deviations between optimal capacity expansion in models in almost all test cases. Fixed energy-to-power-ratios of storage can entirely change model optimal expansion outcomes, especially shifting the ratio between short- and long-duration storage. Fixed initial and end storage levels can impact the seasonal use of long-duration storage. Models with a pre-ordered dispatch structure substantially deviate from linear optimization models, as missing foresight and limited flexibility can lead to higher capacity investments. A simplified net transfer capacity approach underestimates the need for grid infrastructure compared to a more detailed direct current load flow approach. We further find deviations in model results of optimal storage and transmission capacity expansion between regions and link them to variable renewable energy generation and demand characteristics. We expect that the general effects identified in our stylized setting also hold in more detailed model applications, although they may be less visible there
Verbundvorhaben FlexMex: Modellexperiment zur zeitlich und räumlich hoch aufgelösten Untersuchung des zukünftigen Lastausgleichs im Stromsystem
Das Projekt FlexMex konzentrierte sich auf einen Modellvergleich zur Untersuchung der Nutzung von Flexibilitätsoptionen zum Ausgleich der Stromerzeugung aus variablen erneuerbaren Energien. Die zentrale Frage war, wie unterschiedliche Optimierungs- und Technologiemodellie-rungsansätze den Anlageneinsatz in stündlich aufgelösten Stromsektormodellen beeinflussen. Darüber hinaus wurde der Einfluss unterschied-licher Modellumfänge auf den Einsatz von Flexibilitätsoptionen untersucht. Um datenbedingte von modellbedingten Unterschieden in den Ergebnissen konsequent zu trennen, wurden die Eingangsdaten der neun beteiligten Modelle vollständig harmonisiert. Die Anwendung der Modelle wurde dann in zwei Hauptexperimente unterteilt. Im ersten Experiment wurden auf der Grundlage einer umfassenden qualitativen Analyse der Modelle und ihrer Unterschiede einzelne Flexibilitätsoptionen untersucht. Anhand stark reduzierter Testfälle konnten modellspe-zifische Effekte isoliert und quantifiziert werden. Ergänzende Analysen befassten sich mit dem modellendogenen Ausbau von Stromspeichern, Stromnetzen und regelbaren Kraftwerken. Aufbauend auf den technologiespezifischen Analysen wurden im zweiten Modellexperiment komplexere Szenarien betrachtet. Dort wurden sechzehn stilisierte Szenarien betrachtet, die sich in Versorgungsanteil erneuerbarer Ener-gien, Technologieumfang und Optimierungsumfang unterscheiden. Trotz der hohen Anzahl der Modelle und der interagierenden Modellun-terschiede können die Ergebnisabweichungen auf die Modelleigenschaften zurückgeführt werden. Das Experiment zeigt, dass Unterschiede im Modellierungsansatz und der Technologieabbildung zu vergleichsweise geringen Abweichungen führen, während ein heterogener Modell-umfang einen deutlich größeren Einfluss haben kann. Zusammenfassend können die Ergebnisse des FlexMex-Projekts ein besseres Verständ-nis für die Wirkung unterschiedlicher Modellierungsansätze liefern und damit zur Interpretation von Modellergebnissen beitragen
Implications of serial measurements of natriuretic peptides in heart failure: insights from BIOSTAT‐CHF
No abstract available
The effect of intrathecal baclofen treatment on activities of daily life in children and young adults with cerebral palsy and progressive neurological disorders
Introduction Intrathecal baclofen (ITB) treatment is applied in patients with spastic cerebral palsy (SCP), dystonic cerebral palsy (DCP) and progressive neurological disease (PND). Our aim was to investigate whether ITB treatment has a different effect on activities of daily life (ADL) in these groups. Method A retrospective and cross-sectional survey was conducted using a questionnaire to assess the qualitative effect of ITB (Likert scale) on different domains of functioning (mobility, personal care, communication, comfort) and satisfaction with the results. Groups were compared using non-parametric statistics. Results Questionnaires were completed for 68 patients (39 SCP, 13 DCP, 16 PND). Satisfaction scores were relatively high in all groups (7–8) and the positive effect on personal care and communication was similar in all groups. The PND group had the shortest follow-up and scored significantly less favourably for the effect on mobility and comfort. Discussion This is the first study to show that ITB treatment has similar effects on personal care and communication in stable and progressive neurological disease. The decrease in mobility in the PND group is likely due to the progressive nature of the disease. The different effect on comfort between groups is mainly due to the smaller effect on startles in the PND group
Evolution of gait in adolescents and young adults with spastic diplegia after selective dorsal rhizotomy in childhood: A 10 year follow-up study
Background: Short-term benefit on gait of selective dorsal rhizotomy (SDR) surgery, which relieves spasticity of the lower extremities has been demonstrated in children with cerebral palsy (CP). However very little is known of the evolution of gait when patients become adolescents and young adults. Research question: How does the gait pattern evolve in adolescents and young adults who underwent SDR during childhood? Methods: A longitudinal study was performed including 19 ambulant patients with spastic diplegia due to CP or other causes (mean age at SDR: 6.6 ± 1.6 years) who were assessed four times: pre-SDR, 2 years post- SDR, 5 years post-SDR and at least 10 years post-SDR. From 2D video recordings, Edinburgh Visual Gait Score and lower limb joint kinematic parameters were calculated. Results: Our data show that the improvement in the gait pattern obtained short-term after SDR continues during into adolescence and adulthood. Ten years after SDR all patients improved compared to baseline. Considering the lower limb joint kinematics, most notable improvements were found at knee and ankle joints. Compared to the evaluation before SDR, the range of motion of the knee increased: the knee was more extended at initial contact and knee flexion in midswing improved. Excessive ankle plantar flexion was reduced during the entire gait cycle. Only minor changes were found at hip and pelvis. Eight patients underwent additional orthopaedic surgery in the years after SDR, and the present findings should be considered as a combination of SDR, development and additional treatment. Significance: We demonstrate lasting improvement of gait quality in ambulant patients with spastic diplegia who underwent SDR during childhood when they become adolescents and young adults
Model-related outcome differences in power system models with sector coupling - quantification and drivers
This paper presents the results of a multi-model comparison to determine outcome deviations resulting from differences in power system models. We apply eight temporally and spatially resolved models to 16 stylized test cases. These test cases differ in their renewable energy supply share, technology scope, and optimization scope. We focus on technologies for balancing the variability of power generation, such as controllable power plants, energy storage, power transmission, and flexibility related to sector coupling. We use harmonized input data in all models to separate model-related from data-related outcome deviations. We find that our approach allows for isolating and quantifying model-related outcome deviations and robust effects concerning system operation and investment decisions. Furthermore, we can attribute these deviations to the identified model differences. Our results show that trends in the use of individual flexibility options are robust across most models. Moreover, our analysis reveals that differences in the general modeling approach and the modeling of specific technologies lead to comparatively small deviations. In contrast, a heterogeneous model scope can cause substantially larger deviations. Due to a large number of models and scenarios, our analysis can provide important information on which investment and operation decisions are robust to the model choice, and which modeling approaches have an exceptionally high impact on results. Our findings may guide both modelers and decision-makers in properly evaluating the results of similarly designed power system models