Sustainability and the politics of calculation: technologies of 'safe water,' subject-making, and domination

This paper critically examines sustainability as an ideology that gives meaning to processes of domination occurring through the operations of treated water systems in Iñupiaq villages in Alaska's Northwest. The implementation of neoliberal sustainability policies shapes social relations around water, establishes particular forms of 'expert' knowledge, erases experiences of water insecurity, and renders moot local opposition to charging for water. Throughout, treated 'safe water' is signified as a scarce commodity; its production requiring full cost recovery through practices of calculation that discipline Iñupiaq citizens as consumers. This paper provides a case study for understanding some of the processes of domination through which the commodification of water occurs, and how local people who otherwise oppose these processes may nonetheless become drawn into practices of calculation and domination in an attempt to meet state-defined sustainability requirements. Key words: Sustainability, water insecurity, domination, Alaska Native

Breast injury during sport participation

A recent study found that almost half (47.9%), of female college athletes participating in basketball, soccer, volleyball and softball (n = 194) suffered a breast injury during their college career with less than 10% reporting their injury to health personnel with only 2.1% receiving treatment [1]. Breast injury in female athletes is under-reported and is lacking a much-needed level of awareness in sport. If there is a void in awareness of breast injuries and in reporting breast injuries, preventive measures as well as any potential sequela from the injury will not be given the necessary attention

“Remoteness was a blessing, but also a potential downfall”: Traditional/Subsistence and store-bought food access in remote Alaska during the COVID-19 pandemic

Abstract Objective: This study employs a strengths-based approach to assess food access in remote Alaska during the COVID-19 pandemic, identifying both the negative consequences of the pandemic on store-bought and subsistence/traditional food access as well as compensatory strategies used. Design: As a part of a larger study on the impacts of COVID-19 on daily life remote Alaska communities, study data presented here were collected through key informant interviews (KIIs) and statewide online surveys from September 21, 2020 to March 31, 2021 among remote Alaska community members. Setting: This study was conducted with residents of remote communities in Alaska, defined as those off of the road system. Remote communities often have small or no grocery stores, and rely on subsistence or traditional sources of food. Participants: KII participants (n=36) were majority female (78%) and Alaska Native (57%). Survey participants (n=615) were also majority female, 25-54 years old, and most had had some post-secondary education or training. Results: Survey and interview data revealed that the pandemic had significant negative impacts on store-bought food access in remote Alaskan communities. Individuals also shared that locally available and wild harvested foods acted as a buffer to some of the loss of access to these store-bought foods, with some people sharing that the harvesting of wild and traditional foods served served as a coping strategy during times of pandemic-related stress. Conclusions: The results from this study demonstrate that the remoteness of some Alaska communities has been both a source of vulnerability and protection in terms food access

Advancing human capabilities for water security: A relational approach

We argue that a relational water security framework informed by the capabilities approach offers new ways to consider politics and cultures of water. Each dimension allows us to better contextualize water security beyond just an object (H2O) to be secured for a certain population. Instead, the relational perspective demands a fuller consideration of the political structures and processes through which water is secured, with emphasis on the social relations of access as opposed to simply the politics around water supply. We also attend to cultural dimensions, such as the meanings of water and customary practices that are not easily captured by standardized metrics. By including these dimensions, we necessarily broaden analytical space to evaluate water security as a relational and dynamic process tied to lived experience rather than as solely parameterized conditions in relation to access, quality, or availability of water. We first move to explain our broader conceptualization of water security as linked to human capabilities, then explore in more detail the specific engagements with politics and culture in the sections that follow

Comparability of neuraminidase inhibition antibody titers measured by enzyme-linked lectin assay (ELLA) for the analysis of influenza vaccine immunogenicity

AbstractNeuraminidase-inhibition (NI) antibody titers can be used to evaluate the immunogenicity of inactivated influenza vaccines and have provided evidence of serologic cross-reactivity between seasonal and pandemic H1N1 viruses. The traditional thiobarbituric acid assay is impractical for large serologic analyses, and therefore many laboratories use an enzyme-linked lectin assay (ELLA) to determine serum NI antibody titers. The comparability of ELLA NI antibody titers when measured in different laboratories was unknown. Here we report a study conducted through the Consortium for the Standardisation of Influenza SeroEpidemiology (CONSISE) to evaluate the variability of the ELLA. NI antibody titers of a set of 12 samples were measured against both N1 and N2 neuraminidase antigens in 3 independent assays by each of 23 laboratories. For a sample repeated in the same assay, ≥96% of N1 and N2 assays had less than a 4-fold difference in titer. Comparison of the titers measured in assays conducted on 3 different days in the same laboratory showed that a four-fold difference in titer was uncommon. Titers of the same sera measured in different laboratories spanned 3 to 6 two-fold dilutions (i.e., 8–64 fold difference in titer), with an average percent geometric coefficient of variation (%GCV) of 112 and 82% against N1 and N2 antigens, respectively. The difference in titer as indicated by fold range and %GCV was improved by normalizing the NI titers to a standard that was included in each assay. This study identified background signal and the amount of antigen in the assay as critical factors that influence titer, providing important information toward development of a consensus ELLA protocol

Hepatocyte expressed chemerin-156 does not protect from experimental non-alcoholic steatohepatitis.

Non-alcoholic steatohepatitis (NASH) is a rapidly growing liver disease. The chemoattractant chemerin is abundant in hepatocytes, and hepatocyte expressed prochemerin protected from NASH. Prochemerin is inactive and different active isoforms have been described. Here, the effect of hepatocyte expressed muChem-156, a highly active murine chemerin isoform, was studied in the methionine-choline deficient dietary model of NASH. Mice overexpressing muChem-156 had higher hepatic chemerin protein. Serum chemerin levels and the capability of serum to activate the chemerin receptors was unchanged showing that the liver did not release active chemerin. Notably, activation of the chemerin receptors by hepatic vein blood did not increase in parallel to total chemerin protein in patients with liver cirrhosis. In experimental NASH, muChem-156 had no effect on liver lipids. Accordingly, overexpression of active chemerin in hepatocytes or treatment of hepatocytes with recombinant chemerin did not affect cellular triglyceride and cholesterol levels. Importantly, overexpression of muChem-156 in the murine liver did not change the hepatic expression of inflammatory and profibrotic genes. The downstream targets of chemerin such as p38 kinase were neither activated in the liver of muChem-156 producing mice nor in HepG2, Huh7 and Hepa1-6 cells overexpressing this isoform. Recombinant chemerin had no effect on global gene expression of primary human hepatocytes and hepatic stellate cells within 24 h of incubation. Phosphorylation of p38 kinase was, however, increased upon short-time incubation of HepG2 cells with chemerin. These findings show that muChem-156 overexpression in hepatocytes does not protect from liver steatosis and inflammation

MANUFACTURING INSECURITY: POWER, WATER, WASTE, AND THE SILENCES OF SUSTAINABILITY AND SUFFERING IN NORTHWEST ALASKA

With its oil wealth and an environment of abundant rivers, lakes, and the largest coastline in the United States, Alaska is one of the last places one would expect to find water insecurity. Yet approximately one third of households in remote Alaska Native villages lack in-home piped water and suffer the health consequences of poor sanitation and inadequate treated water. This problem has become particularly acute in the wake of surging energy prices and a concomitant shift in policies that increasingly require demonstrated economic sustainability before funding will be allocated for village water and sanitation projects. In response to increasing costs of living and the failure of development projects to foster the conditions under which they would be able to provide for their needs, many Iñupiat assert the importance of traditional values, practices and values that from their view constitute a path out of insecurity and into self-sufficiency. These Iñupiat point to modern technology as the source of what they call the spoiling of their communities. In this dissertation, I explore the disjuncture between how the state and the Iñupiat signify historical and contemporary issues and solutions around water, energy, and development. I suggest that the unintended consequences of decades of interventions to improve Iñupiaq health and well-being have been manufactured insecurity that is exacerbated by weakened social networks of reciprocity (the Iñupiaq traditional value of sharing), and rendered invisible by sustainability policies. I argue that these multifaceted processes of domination and suffering are all part of what many Iñupiat describe spoiling. In other words, when the Iñupiat talk about being spoiled by technology, they are talking about the historical domination by the state over their social reproduction in ways that produce and exacerbate the insecurities characterizing daily life in these remote villages.Dissertation not available (per author's request)previously embargoed until May 2, 2013; restricted on June 3, 2013 per author's request; K

The Politics of an Epidemic: SARS & Chinatown

This thesis explores how the 2003 epidemic of Severe Acute Respiratory Syndrome, or SARS, threw into relief the myriad historical, political and economic factors that shape understandings of and responses to a new disease. The author traces how the historic "othering" of Chinese immigrants and their descendents in the United States was combined with dominant discourses of risk and blame to understand SARS and the potential for a domestic epidemic. Narratives from community members of Manhattan's Chinatown are used to investigate the local impacts of the production of these discourses during the SARS epidemic. Finally, the author explores how these dominant discourses were applied locally within Chinatown understand local and personal risk

SARS and New York's Chinatown: The politics of risk and blame during an epidemic of fear

This paper examines the production of risk and blame discourses during the 2003 SARS epidemic and responses to those messages in New York City's Chinatown, a community stigmatized during the SARS epidemic despite having no SARS cases. The study consisted of 6 weeks participant observation and 37 semi-structured, open-ended interviews with community members. Stigmatizing discourses from the late 19th century resurfaced to blame Chinese culture and people for disease, and were recontextualized to fit contemporary local and global political-economic concerns. Many informants discursively distanced themselves from risk but simultaneously reaffirmed the association of Chinese culture with disease by redirecting such discourses onto recent Chinese immigrants. Legitimizing cultural blame obfuscates the structural and biological causes of epidemics and naturalizes health disparities in marginalized populations. This research demonstrates that myriad historical, political, and economic factors shape responses and risk perceptions during an unfamiliar epidemic, even in places without infection.Risk perceptions SARS United States Stigma Emerging infectious disease Chinese-Americans