2,398 research outputs found

    Securing Financial Resources For Small And Medium Contracting Firms In Malaysia [HD2346.M2 L366 2008 f rb].

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    Penyelidik dalam bidang perusahaan kecil dan sederhana (PKS) sering mendalilkan bahawa PKS mempunyai criteria seperti kekurangan modal dan tidak mendapat pembiayaan perkembangan yang setaraf. Small and medium enterprises (SMEs) researchers often argue that SME are characterised by lack of capital and are unable to access the same kinds of growth funding

    Socioeconomic Status and Parenting Priorities: Child Independence and Obedience Around the World

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    This study investigated the extent to which national and personal socioeconomic status shapes national norms and parenting priorities concerning child socialization. Data came from European Values Survey, World Values Survey, and World Bank Data Catalog, resulting in 227,431 parents from 90 nations across fives study waves (1981-2008). At nation-level, child independence was more popular in nations with greater wealth and higher percentage of educated populations; obedience was more popular in nations with less wealth and lower percentages of educated and urban populations. At person-level, personal socioeconomic status rather than national socioeconomic characteristics predicted individual parents’ prioritization of child independence and obedience; higher social class predicted greater likelihood of endorsing independence and not endorsing obedience. Time slope estimation across study waves revealed that parental prioritization of both independence and obedience expected to rise over time in developing nations. Results provide implications for education, practice, and policy concerning cultural variation in parenting

    Socioeconomic Status and Parenting Priorities: Child Independence and Obedience Around the World

    Get PDF
    This study investigated the extent to which national and personal socioeconomic status shapes national norms and parenting priorities concerning child socialization. Data came from European Values Survey, World Values Survey, and World Bank Data Catalog, resulting in 227,431 parents from 90 nations across fives study waves (1981-2008). At nation-level, child independence was more popular in nations with greater wealth and higher percentage of educated populations; obedience was more popular in nations with less wealth and lower percentages of educated and urban populations. At person-level, personal socioeconomic status rather than national socioeconomic characteristics predicted individual parents’ prioritization of child independence and obedience; higher social class predicted greater likelihood of endorsing independence and not endorsing obedience. Time slope estimation across study waves revealed that parental prioritization of both independence and obedience expected to rise over time in developing nations. Results provide implications for education, practice, and policy concerning cultural variation in parenting

    Anti-tumor necrosis factor-alpha therapy during murine Klebsiella pneumoniae bacteremia: increased mortality in the absence of liver injury.

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    Klebsiella pneumoniae is a leading cause of gram-negative bacterial pneumonia, often resulting in bacteremia concurrent with the localized pulmonary infection. The beneficial role of tumor necrosis factor (TNF)-alpha during pulmonary infection has been well documented; however, consequences of TNF-alpha production during systemic bacterial infection are controversial. A murine model of K. pneumoniae was developed to address this important issue. Liver-associated TNF-alpha mRNA was induced within 30 min after intravenous bacterial inoculation and remained elevated through 6 h before returning to near-baseline at 24 h postinfection. Intravenous K. pneumoniae infection induced liver cellular injury that was completely ablated when mice were pretreated with a neutralizing anti-TNF-alpha antibody. Interestingly, this reduction in liver injury failed to translate into improved survival. Mice receiving anti-TNF-alpha continued to succumb to the infection even out to day 10 postinfection. Bacterial clearance after TNF-alpha neutralization was significantly impaired at later time points during infection. Correlating with impaired bacterial clearance was diminished production of liver-associated MIP-2, MIP-1alpha, MCP-1, and interferon-gamma. Further evidence of diminished antibacterial immune responses was noted when the activational status of splenic natural killer cells in anti-TNF-alpha-treated mice was examined 24 h postinfection. Natural killer cells displayed decreased CD69 expression. Combined, these data indicate that the beneficial effects of TNF-alpha during systemic K. pneumoniae infection outweigh the detrimental effects of TNF-alpha-mediated hepatocyte cellular injury. Anti-TNF-alpha therapy, although preventing liver injury during blood-borne bacterial infection, results in a dampened anti-bacterial host response, resulting in decreased bacterial clearance and overall survival
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