Uji Efektivitas Diuretik Ekstrak Etanol Biji Salak (Salacca Zalacca Varietas Zalacca (Gaert.) Voss) Pada Tikus Putih Jantan Galur Wistar (Rattus Norvegicus)

This research has purpose to examine the diuretic effects of Salak seed\u27s ethanol extract and to analyze the relationship of dose concentration of Salak seed\u27s ethanol extract upon diuretic effect on Wistar white male mice (Rattus norvegicus). 15 mice were divided into five different treatment groups, namely: negative control (0.5% CMC suspension), positive control (5.04 mg/kg furosemide suspension), suspension of Salak seed\u27s ethanol extract 0.07 g/KgBB, suspension of Salak seed\u27s ethanol extract 0.14 g/KgBB, and suspensions of ethanol extract of salak seeds 0.28 g/KgBB. The Tests of diuretic effect were conducted by calculate the urine volume which was excreted urine during 6 hours of treatment. The data were analyzed by SPSS ver.20, one way ANOVA test to find out the average difference in each treatment group, if there is significant difference, it is continued with LSD test. The result of LSD test showed that the treatment group of Salak seed\u27s ethanol extract 0.07 g/KgBB didn\u27t give any significant results with CMC 0.5% (negative control) as compared with the treatment group of Salak seed\u27s ethanol extract 0.14 g/KgBB and 0.028 g/KgBB that gave significant results, this means that the higher concentration of Salak seed\u27s ethanol extract is set, the bigger diuretic effect is created