1,222 research outputs found
Cerebral blood flow thresholds for cerebral ischemia in traumatic brain injury. A systematic review
Reading a GEM with a VLSI pixel ASIC used as a direct charge collecting anode
In MicroPattern Gas Detectors (MPGD) when the pixel size is below 100 micron
and the number of pixels is large (above 1000) it is virtually impossible to
use the conventional PCB read-out approach to bring the signal charge from the
individual pixel to the external electronics chain. For this reason a custom
CMOS array of 2101 active pixels with 80 micron pitch, directly used as the
charge collecting anode of a GEM amplifying structure, has been developed and
built. Each charge collecting pad, hexagonally shaped, realized using the top
metal layer of a deep submicron VLSI technology is individually connected to a
full electronics chain (pre-amplifier, shaping-amplifier, sample and hold,
multiplexer) which is built immediately below it by using the remaining five
active layers. The GEM and the drift electrode window are assembled directly
over the chip so the ASIC itself becomes the pixelized anode of a MicroPattern
Gas Detector. With this approach, for the first time, gas detectors have
reached the level of integration and resolution typical of solid state pixel
detectors. Results from the first tests of this new read-out concept are
presented. An Astronomical X-Ray Polarimetry application is also discussed.Comment: 11 pages, 14 figures, presented at the Xth Vienna Conference on
Instrumentation (Vienna, February 16-21 2004). For a higher resolution paper
contact [email protected]
Passato, presente e futuro dei coadiuvanti locali e sistemici nel trattamento non chirurgico di perimplantiti e parodontiti: indicazioni e limiti
Spectral and polarimetric characterization of the Gas Pixel Detector filled with dimethyl ether
The Gas Pixel Detector belongs to the very limited class of gas detectors
optimized for the measurement of X-ray polarization in the emission of
astrophysical sources. The choice of the mixture in which X-ray photons are
absorbed and photoelectrons propagate, deeply affects both the energy range of
the instrument and its performance in terms of gain, track dimension and
ultimately, polarimetric sensitivity. Here we present the characterization of
the Gas Pixel Detector with a 1 cm thick cell filled with dimethyl ether (DME)
at 0.79 atm, selected among other mixtures for the very low diffusion
coefficient. Almost completely polarized and monochromatic photons were
produced at the calibration facility built at INAF/IASF-Rome exploiting Bragg
diffraction at nearly 45 degrees. For the first time ever, we measured the
modulation factor and the spectral capabilities of the instrument at energies
as low as 2.0 keV, but also at 2.6 keV, 3.7 keV, 4.0 keV, 5.2 keV and 7.8 keV.
These measurements cover almost completely the energy range of the instrument
and allows to compare the sensitivity achieved with that of the standard
mixture, composed of helium and DME.Comment: 20 pages, 11 figures, 5 tables. Accepted for publication by NIM
Low energy polarization sensitivity of the Gas Pixel Detector
An X-ray photoelectric polarimeter based on the Gas Pixel Detector has been
proposed to be included in many upcoming space missions to fill the gap of
about 30 years from the first (and to date only) positive measurement of
polarized X-ray emission from an astrophysical source. The estimated
sensitivity of the current prototype peaks at an energy of about 3 keV, but the
lack of readily available polarized sources in this energy range has prevented
the measurement of detector polarimetric performances.
In this paper we present the measurement of the Gas Pixel Detector
polarimetric sensitivity at energies of a few keV and the new, light, compact
and transportable polarized source that was devised and built to this aim.
Polarized photons are produced, from unpolarized radiation generated with an
X-ray tube, by means of Bragg diffraction at nearly 45 degrees.
The employment of mosaic graphite and flat aluminum crystals allow the
production of nearly completely polarized photons at 2.6, 3.7 and 5.2 keV from
the diffraction of unpolarized continuum or line emission. The measured
modulation factor of the Gas Pixel Detector at these energies is in good
agreement with the estimates derived from a Monte Carlo software, which was up
to now employed for driving the development of the instrument and for
estimating its low energy sensitivity. In this paper we present the excellent
polarimetric performance of the Gas Pixel Detector at energies where the peak
sensitivity is expected. These measurements not only support our previous
claims of high sensitivity but confirm the feasibility of astrophysical X-ray
photoelectric polarimetry.Comment: 15 pages, 12 figures. Accepted for publication in NIM
Gleam: the GLAST Large Area Telescope Simulation Framework
This paper presents the simulation of the GLAST high energy gamma-ray
telescope. The simulation package, written in C++, is based on the Geant4
toolkit, and it is integrated into a general framework used to process events.
A detailed simulation of the electronic signals inside Silicon detectors has
been provided and it is used for the particle tracking, which is handled by a
dedicated software. A unique repository for the geometrical description of the
detector has been realized using the XML language and a C++ library to access
this information has been designed and implemented.Comment: 10 pages, Late
High surface area mesoporous silica nanoparticles with tunable size in the sub-micrometer regime: Insights on the size and porosity control mechanisms
Mesoporous silica nanostructures (MSNs) attract high interest due to their unique and tunable physical chemical features, including high specific surface area and large pore volume, that hold a great potential in a variety of fields, i.e., adsorption, catalysis, and biomedicine. An essential feature for biomedical application of MSNs is limiting MSN size in the sub-micrometer regime to control uptake and cell viability. However, careful size tuning in such a regime remains still chal-lenging. We aim to tackling this issue by developing two synthetic procedures for MSN size mod-ulation, performed in homogenous aqueous/ethanol solution or two-phase aqueous/ethyl acetate system. Both approaches make use of tetraethyl orthosilicate as precursor, in the presence of cetyltri-methylammonium bromide, as structure-directing agent, and NaOH, as base-catalyst. NaOH catalyzed syntheses usually require high temperature (>80 °C) and large reaction medium volume to trigger MSN formation and limit aggregation. Here, a successful modulation of MSNs size from 40 up to 150 nm is demonstrated to be achieved by purposely balancing synthesis conditions, being able, in addition, to keep reaction temperature not higher than 50 °C (30 °C and 50 °C, respectively) and reaction mixture volume low. Through a comprehensive and in-depth systematic morphologi-cal and structural investigation, the mechanism and kinetics that sustain the control of MSNs size in such low dimensional regime are defined, highlighting that modulation of size and pores of the structures are mainly mediated by base concentration, reaction time and temperature and ageing, for the homogenous phase approach, and by temperature for the two-phase synthesis. Finally, an in vitro study is performed on bEnd.3 cells to investigate on the cytotoxicity of the MNSs
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