292 research outputs found

    A Fast Visible Camera Divertor-Imaging Diagnostic on DIII-D

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    In recent campaigns, the Photron Ultima SE fast framing camera has proven to be a powerful diagnostic when applied to imaging divertor phenomena on the National Spherical Torus Experiment (NSTX). Active areas of NSTX divertor research addressed with the fast camera include identification of types of EDGE Localized Modes (ELMs)[1], dust migration, impurity behavior and a number of phenomena related to turbulence. To compare such edge and divertor phenomena in low and high aspect ratio plasmas, a multi-institutional collaboration was developed for fast visible imaging on NSTX and DIII-D. More specifically, the collaboration was proposed to compare the NSTX small type V ELM regime [2] and the residual ELMs observed during Type I ELM suppression with external magnetic perturbations on DIII-D[3]. As part of the collaboration effort, the Photron camera was installed recently on DIII-D with a tangential view similar to the view implemented on NSTX, enabling a direct comparison between the two machines. The rapid implementation was facilitated by utilization of the existing optics that coupled the visible spectral output from the divertor vacuum ultraviolet UVTV system, which has a view similar to the view developed for the divertor tangential TV camera [4]. A remote controlled filter wheel was implemented, as was the radiation shield required for the DIII-D installation. The installation and initial operation of the camera are described in this paper, and the first images from the DIII-D divertor are presented

    Including osteoprotegerin and collagen IV in a score-based blood test for liver fibrosis increases diagnostic accuracy

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    BACKGROUND: Noninvasive methods for liver fibrosis evaluation in chronic liver diseases have been recently developed, i.e. transient elastography (Fibroscan™) and blood tests (Fibrometer®, Fibrotest®, and Hepascore®). In this study, we aimed to design a new score in chronic hepatitis C (CHC) by selecting blood markers in a large panel and we compared its diagnostic performance with those of other noninvasive methods. METHODS: Sixteen blood tests were performed in 306 untreated CHC patients included in a multicenter prospective study (ANRS HC EP 23 Fibrostar) using METAVIR histological fibrosis stage as reference. The new score was constructed by non linear regression using the most accurate biomarkers. RESULTS: Five markers (alpha-2-macroglobulin, apolipoprotein-A1, AST, collagen IV and osteoprotegerin) were included in the new function called Coopscore©. Using the Obuchowski Index, Coopscore© shows higher diagnostic performances than for Fibrometer®, Fibrotest®, Hepascore® and Fibroscan™ in CHC. Association between Fibroscan™ and Coopscore© might avoid 68% of liver biopsies for the diagnosis of significant fibrosis. CONCLUSION: Coopscore© provides higher accuracy than other noninvasive methods for the diagnosis of liver fibrosis in CHC. The association of Coopscore© with Fibroscan™ increases its predictive value
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