474 research outputs found

    Occupational hazards and injuries among oil palm (Elaeis guineensis Jacq.) farmers in the Kwaebibirem District in the Eastern Region of Ghana

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    Oil palm (Elaeis guineensis Jacq.) production in Ghana is associated with high levels of injury mainly because of the use of manual labour with little use of machinery. Using descriptive survey design, 100 oil palm farmers (50 males and 50 females) selected from each of the five-oil palm growing communities in the Kwaebibirem District of the Eastern Region, Ghana, were interviewed to identify the leading occupational hazards and injuries among oil palm farmers. The study showed that the major injuries farmers encountered during pre-planting operations were cutlass injury, stump injury, bee/wasp sting, general body pains and snake bites. Harvesting operations recorded body pains, objects on eyes, harvesting tool injury, snake bites and mattock injury as the major injuries, while post-harvest operations also recorded waist pains, injury on finger nails, cutlass injury and general body pains. Besides, the study showed significant difference between injuries experienced by both male and female oil palm farmers on their farms. The paper calls for sustained safety education and awareness creation on precautionary measures, and first aid operations at the farm level with special emphasis on the mandatory use of personal protective equipment

    Knowledge and information gaps in sanitation: Ghana

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    The government of Ghana has since the late eighties pursued an ambitious decentralisation programme which seeks to devolve all responsibilities for planning and implementation of environmental sanitation schemes to the provincial local governments (District Assemblies). The decentralisation effort has been accompanied by a reform of the water and sanitation sector with emphasis on decentralised planning of water and sanitation projects, cost recovery, community ownership and management and increased private sector involvement in the delivery of services. However, the general perception is that efforts at improving sanitation have not been successful in ensuring a sustained development of the sub-sector. Current policies and strategies have failed to develop the required capacity and ensure the mobilisation of resources for addressing the enormous challenges within the sub-sector. Indeed the fast rate of urbanisation and population growth has worsened the situation over the years. The WELL Resource Centre Network (RCN) is funded by the UK Government’s Department for International Development (DFID). The RCN provides service and resources for DFID and its partner agencies. Within the framework of WELL activities, TREND Group, a Resource Centre located in Ghana and a partner within the WELL Network, carried out a study of the sanitation sub-sector in Ghana between May and August 2002, to highlight the information and knowledge management gaps. This paper presents a brief summary of findings, analysis and recommendations

    Nitrogen fertilizer management strategy for oil palm-maize intercropping system in the semi-deciduous forest zone of Ghana

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      In an attempt to increase yield of maize in oil palm-maize intercropping system, farmers resort to indiscriminate cutting of fronds of palms leading to low yield of oil palm. This study evaluated the impact of different N fertilizer levels on maize varieties in oil palm-maize intercropping system. The economics of nitrogen application was also studied. The treatments were: T1-Sole oil palm, T2-Oil palm+‘Omankwa’, T3-Oil palm+‘Abelehi’ and T4-Oil palm+ ‘Obatanpa’. The crop associations were superimposed with nitrogen fertilizer levels as sub-treatments at N0- N0:P0:K0, N1-N60:P60:K60, and N2-N120:P60:K60 per ha. The experiment was a split plot design with 4 replications. There was no significant difference (p< 0.05) between maize varieties across seasons for both maize yield and aboveground biomass though ‘Omankwa’ was promising across seasons and more responsive to nitrogen application. Across the three maize varieties, N60P60K60 was significantly higher (p<0.05) by 40% and 17% for maize yield and aboveground biomass respectively as compared to N0:P0:K0. The study recommends N60P60P60 fertilizer level and further states that to improve fertilizer adoption, government should subsidize fertilizer cost for farmers to purchase. The outcome of cost benefit analysis revealed that return per cash invested favored cropping system with N60:P60:K60 and season with less water stress

    Assessment of nutrients status of areas supporting optimum oil palm (Elaeis guineensis Jacq. L) cultivation in Ghana

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    In Ghana, information on the fertility status to support oil palm growth and productivity and possible fertilizer recommendation is not common. The objective of this study was to assess the nutrition-related limitations to production of oil palm across areas climatically delineated as optimum for sustainable oil palm production. Based on Ghana Interim Soil Classification System, benchmark soils identified in these areas were: Temang (Lixisols), Akroso (Acrisol), Kokofu (Alisols), Basitia (Acrislos), Firam (Acrisols) and Nkwanta (Acrisols). Results indicated generally strongly acidic soil and exchangeable acidity values obtained were high and consistent with very acidic soil conditions. There were generally- high C: N ratios (>20) except some few sites, thus supplementary nitrogen is required to reduce C: N ratio and improve N availability. The Total Exchangeable Bases (TEB), Effective Cation Exchange Capacity (ECEC) and available P values were less than the optimum values for sustainable oil palm production. Both soil and foliar analysis indicated that soils in areas assessed have low soil fertility with relatively good soil physical conditions. It is recommended that instead of superphosphate fertilizer application, rock phosphate should be administered due to high acidity. Raising the low ECEC levels of the soil calls for composted empty fruit bunches incorporation

    Missed Opportunities for the Diagnosis of Pulmonary Tuberculosis in Ashanti and Western Regions of Ghana; Polymerase Chain Reaction, A Better Tool

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    The diagnosis of Pulmonary Tuberculosis (PTB) has mainly relied on sputum microscopy and culture. The use of molecular techniques such as the Polymerase Chain Reaction (PCR) and its overwhelming advantages compared with conventional diagnostic methodologies cannot be overemphasized. The main aim of this work was to compare the diagnostic sensitivities of microscopy, culture and PCR. Suspected PTB sputum samples were prospectively collected from six hospitals in the Ashanti and Western regions of Ghana. Microscopy was carried out on all samples at the field sites. Apart from culture and PCR, repeat sputum microscopy was carried out in the laboratories of the Kumasi Centre for Collaborative Research (KCCR). Out of the total 425 cases recruited for the study, 123 (29.0%) were smear positive on site in contrast to 275 (64.7%) positivity rate at KCCR. Regarding culture, 254 (59.9%) samples were culture positive whilst PCR technique using INS 1&2 and PR 8&9 primers were positive in 59.9 % and 56% of cases respectively. The proportion of missed positive cases of microscopy were 131 (51%) compared with culture and 1.1% missed cases when compared with PCR. The sensitivity and specificity of microscopy were 123/254 (48.4%) and 154/302 (50.99%). The study confirms the superiority of PCR in the diagnosis of PTB and indicates that a substantial proportion of PTB cases are missed when microscopy alone is used. In areas where the incidence of PTB is high and at referral hospitals, PCR can be done to augment the diagnosis of TB.Keywords: Pulmonary Tuberculosis, Sputum Microscopy, Culture, Polymerase Chain Reactio

    The Politics of Service Delivery Reform

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    This article identifies the leaders, the supporters and the resisters of public service reform. It adopts a principal–agent framework, comparing reality with an ‘ideal’ situation in which citizens are the principals over political policy-makers as their agents, and policy-makers are the principals over public service officials as their agents. Reform in most developing countries is complicated by an additional set of external actors — international financial institutions and donors. In practice, international agencies and core government officials usually act as the ‘principals’ in the determination of reforms. The analysis identifies the interests involved in reform, indicating how the balance between them is affected by institutional and sectoral factors. Organizational reforms, particularly in the social sectors, present greater difficulties than first generation economic policy reforms

    ZNF217 confers resistance to the pro-apoptotic signals of paclitaxel and aberrant expression of Aurora-A in breast cancer cells

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    <p>Abstract</p> <p>Background</p> <p>ZNF217 is a candidate oncogene located at 20q13, a chromosomal region frequently amplified in breast cancers. The precise mechanisms involved in ZNF217 pro-survival function are currently unknown, and utmost importance is given to deciphering the role of ZNF217 in cancer therapy response.</p> <p>Results</p> <p>We provide evidence that stable overexpression of ZNF217 in MDA-MB-231 breast cancer cells conferred resistance to paclitaxel, stimulated cell proliferation <it>in vitro </it>associated with aberrant expression of several cyclins, and increased tumor growth in mouse xenograft models. Conversely, siRNA-mediated silencing of ZNF217 expression in MCF7 breast cancer cells, which possess high endogenous levels of ZNF217, led to decreased cell proliferation and increased sensitivity to paclitaxel. The paclitaxel resistance developed by ZNF217-overexpressing MDA-MB-231 cells was not mediated by the ABCB1/PgP transporter. However, ZNF217 was able to counteract the apoptotic signals mediated by paclitaxel as a consequence of alterations in the intrinsic apoptotic pathway through constitutive deregulation of the balance of Bcl-2 family proteins. Interestingly, ZNF217 expression levels were correlated with the oncogenic kinase Aurora-A expression levels, as ZNF217 overexpression led to increased expression of the Aurora-A protein, whereas ZNF217 silencing was associated with low Aurora-A expression levels. We showed that a potent Aurora-A kinase inhibitor was able to reverse paclitaxel resistance in the ZNF217-overexpressing cells.</p> <p>Conclusion</p> <p>Altogether, these data suggest that ZNF217 might play an important role in breast neoplastic progression and chemoresistance, and that Aurora-A might be involved in ZNF217-mediated effects.</p

    District-led School Turnaround: Aiming for Ambitious and Equitable Instruction in Shelby County’s iZone

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    The Shelby County iZone is a district-led effort to dramatically improve, or “turn around,” 23 of the lowest performing schools in Tennessee in the 15th largest district in the country. Despite circumstances that have derailed many past reforms, iZone schools have made statistically significant and educationally meaningful gains in mathematics and English language arts (ELA) (Zimmer, Henry, Kho, & Viano, 2015). This report presents the findings of a multi-year research project that examined the evolution of the iZone as it shifted its strategy from school-level autonomy to one that featured a common curriculum, shared pedagogy, and collegial learning. The analysis delves into the challenges that iZone leaders, principals, and teachers confronted in coping with the needs of a student population mired in intergeneration poverty, rigorous performance standards, and a stringent accountability system. The results illuminate the importance of multi-level system re-design, continuous improvement, and compromise and negotiation among key stakeholder groups
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