Looking for the left sneutrino LSP with displaced-vertex searches

We analyze a displaced dilepton signal expected at the LHC for a tau left sneutrino as the lightest supersymmetric particle with a mass in the range $45$-$100$ GeV. The sneutrinos are pair produced via a virtual $W$, $Z$ or $\gamma$ in the $s$ channel and, given the large value of the tau Yukawa coupling, their decays into two dileptons or a dilepton plus missing transverse energy from neutrinos can be significant. The discussion is carried out in the $\mu \nu$SSM, where the presence of $R$-parity violating couplings involving right-handed neutrinos solves the $\mu$ problem and can reproduce the neutrino data. To probe the tau left sneutrinos we compare the predictions of the $\mu \nu$SSM with the ATLAS search for long-lived particles using displaced lepton pairs in $pp$ collisions at $\sqrt s= 8$ TeV, allowing us to constrain the parameter space of the model. We also consider an optimization of the trigger requirements used in existing displaced-vertex searches by means of a High Level Trigger that exploits tracker information. This optimization is generically useful for a light metastable particle decaying into soft charged leptons. The constraints on the sneutrino turn out to be more stringent. We finally discuss the prospects for the $13$ TeV LHC searches as well as further potential optimizations.Comment: Version published in PRD, discussions expanded, references added, LEP and LHC constraints discussed in more detail, 29 pages, 9 figures, 9 table

Explaining muon g-2 data in the μνSSM

We analyze the anomalous magnetic moment of the muon $$g-2$$ in the $$\mu \nu$$SSM. This R-parity violating model solves the $$\mu$$ problem reproducing simultaneously neutrino data, only with the addition of right-handed neutrinos. In the framework of the $$\mu \nu$$SSM, light left muon-sneutrino and wino masses can be naturally obtained driven by neutrino physics. This produces an increase of the dominant chargino-sneutrino loop contribution to muon $$g-2$$, solving the gap between the theoretical computation and the experimental data. To analyze the parameter space, we sample the $$\mu \nu$$SSM using a likelihood data-driven method, paying special attention to reproduce the current experimental data on neutrino and Higgs physics, as well as flavor observables such as B and $$\mu$$ decays. We then apply the constraints from LHC searches for events with multi-leptons + MET on the viable regions found. They can probe these regions through chargino–chargino, chargino–neutralino and neutralino–neutralino pair production. We conclude that significant regions of the parameter space of the $$\mu \nu \mathrm{SSM}$$ can explain muon $$g-2$$ data

Correction: Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling

Correction de l'article DOI: 10.1371/journal.pbio.100246

Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world

Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic. Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality. Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States. Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis. Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection

La population particulièrement vulnérable du point de vue de la police : étrangers, mineurs, personnes âgées et autres groupes vulnérables.

International audienc

La population particulièrement vulnérable du point de vue de la police : étrangers, mineurs, personnes âgées et autres groupes vulnérables.

International audienc

Le phénomène de la prostitution : la coopération franco-espagnole dans la lutte contre la traite des êtres humains

International audienceL'intention des auteurs a été de préparer un Livre blanc sur la traite des êtres humains à des fins d'exploitation sexuelle dans une perspective globale, européenne et franco-espagnole. Partant de la distinction entre la prostitution et la traite des êtres humains. cette fin, les différents aspects de ces activités sont analysés. Premièrement, en ce qui concerne la traite des êtres humains, le scénario européen est analysé en tenant compte des règles d'incrimination, de coordination juridique et de coopération juridictionnelle, ainsi que de la protection des victimes. Les mesures financières de lutte contre la traite font également l'objet d'analyses. cet égard, il convient de souligner l'adoption de types criminels qui poursuivent le blanchiment d'argent, ainsi que la saisie de toutes les ressources économiques provenant de la traite des êtres humains. Deuxièmement, le phénomène répandu de la prostitution est abordé d'un point de vue social et, surtout, juridique. cette fin, la différence de traitement juridique du phénomène de la prostitution en Europe est examinée du point de vue prohibitionniste au point de vue abolitionniste et réglementaire. Les différents aspects juridico-administratifs de la prostitution sont également analysés, ainsi que ceux qui se réfèrent à des questions aussi diverses que les conséquences, la fiscalité, le travail, la réglementation sur le contrôle de l'exercice de la prostitution dans les rues et les espaces publics, ainsi que dans certains lieux spécifiques. Enfin, cette section traite des règles administratives en matière de prévention, de sensibilisation, de sensibilisation, de sensibilisation, de formation, de recherche et de contrôle de la publicité, qui sont liées à l'activité de l'Administration en matière de soutien et d'assistance aux victimes de la traite

Le phénomène de la prostitution : la coopération franco-espagnole dans la lutte contre la traite des êtres humains

International audienceL'intention des auteurs a été de préparer un Livre blanc sur la traite des êtres humains à des fins d'exploitation sexuelle dans une perspective globale, européenne et franco-espagnole. Partant de la distinction entre la prostitution et la traite des êtres humains. cette fin, les différents aspects de ces activités sont analysés. Premièrement, en ce qui concerne la traite des êtres humains, le scénario européen est analysé en tenant compte des règles d'incrimination, de coordination juridique et de coopération juridictionnelle, ainsi que de la protection des victimes. Les mesures financières de lutte contre la traite font également l'objet d'analyses. cet égard, il convient de souligner l'adoption de types criminels qui poursuivent le blanchiment d'argent, ainsi que la saisie de toutes les ressources économiques provenant de la traite des êtres humains. Deuxièmement, le phénomène répandu de la prostitution est abordé d'un point de vue social et, surtout, juridique. cette fin, la différence de traitement juridique du phénomène de la prostitution en Europe est examinée du point de vue prohibitionniste au point de vue abolitionniste et réglementaire. Les différents aspects juridico-administratifs de la prostitution sont également analysés, ainsi que ceux qui se réfèrent à des questions aussi diverses que les conséquences, la fiscalité, le travail, la réglementation sur le contrôle de l'exercice de la prostitution dans les rues et les espaces publics, ainsi que dans certains lieux spécifiques. Enfin, cette section traite des règles administratives en matière de prévention, de sensibilisation, de sensibilisation, de sensibilisation, de formation, de recherche et de contrôle de la publicité, qui sont liées à l'activité de l'Administration en matière de soutien et d'assistance aux victimes de la traite

Reduction of cardiac imaging tests during the COVID-19 pandemic: The case of Italy. Findings from the IAEA Non-invasive Cardiology Protocol Survey on COVID-19 (INCAPS COVID)

Background: In early 2020, COVID-19 massively hit Italy, earlier and harder than any other European country. This caused a series of strict containment measures, aimed at blocking the spread of the pandemic. Healthcare delivery was also affected when resources were diverted towards care of COVID-19 patients, including intensive care wards. Aim of the study: The aim is assessing the impact of COVID-19 on cardiac imaging in Italy, compare to the Rest of Europe (RoE) and the World (RoW). Methods: A global survey was conducted in May–June 2020 worldwide, through a questionnaire distributed online. The survey covered three periods: March and April 2020, and March 2019. Data from 52 Italian centres, a subset of the 909 participating centres from 108 countries, were analyzed. Results: In Italy, volumes decreased by 67% in March 2020, compared to March 2019, as opposed to a significantly lower decrease (p &lt; 0.001) in RoE and RoW (41% and 40%, respectively). A further decrease from March 2020 to April 2020 summed up to 76% for the North, 77% for the Centre and 86% for the South. When compared to the RoE and RoW, this further decrease from March 2020 to April 2020 in Italy was significantly less (p = 0.005), most likely reflecting the earlier effects of the containment measures in Italy, taken earlier than anywhere else in the West. Conclusions: The COVID-19 pandemic massively hit Italy and caused a disruption of healthcare services, including cardiac imaging studies. This raises concern about the medium- and long-term consequences for the high number of patients who were denied timely diagnoses and the subsequent lifesaving therapies and procedures