Chemical composition and biological activities of Daucus aureus essential oils from Eastern Algeria

The aim of this study was to investigate the chemical composition of the essential oils of three populations of Daucus aureus from three sites in Eastern Algeria (Setif, Constantine and Oum Elbouaghi) and to test their antibacterial and antioxidant activities. The essential oils were obtained by hydrodistillation and analyzed by GC and GC/MS. The major components were sabinene (30.6% and 36.2%), n-nonane (8.0% and 7.9%), α-pinene (5.5% and 6.3%) and 4-terpineol (4.4% and 6.0%) in D. aureus from Setif and Constantine populations essential oils, respectively; whereas, α-pinene (19.4%), β-pinene (12.0%) and p-cymene (12.2%) were the major components in Oum Elbouaghi essential oil population. The chemical compositions of D. aureus from Eastern Algeria are markedly different from those from Western Algeria, and likely represent new chemotypes. The antimicrobial activity of the essential oils was evaluated against four bacteria and one fungus, using the disc-diffusion method and minimal inhibitory concentration (MIC), whereas, the antioxidant activity of the essential oils was evaluated using the DPPH test. The results showed that the oils have an antimicrobial activity against the microorganisms tested, with minimal inhibitory concentration (MIC) values between 0.97 and 3.23 mg/mL and weaker antioxidant and DPPH radical scavenging activities were found in comparison to butylated hydroxyl toluene (BHT)

Folding Dynamics of DNA G-Quadruplexes Probed by Millisecond Temperature Jump Circular Dichroism

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Constituents from Bupleurum montanum (Coss. & Dur.) (Apiaceae)

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A flavonoid from n-butanol extract of Anthemis pedenculata

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A flavonoid from n-butanol extract of Anthemis pedenculata

International audienceA chemical investigation of the aerial parts of Anthemis pedenculata resulted in six compounds, two of them identified as 3,4,5,6 tetrahydroxy hexene (1) and luteolin 7-O-glucoside (2). The structural elucidation was performed mainly by MS, 1D and 2D NMR spectrum data

Chemical Analysis, Antioxidant, Antimicrobial and Enzyme Inhibitory Effects of Daucus Virgatus (Poir.) Maire Essential oil from Algeria

Essential oils (EO) represent an important source of bioactive molecules and are widely used for their great efficacy relating to their different therapeutic properties. The present study aims to contribute to the valorization of Daucus virgatus (Poir.) Maire, an aromatic and native plant spontaneously growing in the North-Eastern regions of Algeria, by analyzing the chemical composition of its essential oil and evaluating the antioxidant and antimicrobial activities, together with the assay of the enzyme inhibitory effects against alpha-glucosidase and cholinesterase. Daucus virgatus EO was extracted by hydrodistillation and analyzed by gas chromatography-mass spectroscometry analysis (GC-MS). Twenty-one constituents accounting for 98% of the whole components were identified. beta-Pinene (77.9%) and alpha-pinene (7.6%) were the most abundant components. The antimicrobial activity against the pathogen microorganisms Listeria innocua, Salmonella typhimurium, Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis, Escherichia coli and Candida albicans was investigated. The best antimicrobial effect was observed against S. typhimurium and C. albicans, which showed high sensitivity, with inhibition zones ranging between 27.3 and 25 mm; the minimum inhibitory concentrations were 15.63 and 31.25 mu g ml(-1), respectively. In the DPPH test, the essential oil showed a moderate antioxidant effect, with an IC50 value of 39.61 mg ml(-1). D. virgatus EO exhibited an interesting inhibitory effect against alpha-glucosidase enzyme (IC50 = 0.35 mg ml(-1)) compared with the positive control Acarbose (IC50 = 0.24 mg ml(-1)), and a moderate inhibitory effect against cholinesterases enzymes, with IC50 values of 0.33 and 0.20 mg ml(-1) for acetylcholinesterase and butyrylcholinesterase, respectively. D. virgatus EO might be used as a promising source of natural products with potential antimicrobial, antihyperglycemic and anti-Alzheimer effects

Chemical composition, antioxidant and insecticidal activities of a new essential oil chemotype of Pinus nigra ssp. mauritanica (Pinaceae), northern Algeria

Essential oil (EO) of aerial parts (twigs and needles) of an Algerian-Moroccan endemic pine Pinus nigra Arn. ssp. mauritanica (Mair. & Pey.) (Pinaceae) collected in Northern Algeria were extracted by hydrodistillation (HD) and solid phase micro-extraction (SPME). The compounds were analysed using Gas Chromatography (GC) and GC-Mass Spectrometry (GC-MS). The mean oil yield was 0.23%, for twigs and 0.47% for needles. 83 and 91 compounds have been identified for needles and twigs respectively. Chemical divergences from all other studied Black pines worldwide were observed in needles where the major components identified by HD are β-caryophyllene (26.2%), germacrene D (17.2%), α-pinene (9.4%) unveiling a new chemotype. Significative qualitative and quantitative differences were observed in chemical composition, depending on both technics HD and SPME. Twigs showed a higher potential for the antioxidant activities DPPH, ABTS and β-carotene system than EO needles. In other hand, needles revealed a higher activity for all concentrations than twigs with significant differences (p < 0.05). For phosphomolybden tests, both EOs exhibited more significant antioxidant potential compared to the DPPH, ABTS, β-carotene and reducing power systems. Noticeable insecticidal effects with variable rate depending on used plant parts, concentration, duration and frequency of exposure were also observed