Forage Grasses and Legumes with Broad Adaptation for Southeast Asia

A wide range of forages is currently being evaluated by farmers and researchers in seven countries in Southeast Asia. Broadly-adapted species have been identified for fodder banks, grazed systems, tree cropping, erosion control and improved fallows. The most promising accessions to date are Stylosanthes guianensis CIAT 184, Brachiaria decumbens cv Basilisk, Brachiaria humidicola cv Tully and CIAT 6133, CIAT 6780, Centrosema pubescens CIAT 15160 and Andropogon gayanus cv Kent and CIAT 621. Other forages that show promise are Paspalum atratum, Arachis pintoi, and Macroptilium gracile cv. Maldonado. Local seed supply and distribution systems are needed to ensure that these species reach their potential on farms

Galaxy clusters discovered with a Sunyaev-Zel'dovich effect survey

The South Pole Telescope (SPT) is conducting a Sunyaev-Zel'dovich (SZ) effect survey over large areas of the southern sky, searching for massive galaxy clusters to high redshift. In this preliminary study, we focus on a 40 square-degree area targeted by the Blanco Cosmology Survey (BCS), which is centered roughly at right ascension 5h30m, declination -53 degrees. Over two seasons of observations, this entire region has been mapped by the SPT at 95 GHz, 150 GHz, and 225 GHz. We report the four most significant SPT detections of SZ clusters in this field, three of which were previously unknown and, therefore, represent the first galaxy clusters discovered with an SZ survey. The SZ clusters are detected as decrements with greater than 5-sigma significance in the high-sensitivity 150 GHz SPT map. The SZ spectrum of these sources is confirmed by detections of decrements at the corresponding locations in the 95 GHz SPT map and non-detections at those locations in the 225 GHz SPT map. Multiband optical images from the BCS survey demonstrate significant concentrations of similarly colored galaxies at the positions of the SZ detections. Photometric redshift estimates from the BCS data indicate that two of the clusters lie at moderate redshift (z ~ 0.4) and two at high redshift (z >~ 0.8). One of the SZ detections was previously identified as a galaxy cluster using X-ray data from the ROSAT All-Sky Survey (RASS). Potential RASS counterparts (not previously identified as clusters) are also found for two of the new discoveries. These first four galaxy clusters are the most significant SZ detections from a subset of the ongoing SPT survey. As such, they serve as a demonstration that SZ surveys, and the SPT in particular, can be an effective means for finding galaxy clusters.Comment: 11 pages, 3 figures, revised to match published version, uses emulateap

The 10 Meter South Pole Telescope

The South Pole Telescope (SPT) is a 10 m diameter, wide-field, offset Gregorian telescope with a 966-pixel, multi-color, millimeter-wave, bolometer camera. It is located at the Amundsen-Scott South Pole station in Antarctica. The design of the SPT emphasizes careful control of spillover and scattering, to minimize noise and false signals due to ground pickup. The key initial project is a large-area survey at wavelengths of 3, 2 and 1.3 mm, to detect clusters of galaxies via the Sunyaev-Zeldovich effect and to measure the small-scale angular power spectrum of the cosmic microwave background (CMB). The data will be used to characterize the primordial matter power spectrum and to place constraints on the equation of state of dark energy. A second-generation camera will measure the polarization of the CMB, potentially leading to constraints on the neutrino mass and the energy scale of inflation.Comment: 47 pages, 14 figures, updated to match version to be published in PASP 123 903 (May, 2011

Increased genetic contribution to wellbeing during the COVID-19 pandemic

Physical and mental health are determined by an interplay between nature, for example genetics, and nurture, which encompasses experiences and exposures that can be short or long-lasting. The COVID-19 pandemic represents a unique situation in which whole communities were suddenly and simultaneously exposed to both the virus and the societal changes required to combat the virus. We studied 27,537 population-based biobank participants for whom we have genetic data and extensive longitudinal data collected via 19 questionnaires over 10 months, starting in March 2020. This allowed us to explore the interaction between genetics and the impact of the COVID-19 pandemic on individuals' wellbeing over time. We observe that genetics affected many aspects of wellbeing, but also that its impact on several phenotypes changed over time. Over the course of the pandemic, we observed that the genetic predisposition to life satisfaction had an increasing influence on perceived quality of life. We also estimated heritability and the proportion of variance explained by shared environment using variance components methods based on pedigree information and household composition. The results suggest that people's genetic constitution manifested more prominently over time, potentially due to social isolation driven by strict COVID-19 containment measures. Overall, our findings demonstrate that the relative contribution of genetic variation to complex phenotypes is dynamic rather than static

Non-parametric modeling of the intra-cluster gas using APEX-SZ bolometer imaging data

We demonstrate the usability of mm-wavelength imaging data obtained from the APEX-SZ bolometer array to derive the radial temperature profile of the hot intra-cluster gas out to radius r_500 and beyond. The goal is to study the physical properties of the intra-cluster gas by using a non-parametric de-projection method that is, aside from the assumption of spherical symmetry, free from modeling bias. We use publicly available X-ray imaging data from the XMM-Newton observatory and our Sunyaev-Zel'dovich Effect (SZE) imaging data from the APEX-SZ experiment at 150 GHz to de-project the density and temperature profiles for the relaxed cluster Abell 2204. We derive the gas density, temperature and entropy profiles assuming spherical symmetry, and obtain the total mass profile under the assumption of hydrostatic equilibrium. For comparison with X-ray spectroscopic temperature models, a re-analysis of the recent Chandra observation is done with the latest calibration updates. Using the non-parametric modeling we demonstrate a decrease of gas temperature in the cluster outskirts, and also measure the gas entropy profile. These results are obtained for the first time independently of X-ray spectroscopy, using SZE and X-ray imaging data. The contribution of the SZE systematic uncertainties in measuring T_e at large radii is shown to be small compared to the Chandra systematic spectroscopic errors. The upper limit on M_200 derived from the non-parametric method is consistent with the NFW model prediction from weak lensing analysis.Comment: Replaced with the published version; A&A 519, A29 (2010

Ethnic differences in Internal Medicine referrals and diagnosis in the Netherlands

As in other Western countries, the number of immigrants in the Netherlands is growing rapidly. In 1980 non-western immigrants constituted about 3% of the population, in 1990 it was 6% and currently it is more than 10%. Nearly half of the migrant population lives in the four major cities. In the municipality of Rotterdam 34% of the inhabitants are migrants. Health policy is based on the ideal that all inhabitants should have equal access to health care and this requires an efficient planning of health care resources, like staff and required time per patient. The aim of this study is to examine ethnic differences in the use of internal medicine outpatient care, specifically to examine ethnic differences in the reason for referral and diagnosis. Methods We conducted a study with an open cohort design. We registered the ethnicity, sex, age, referral reasons, diagnosis and living area of all ne

Advancing the understanding of treponemal disease in the past and present

Syphilis was perceived to be a new disease in Europe in the late 15th century, igniting a debate about its origin that continues today in anthropological, historical, and medical circles. We move beyond this age-old debate using an interdisciplinary approach that tackles broader questions to advance the understanding of treponemal infection (syphilis, yaws, bejel, and pinta). How did the causative organism(s) and humans co-evolve? How did the related diseases caused by Treponema pallidum emerge in different parts of the world and affect people across both time and space? How are T. pallidum subspecies related to the treponeme causing pinta? The current state of scholarship in specific areas is reviewed with recommendations made to stimulate future work. Understanding treponemal biology, genetic relationships, epidemiology, and clinical manifestations is crucial for vaccine development today and for investigating the distribution of infection in both modern and past populations. Paleopathologists must improve diagnostic criteria and use a standard approach for recording skeletal lesions on archaeological human remains. Adequate contextualization of cultural and environmental conditions is necessary, including site dating and justification for any corrections made for marine or freshwater reservoir effects. Biogeochemical analyses may assess aquatic contributions to diet, physiological changes arising from treponemal disease and its treatments (e.g., mercury), or residential mobility of those affected. Shifting the focus from point of origin to investigating who is affected (e.g., by age/sex or socioeconomic status) and disease distribution (e.g., coastal/ inland, rural/urban) will advance our understanding of the treponemal disease and its impact on people through time