3,761 research outputs found
Chiroptical molecular switches:synthesis and applications
The last decades of the twentieth century can be characterized as a period in which the use of computers for information storage has integrated in all parts of society. The continuously increasing amount of data to be stored and manipulated has urged the need for high speed computers and large storage capacities. One of the most important challenges in this field is the development of materials and techniques to place as much data as possible on the least amount of material. The ultimate goal would be to achieve information storage at the molecular or even at the atomic level;1 processing of data should occur close to the speed of light by the use of alloptical switching devices
Asymmetric 1,4-Additions to 5-Alkoxy-2(5H)-furanones. An Efficient Synthesis of (R)- and (S)-3,4-Epoxy-1-butanol
The synthesis of enantiomerically pure 5-menthyloxy-2(5H)-furanones is described as well as the diastereoselective 1,4-addition of thiols to these butenolides to yield new homochiral C4-synthons. Kinetic resolution of 5-methoxy-2(5H)-furanone, with an enantiomeric excess of 13%, was achieved by cinchonidine catalyzed thiophenol addition. The synthetic utility of the asymmetric thiol additions is illustrated in an efficient route to enantiomerically pure (R)- and (S)-3,4-epoxy-1-butanol
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