25,179 research outputs found

    Origin of 21+2_1^+ Excitation Energy Dependence on Valence Nucleon Numbers

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    It has been shown recently that a simple formula in terms of the valence nucleon numbers and the mass number can describe the essential trends of excitation energies of the first 2+2^+ states in even-even nuclei. By evaluating the first order energy shift due to the zero-range residual interaction, we find that the factor which reflects the effective particle number participating in the interaction from the Fermi orbit governs the main dependence of the first 2+2^+ excitation energy on the valence nucleon numbers.Comment: 9 pages, 5 figure

    Morphology-dependent trends of galaxy age with environment in Abell 901/902 seen with COMBO-17

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    We investigate correlations between galaxy age and environment in the Abell 901/2 supercluster for separate morphologies. Using COMBO-17 data, we define a sample of 530 galaxies, complete at MV5logh<18M_V -5\log h<-18 on an area of 3.5×3.53.5\times 3.5 (Mpc/hh)2^2. We explore several age indicators including an extinction-corrected residual from the colour-magnitude relation (CMR). As a result, we find a clear trend of age with density for galaxies of all morphologies that include a spheroidal component, in the sense that galaxies in denser environments are older. This trend is not seen among Scd/Irr galaxies since they all have young ages. However, the trend among the other types is stronger for fainter galaxies. While we also see an expected age-morphology relation, we find no evidence for a morphology-density relation at fixed age.Comment: Accepted for publication in MNRAS (Letters

    Neural precursor cells derived from induced pluripotent stem cells exhibit reduced susceptibility to infection with a neurotropic coronavirus.

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    The present study examines the susceptibility of mouse induced pluripotent stem cell-derived neural precursor cells (iPSC-NPCs) to infection with the neurotropic JHM strain of mouse hepatitis virus (JHMV). Similar to NPCs derived from striatum of day 1 postnatal GFP-transgenic mice (GFP-NPCs), iPSC-derived NPCs (iPSC-NPCs) are able to differentiate into terminal neural cell types and express MHC class I and II in response to IFN-γ treatment. However, in contrast to postnatally-derived NPCs, iPSC-NPCs express low levels of carcinoembryonic antigen-cell adhesion molecule 1a (CEACAM1a), the surface receptor for JHMV, and are less susceptible to infection and virus-induced cytopathic effects. The relevance of this in terms of therapeutic application of NPCs resistant to viral infection is discussed

    Insertion of the CXC chemokine ligand 9 (CXCL9) into the mouse hepatitis virus genome results in protection from viral-induced encephalitis and hepatitis.

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    The role of the CXC chemokine ligand 9 (CXCL9) in host defense following infection with mouse hepatitis virus (MHV) was determined. Inoculation of the central nervous system (CNS) of CXCL9-/- mice with MHV resulted in accelerated and increased mortality compared to wild type mice supporting an important role for CXCL9 in anti-viral defense. In addition, infection of RAG1-/- or CXCL9-/- mice with a recombinant MHV expressing CXCL9 (MHV-CXCL9) resulted in protection from disease that correlated with reduced viral titers within the brain and NK cell-mediated protection in the liver. Survival in MHV-CXCL9-infected CXCL9-/- mice was associated with reduced viral burden within the brain that coincided with increased T cell infiltration. Similarly, viral clearance from the livers of MHV-CXCL9-infected mice was accelerated but independent of increased T cell or NK cell infiltration. These observations indicate that CXCL9 promotes protection from coronavirus-induced neurological and liver disease

    The Collider Phenomenology of Technihadrons in the Technicolor Straw Man Model

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    We discuss the phenomenology of the lightest SU(3)_C singlet and non-singlet technihadrons in the Straw Man Model of low-scale technicolor (TCSM). The technihadrons are assumed to be those arising in topcolor--assisted technicolor models in which topcolor is broken by technifermion condensates. We improve upon the description of the color--singlet sector presented in our earlier paper introducing the TCSM (hep-ph/9903369). These improvements are most important for subprocess energies well below the masses of the technirho and techniomega, and, therefore, apply especially to e+e- colliders such as LEP and a low--energy linear collider. In the color--octet sector, we consider mixing of the gluon, the coloron V_8 from topcolor breaking, and four isosinglet color--octet technirho mesons. We assume, as expected in walking technicolor, that these technirhos decay into qbar-q, gg, and g-technipion final states, but not into technipion pairs. All the TCSM production and decay processes discussed here are included in the event generator Pythia. We present several simulations appropriate for the Tevatron Collider, and suggest benchmark model lines for further experimental investigation.Comment: 42 pages, 7 figure

    Bringing closure to microlensing mass measurement

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    Interferometers offer multiple methods for studying microlensing events and determining the properties of the lenses. We investigate the study of microlensing events with optical interferometers, focusing on narrow-angle astrometry, visibility, and closure phase. After introducing the basics of microlensing and interferometry, we derive expressions for the signals in each of these three channels. For various forecasts of the instrumental performance, we discuss which method provides the best means of measuring the lens angular Einstein radius theta_E, a prerequisite for determining the lens mass. If the upcoming generation of large-aperture, AO-corrected long baseline interferometers (e.g. VLTI, Keck, OHANA) perform as well as expected, theta_E may be determined with signal-to-noise greater than 10 for all bright events. We estimate that roughly a dozen events per year will be sufficiciently bright and have long enough durations to allow the measurement of the lens mass and distance from the ground. We also consider the prospects for a VLTI survey of all bright lensing events using a Fisher matrix analysis, and find that even without individual masses, interesting constraints may be placed on the bulge mass function, although large numbers of events would be required.Comment: 23 pages, aastex, submitted to Ap

    Direct radiative capture of p-wave neutrons

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    The neutron direct radiative capture (DRC) process is investigated, highlighting the role of incident p-wave neutrons. A set of calculations is shown for the 12-C(n,gamma) process at incoming neutron energies up to 500 keV, a crucial region for astrophysics. The cross section for neutron capture leading to loosely bound s, p and d orbits of 13-C is well reproduced by the DRC model demonstrating the feasibility of using this reaction channel to study the properties of nuclear wave functions on and outside the nuclear surface. A sensitivity analysis of the results on the neutron-nucleus interaction is performed for incident s- as well as p-waves. It turned out that the DRC cross section for p-wave neutrons is insensitive to this interaction, contrary to the case of incident s-wave neutrons. PACS number(s): 25.40Lw,21.10Gv,23.40.HcComment: 16 pages, REVTeX file, PostScript file, .dvi fil

    Characteristics of Autism Spectrum Disorder in Sotos Syndrome

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    Sotos syndrome is a congenital overgrowth disorder with an incidence of approximately 1 in 14,000. This study investigated behavioural characteristics of ASD within a large cohort of individuals with Sotos syndrome (n=78). As measured by the Social Responsiveness Scale, second edition (SRS-2), 65 participants (83.33%) met clinical cut-off (T-score ≥60). There was no significant gender difference in symptom severity. There was a significant effect of age, with lower scores observed in early childhood and adulthood, compared to childhood. Furthermore, individuals with Sotos syndrome appear to display a trait profile that is similar to that identified in ASD. Overall, these findings indicate that the majority of individuals with Sotos syndrome display clinically significant behavioural symptomatology associated with ASD
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