25,179 research outputs found
Origin of Excitation Energy Dependence on Valence Nucleon Numbers
It has been shown recently that a simple formula in terms of the valence
nucleon numbers and the mass number can describe the essential trends of
excitation energies of the first states in even-even nuclei. By
evaluating the first order energy shift due to the zero-range residual
interaction, we find that the factor which reflects the effective particle
number participating in the interaction from the Fermi orbit governs the main
dependence of the first excitation energy on the valence nucleon numbers.Comment: 9 pages, 5 figure
Morphology-dependent trends of galaxy age with environment in Abell 901/902 seen with COMBO-17
We investigate correlations between galaxy age and environment in the Abell
901/2 supercluster for separate morphologies. Using COMBO-17 data, we define a
sample of 530 galaxies, complete at on an area of (Mpc/). We explore several age indicators including an
extinction-corrected residual from the colour-magnitude relation (CMR). As a
result, we find a clear trend of age with density for galaxies of all
morphologies that include a spheroidal component, in the sense that galaxies in
denser environments are older. This trend is not seen among Scd/Irr galaxies
since they all have young ages. However, the trend among the other types is
stronger for fainter galaxies. While we also see an expected age-morphology
relation, we find no evidence for a morphology-density relation at fixed age.Comment: Accepted for publication in MNRAS (Letters
Neural precursor cells derived from induced pluripotent stem cells exhibit reduced susceptibility to infection with a neurotropic coronavirus.
The present study examines the susceptibility of mouse induced pluripotent stem cell-derived neural precursor cells (iPSC-NPCs) to infection with the neurotropic JHM strain of mouse hepatitis virus (JHMV). Similar to NPCs derived from striatum of day 1 postnatal GFP-transgenic mice (GFP-NPCs), iPSC-derived NPCs (iPSC-NPCs) are able to differentiate into terminal neural cell types and express MHC class I and II in response to IFN-γ treatment. However, in contrast to postnatally-derived NPCs, iPSC-NPCs express low levels of carcinoembryonic antigen-cell adhesion molecule 1a (CEACAM1a), the surface receptor for JHMV, and are less susceptible to infection and virus-induced cytopathic effects. The relevance of this in terms of therapeutic application of NPCs resistant to viral infection is discussed
Insertion of the CXC chemokine ligand 9 (CXCL9) into the mouse hepatitis virus genome results in protection from viral-induced encephalitis and hepatitis.
The role of the CXC chemokine ligand 9 (CXCL9) in host defense following infection with mouse hepatitis virus (MHV) was determined. Inoculation of the central nervous system (CNS) of CXCL9-/- mice with MHV resulted in accelerated and increased mortality compared to wild type mice supporting an important role for CXCL9 in anti-viral defense. In addition, infection of RAG1-/- or CXCL9-/- mice with a recombinant MHV expressing CXCL9 (MHV-CXCL9) resulted in protection from disease that correlated with reduced viral titers within the brain and NK cell-mediated protection in the liver. Survival in MHV-CXCL9-infected CXCL9-/- mice was associated with reduced viral burden within the brain that coincided with increased T cell infiltration. Similarly, viral clearance from the livers of MHV-CXCL9-infected mice was accelerated but independent of increased T cell or NK cell infiltration. These observations indicate that CXCL9 promotes protection from coronavirus-induced neurological and liver disease
The Collider Phenomenology of Technihadrons in the Technicolor Straw Man Model
We discuss the phenomenology of the lightest SU(3)_C singlet and non-singlet
technihadrons in the Straw Man Model of low-scale technicolor (TCSM). The
technihadrons are assumed to be those arising in topcolor--assisted technicolor
models in which topcolor is broken by technifermion condensates. We improve
upon the description of the color--singlet sector presented in our earlier
paper introducing the TCSM (hep-ph/9903369). These improvements are most
important for subprocess energies well below the masses of the technirho and
techniomega, and, therefore, apply especially to e+e- colliders such as LEP and
a low--energy linear collider. In the color--octet sector, we consider mixing
of the gluon, the coloron V_8 from topcolor breaking, and four isosinglet
color--octet technirho mesons. We assume, as expected in walking technicolor,
that these technirhos decay into qbar-q, gg, and g-technipion final states, but
not into technipion pairs. All the TCSM production and decay processes
discussed here are included in the event generator Pythia. We present several
simulations appropriate for the Tevatron Collider, and suggest benchmark model
lines for further experimental investigation.Comment: 42 pages, 7 figure
Bringing closure to microlensing mass measurement
Interferometers offer multiple methods for studying microlensing events and
determining the properties of the lenses. We investigate the study of
microlensing events with optical interferometers, focusing on narrow-angle
astrometry, visibility, and closure phase. After introducing the basics of
microlensing and interferometry, we derive expressions for the signals in each
of these three channels. For various forecasts of the instrumental performance,
we discuss which method provides the best means of measuring the lens angular
Einstein radius theta_E, a prerequisite for determining the lens mass. If the
upcoming generation of large-aperture, AO-corrected long baseline
interferometers (e.g. VLTI, Keck, OHANA) perform as well as expected, theta_E
may be determined with signal-to-noise greater than 10 for all bright events.
We estimate that roughly a dozen events per year will be sufficiciently bright
and have long enough durations to allow the measurement of the lens mass and
distance from the ground. We also consider the prospects for a VLTI survey of
all bright lensing events using a Fisher matrix analysis, and find that even
without individual masses, interesting constraints may be placed on the bulge
mass function, although large numbers of events would be required.Comment: 23 pages, aastex, submitted to Ap
Direct radiative capture of p-wave neutrons
The neutron direct radiative capture (DRC) process is investigated,
highlighting the role of incident p-wave neutrons. A set of calculations is
shown for the 12-C(n,gamma) process at incoming neutron energies up to 500 keV,
a crucial region for astrophysics. The cross section for neutron capture
leading to loosely bound s, p and d orbits of 13-C is well reproduced by the
DRC model demonstrating the feasibility of using this reaction channel to study
the properties of nuclear wave functions on and outside the nuclear surface. A
sensitivity analysis of the results on the neutron-nucleus interaction is
performed for incident s- as well as p-waves. It turned out that the DRC cross
section for p-wave neutrons is insensitive to this interaction, contrary to the
case of incident s-wave neutrons.
PACS number(s): 25.40Lw,21.10Gv,23.40.HcComment: 16 pages, REVTeX file, PostScript file, .dvi fil
Characteristics of Autism Spectrum Disorder in Sotos Syndrome
Sotos syndrome is a congenital overgrowth
disorder with an incidence of approximately 1 in 14,000.
This study investigated behavioural characteristics of ASD
within a large cohort of individuals with Sotos syndrome
(n=78). As measured by the Social Responsiveness Scale,
second edition (SRS-2), 65 participants (83.33%) met clinical
cut-off (T-score ≥60). There was no significant gender
difference in symptom severity. There was a significant
effect of age, with lower scores observed in early childhood
and adulthood, compared to childhood. Furthermore,
individuals with Sotos syndrome appear to display a trait
profile that is similar to that identified in ASD. Overall,
these findings indicate that the majority of individuals with
Sotos syndrome display clinically significant behavioural
symptomatology associated with ASD
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