Effect of Ficus hispida L. on normal and dexamethasone suppressed wound healing

Ethanolic extract of roots of Ficus hispida was investigated in normal and dexamethasone depressed healing conditions, using incision, excision and dead space wound models in albino rats. The root extract of Ficus hispida has shown the maximum breaking strength compared to control group. The rate of epithelialization and wound contraction in excision model was better as compared to control groups. There was significant increase in granulation tissue weight and hydroxyproline content in dead space model compared to control group. The antihealing effect of dexamethasone was also reverted by the administration of ethanolic extract of Ficus hispida in all the wound models .The results indicated that the root extract of Ficus hispida has a significant wound healing activity and also promotes healing in dexamethasone depressed healing conditions.O extrato etanólico de raízes de Ficus hispida foi ensaiado em ratos albinos normais e em condições de cicatrização deprimida por dexametasona, utilizando modelos de ferida por incisão, excisão e de espaço morto. O extrato da raiz de Ficus hispida mostrou a força máxima de tensão comparativamente ao grupo controle. A velocidade de epitelização e de contração da ferida no modelo de excisão foi melhor do que a dos grupos controles. Houve aumento significativo no peso do tecido de granulação e no conteúdo de hidroxiprolina no modelo de espaço morto comparativamente ao grupo controle. O efeito anticicatrizante da dexametasona foi, também, revertido pela administração do extrato etanólico de Ficus hispida em todos os modelos de feridas. Os resultados indicaram que o extrato de Ficus hispida tem atividade cicatrizante em feridas e, também, promove a cicatrização em condições de depressão de cicatrização pela dexametasona

PHARMACOLOGICAL ACTIVITIES OF CEDRUS DEODARA: AN OVERVIEW

ABSTRACT Doctrines of Ayurveda have momentous value even in the life of present day human life. These principles are based on the extraordinary observations and experimentations at various levels. Hence one cannot easily deny the observations put forward by the philosophers. According to one of its great preceptors Charaka-the dictum of Ayurveda is to maintain health of healthy people and to alleviate disorders in the diseased persons. The references of medicinal uses of herbs are recorded in Rgveda and Atharvaveda. Nighantus, the well-known compilations-are the very rich sources of herbal drug data ranging from identification,collection to therapeutics uses of the drugs. Since previous two decades there has been an increasing status emphasized on screening of herbs for in order to reduce the risk related to diseases. Cedrus deodara, the common cedar is an important plant belonging to the family Conifereae. C. deodara has been proven to have great pharmacological potential with a great utility and usage as folklore medicine, Heart wood is the most important part used medicinally. This review summarized the plant characteristics with their pharmacological activities

PHARMACOLOGICAL ACTIVITIES OF ACHYRANTHUS ASPERA: AN OVERVIEW

ABSTRACT Many plants are essential in human health care, both in self-medication and in national services. India has a great wealth of various naturally occurring plant drugs which have great potential pharmacological activities. A number of medicinal plants are used as rejuvenators as well as for treating various disease conditions. Achyranthes aspera belonging to the family Amaranthaceae is an important medicinal herb found as a weed throughout India. Though almost all of its parts are used in traditional systems of medicines. This review summarized the plant characteristics with their pharmacological activities