Acute Kidney Injury After Percutaneous Coronary Intervention Guided by Intravascular Ultrasound

Purpose We investigated the impact of intravascular ultrasound guidance on reducing the incidence of contrast-induced acute kidney injury (CI-AKI) in patients undergoing percutaneous coronary intervention (PCI). Methods Ninety-nine patients were enrolled in this prospective cohort who were not randomly assigned to angiography-guided percutaneous coronary intervention or intravascular ultrasound-guided percutaneous coronary intervention. The patients were hospitalized at the Vietnam National Heart Institute - Bach Mai Hospital between 2019 and 2020. Acute kidney injury incidence during hospitalization was the primary endpoint. Results A total of 99 patients were divided into two groups: the intravascular ultrasound-guided group (33 participants) and the angiography-guided group (66 participants). The mean ± SD contrast volume of each group was 95.2 ± 37.1 mL and 133.0 ± 36.0 mL for the ultrasound-guided and angiography-guided groups, with P \u3c 0.0001. Intravascular imaging-guided percutaneous coronary intervention (IVUS-guided PCI) was associated with reduced acute kidney injury incidence during hospitalization: 0.0% vs. 12.12% and P = 0.049. Conclusions Intravascular ultrasound is a safe imaging tool that guides percutaneous coronary intervention and significantly reduces the rate of acute kidney injury compared to angiography alone. Patients who have a high chance of experiencing acute kidney injury benefit from using intravascular ultrasound

Clinical evaluation of dengue and identification of risk factors for severe disease: protocol for a multicentre study in 8 countries

Background: The burden of dengue continues to increase globally, with an estimated 100 million clinically apparent infections occurring each year. Although most dengue infections are asymptomatic, patients can present with a wide spectrum of clinical symptoms ranging from mild febrile illness through to severe manifestations of bleeding, organ impairment, and hypovolaemic shock due to a systemic vascular leak syndrome. Clinical diagnosis of dengue and identification of which patients are likely to develop severe disease remain challenging. This study aims to improve diagnosis and clinical management through approaches designed a) to differentiate between dengue and other common febrile illness within 72 h of fever onset, and b) among patients with dengue to identify markers that are predictive of the likelihood of evolving to a more severe disease course. Method/Design: This is a prospective multi-centre observational study aiming to enrol 7–8000 participants aged ≥ 5 years presenting with a febrile illness consistent with dengue to outpatient health facilities in 8 countries across Asia and Latin America. Patients presenting within 72 h of fever onset who do not exhibit signs of severe disease are eligible for the study. A broad range of clinical and laboratory parameters are assessed daily for up to 6 days during the acute illness, and also at a follow up visit 1 week later. Discussion: Data from this large cohort of patients, enrolled early with undifferentiated fever, will be used to develop a practical diagnostic algorithm and a robust clinical case definition for dengue. Additionally, among patients with confirmed dengue we aim to identify simple clinical and laboratory parameters associated with progression to a more severe disease course. We will also investigate early virological and serological correlates of severe disease, and examine genetic associations in this large heterogeneous cohort. In addition the results will be used to assess the new World Health Organization classification scheme for dengue in practice, and to update the guidelines for “Integrated Management of Childhood Illness” used in dengue-endemic countries. Trial registration: NCT01550016. Registration Date: March 7, 201

Associations of Underlying Health Conditions With Anxiety and Depression Among Outpatients: Modification Effects of Suspected COVID-19 Symptoms, Health-Related and Preventive Behaviors

Objectives: We explored the association of underlying health conditions (UHC) with depression and anxiety, and examined the modification effects of suspected COVID-19 symptoms (S-COVID-19-S), health-related behaviors (HB), and preventive behaviors (PB).Methods: A cross-sectional study was conducted on 8,291 outpatients aged 18–85 years, in 18 hospitals and health centers across Vietnam from 14th February to May 31, 2020. We collected the data regarding participant's characteristics, UHC, HB, PB, depression, and anxiety.Results: People with UHC had higher odds of depression (OR = 2.11; p < 0.001) and anxiety (OR = 2.86; p < 0.001) than those without UHC. The odds of depression and anxiety were significantly higher for those with UHC and S-COVID-19-S (p < 0.001); and were significantly lower for those had UHC and interacted with “unchanged/more” physical activity (p < 0.001), or “unchanged/more” drinking (p < 0.001 for only anxiety), or “unchanged/healthier” eating (p < 0.001), and high PB score (p < 0.001), as compared to those without UHC and without S-COVID-19-S, “never/stopped/less” physical activity, drinking, “less healthy” eating, and low PB score, respectively.Conclusion: S-COVID-19-S worsen psychological health in patients with UHC. Physical activity, drinking, healthier eating, and high PB score were protective factors

Structuration spatiale des peuplements zooplanctoniques et fonctionnement hydrodynamique en milieu lagunaire

Dans le but de mieux comprendre certains mécanismes du fonctionnement de l'écosystème lagunaire, ce travail aborde le compartiment zooplanctonique sous l'angle de son organisation spatiale à l'intérieur d'une lagune nord-méditerranéenne (étang de Thau). Un traitement statistique - groupement avec contrainte de contiguïté spatiale - est employé pour faire une partition de la lagune en un certain nombre de zones homogènes du point de vue de leurs peuplements zooplanctoniques. La confrontation des structures biologiques avec les structures physiques (hydrodynamique et hydroclimat) permet de mettre en évidence les points suivants : 1) la signification des différents schémas de répartition des peuplements zooplanctoniques doit être envisagée à courte échelle de temps (quelques jours), ce niveau d'organisation n'ayant pas révélé de structure saisonnière particulière; 2) En revanche, le sens des échanges d'eaux avec la mer joue, lui, un rôle privilégié, structurant et déstructurant - au gré des inversions - l'organisation spatiale du plancton à l'échelle de l'ensemble de la lagun

Structuration spatiale des peuplements zooplanctoniques et fonctionnement hydrodynamique en milieu lagunaire

Dans le but de mieux comprendre certains mécanismes du fonctionnement de l'écosystème lagunaire, ce travail aborde le compartiment zooplanctonique sous l'angle de son organisation spatiale à l'intérieur d'une lagune nord-méditerranéenne (étang de Thau). Un traitement statistique - groupement avec contrainte de contiguïté spatiale - est employé pour faire une partition de la lagune en un certain nombre de zones homogènes du point de vue de leurs peuplements zooplanctoniques. La confrontation des structures biologiques avec les structures physiques (hydrodynamique et hydroclimat) permet de mettre en évidence les points suivants : 1) la signification des différents schémas de répartition des peuplements zooplanctoniques doit être envisagée à courte échelle de temps (quelques jours), ce niveau d'organisation n'ayant pas révélé de structure saisonnière particulière; 2) En revanche, le sens des échanges d'eaux avec la mer joue, lui, un rôle privilégié, structurant et déstructurant - au gré des inversions - l'organisation spatiale du plancton à l'échelle de l'ensemble de la lagun

Perfect impedance-matched left-handed behavior in combined metamaterial

Matching the impedance of a medium to free space, which is usually not available in natural materials, is an important advance in metamaterials. In this paper, we present a simple mechanism for a perfect impedance-matched left-handed metamaterials, that reveals a nearly zero reflection over operating frequency. This finding is based on the independent manipulation of the electric response without any effect on the magnetic one