214 research outputs found

    Sampled-data fuzzy controller for continuous nonlinear systems

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    The sampled-data fuzzy control of nonlinear systems is presented. The consequents of the fuzzy controller rules are linear sampled-data sub-controllers. As a result, the fuzzy controller is a weighted sum of some linear sampled-data sub-controllers that can be implemented by a microcontroller or a digital computer to lower the implementation cost. Consequently, a hybrid fuzzy controller consisting of continuous-time grades of memberships and discrete-time sub-controller is obtained. The system stability of the fuzzy control system is investigated on the basis of Lyapunov-based approach. The sampling activity introduces discontinuity to complicate the system dynamics and make the stability analysis difficult. The proposed fuzzy controller exhibits a favourable property to alleviate the conservativeness of the stability analysis. Furthermore, linear matrix inequality-based performance conditions are derived to guarantee the system performance of the fuzzy control system. An application example is given to illustrate the merits of the proposed approac

    The role of monocytes and monocyte-derived dendritic cells in type 1 diabetes mellitus and autoimmune thyroid disease

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    Type 1 diabetes mellitus (DM1) and autoimmune thyroid disease (AITD) are organ specific autoimmune diseases in which the immune system is directed against the ß cells and the thyrocytes respectively. The etio-pathogenesis of organ-specific or endocrine autoimmune diseases is complex, polygenic and heavily dependent on various environmental influences. The exact etiology of these diseases remains to be clarified, the pathogenesis is strongly associated with autoimmune phenomena. None of current treatment approaches provide a cure, but represent replacement therapies

    Education in IT Security: A Case Study in Banking Industry

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    The banking industry has been changing incessantlyand facing new combination of risks. Data protection andcorporate security is now one of the major issues in bankingindustry. As the rapid changing on technologies from time totime, the industry should be aware on new technologies in orderto protect information assets and prevent fraud activities. Thispaper begins with literature study of information security issuesand followed by focused-group interviews with five participantswithin the industry and survey analysis of “The global state ofInformation Security survey 2013” which published byPriceWaterhouseCoopers (PWC). Trends and questions werediscussed as well as possible solution. The study suggests that ITsecurity education should be made to different level of staffs suchas executives, professional and general staffs. Besides, thebanking industry should increase company-wide securityawareness and the importance of corporate security which keepthe information and physical assets secure and in a proper way

    Circulating Levels of Adipocyte and Epidermal Fatty Acid–Binding Proteins in Relation to Nephropathy Staging and Macrovascular Complications in Type 2 Diabetic Patients

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    OBJECTIVE—To investigate the relationships of serum adipocyte fatty acid–binding protein (A-FABP) and epidermal fatty acid–binding protein (E-FABP) with renal dysfunction and macrovascular complications in type 2 diabetic patients

    Aetiology of allergic rhinitis in Hong Kong

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    ABSTRACTIn a 1993 survey, allergic rhinitis was identified as the most common allergic disease in Hong Kong, affecting 29.1% of schoolchildren. Recently (1995), the International Study of Asthma and Allergies in Childhood (ISAAC) also reported 44.5% current rhinitis among Hong Kong teenagers. Our objective was to study the aetiology of allergic rhinitis in Hong Kong using serological tests of allergen sensitization. In 57 allergic rhinitis patients and in the same number of age- and sex-matched controls the following were measured: serum total IgE, mixed aeroallergen IgE (Phadiatopℱ) and specific IgE versus house dust mite (HDM), cockroach, cat and dog dander, mould mixture (Penicillium, Cladosporium, Aspergillus and Alternaria species) and four local pollens (Bermuda grass, Timothy, ragweed and mugwort). Compared with controls, allergic rhinitis patients (26 males, 31 females; mean (± SD) age 25 ±11 years) had a significantly elevated serum total IgE concentration (mean ± SEM: 496 ± 88 vs 179 ± 38 kU/L) and an increased proportion of positive Phadiatop (95 vs 33%) and specific IgE tests versus HDM (90 vs 44%) and cockroach (42 vs 9%; Mann-Whitney U-test and χ2 tests all P < 0.005). There was no significant difference in sensitization to other allergens tested. House dust mite and cockroach are ubiquitous in Hong Kong with a warm, humid climate and crowded living conditions. Their identification as aetiological agents of allergic rhinitis should help in the development of environmental strategies for reducing the inhalant allergen load to prevent and control this prevalent and costly health problem in our community

    Return to work, work productivity loss and activity impairment in Chinese breast cancer survivors 12-month post-surgery: a longitudinal study

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    Introduction: Existing evidence of returning-to-work (RTW) after cancer comes predominately from Western settings, with none prospectively examined since the initial diagnostic phase. This study prospectively documents RTW-rate, time-to-RTW, work productivity loss, and activity impairment, within the first-year post-surgery among Chinese women with breast cancer (BCW) and identify potential causal co-variants. Methods: This observational longitudinal study followed 371 Chinese BCW who were employed/self-employed at the time of diagnosis at 4-week post-surgery (baseline). RTW-status and time-to-RTW were assessed at baseline (T1), 4-month (T2), 6-month (T3), and 12-month (T4) post-baseline. WPAI work productivity loss and activity impairment were assessed at T4. Baseline covariates included demographics, medical-related factors, work satisfaction, perceived work demand, work condition, RTW self-efficacy, B-IPQ illness perception, COST financial well-being, EORTC QLQ-C30 and QLQ-BR23 physical and psychosocial functioning, and HADS psychological distress. Results: A 68.2% RTW-rate (at 12-month post-surgery), prolonged delay in RTW (median = 183 days), and significant proportions of T4 work productivity loss (20%), and activity impairment (26%), were seen. BCW who were blue-collar workers with lower household income, poorer financial well-being, lower RTW self-efficacy, poorer job satisfaction, poorer illness perception, greater physical symptom distress, impaired physical functioning, and unfavorable work conditions were more likely to experience undesired work-related outcomes. Discussion: Using a multifactorial approach, effective RTW interventions should focus on not only symptom management, but also to address psychosocial and work-environmental concerns. An organizational or policy level intervention involving a multidisciplinary team comprising nurses, psychologists, occupational health professionals, and relevant stakeholders in the workplace might be helpful in developing a tailored organizational policy promoting work-related outcomes in BCW
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