Neural processes of proactive and reactive controls modulated by motor-skill experiences

This study investigated the experience of open and closed motor skills on modulating proactive and reactive control processes in task switching. Fifty-four participants who were open-skilled

Aqcostic quantification and colour kinesis: evaluation of left atrial and left ventricular function in real time

published_or_final_versio

Non-Gaussian Correlations in the McLerran-Venugopalan Model

We argue that the statistical weight function W[rho] appearing in the McLerran-Venugopalan model of a large nucleus is intrinsically non-Gaussian, even if we neglect quantum corrections. Based on the picture where the nucleus of radius R consists of a collection of color-neutral nucleons, each of radius a<<R, we show that to leading order in alpha_s and a/R only the Gaussian part of W[rho] enters into the final expression for the gluon number density. Thus, the existing results in the literature which assume a Gaussian weight remain valid.Comment: 21 pages with 4 figures (revtex

Multi-domain active sound control and noise shielding

This paper describes an active sound control methodology based on difference potentials. The main feature of this methodology is its ability to automatically preserve “wanted” sound within a domain while canceling “unwanted” noise from outside the domain. This method of preservation of the wanted sounds by active shielding control is demonstrated with various broadband and realistic sound sources such as human voice and music in multiple domains in a one-dimensional enclosure. Unlike many other conventional active control methods, the proposed approach does not require the explicit characterization of the wanted sound to be preserved. The controls are designed based on the measurements of the total field on the boundaries of the shielded domain only, which is allowed to be multiply connected. The method is tested in a variety of experimental cases. The typical attenuation of the unwanted noise is found to be about 20 dB over a large area of the shielded domain and the original wanted sound field is preserved with errors of around 1 dB and below through a broad frequency range up to 1 kHz. © 2011 Acoustical Society of Americ

Single-Molecule Transistors: Electron Transfer in the Solid State

Single-molecule transistors (SMTs) incorporating individual small molecules are unique tools for examining the fundamental physics and chemistry of electronic transport in molecular systems at the single nanometer scale. We describe the fabrication and characterization of such devices, and the synthesis and surface attachment chemistry of novel transition metal complexes that have been incorporated into such SMTs. We present gate-modulated inelastic electron tunneling vibrational spectroscopy of single molecules, strong Kondo physics (TK ∼ 75 K) as evidence of excellent molecule/electrode electronic coupling, and a demonstration that covalent attachment chemistry can produce SMTs that survive repeated thermal cycling to room temperature. We conclude with a look ahead at the prospects for these nanoscale systems

Performance of the international physical activity questionnaire (short form) in subgroups of the Hong Kong chinese population

Background: The International Physical Activity Questionnaire (IPAQ-SF) has been validated and recommended as an efficient method to assess physical activity, but its validity has not been investigated in different population subgroups. We examined variations in IPAQ validity in the Hong Kong Chinese population by six factors: sex, age, job status, educational level, body mass index (BMI), and visceral fat level (VFL).Methods: A total of 1,270 adults (aged 42.9 ± SD 14.4 years, 46.1% male) completed the Chinese version of IPAQ (IPAQ-C) and wore an accelerometer (ActiGraph) for four days afterwards. The IPAQ-C and the ActiGraph were compared in terms of estimated Metabolic Equivalent Task minutes per week (MET-min/wk), minutes spent in activity of moderate or vigorous intensity (MVPA), and agreement in the classification of physical activity.Results: The overall Spearman correlation (ρ) of between the IPAQ-C and ActiGraph was low (0.11 ± 0.03; range in subgroups 0.06-0.24) and was the highest among high VFL participants (0.24 ± 0.05). Difference between self-reported and ActiGraph-derived MET-min/wk (overall 2966 ± 140) was the smallest among participants with tertiary education (1804 ± 208). When physical activity was categorized into over or under 150 min/wk, overall agreement between self-report and accelerometer was 81.3% (± 1.1%; subgroup range: 77.2%-91.4%); agreement was the highest among those who were employed full-time in physically demanding jobs (91.4% ± 2.7%).Conclusions: Sex, age, job status, educational level, and obesity were found to influence the criterion validity of IPAQ-C, yet none of the subgroups showed good validity (ρ = 0.06 to 0.24). IPAQ-SF validity is questionable in our Chinese population. © 2011 Lee et al; licensee BioMed Central Ltd.published_or_final_versio

Differential expression of microRNAs in plasma of patients with colorectal cancer: A potential marker for colorectal cancer screening

Objective: MicroRNAs (miRNAs) have been shown to offer great potential in the diagnosis of cancer. We investigated whether plasma miRNAs could discriminate between patients with and without colorectal cancer (CRC). Methods: This study was divided into three phases: (1) marker discovery using real-time PCR-based miRNA profiling on plasma, corresponding cancerous and adjacent non-cancerous colonic tissues of five patients with CRC, along with plasma from five healthy individuals as controls; (2) marker selection and validation by real-time quantitative RT-PCR on a small set of plasma; and (3) independent validation on a large set of plasma from 90 patients with CRC, 20 patients with gastric cancer, 20 patients with inflammatory bowel disease (IBD) and 50 healthy controls. Results: Of the panel of 95 miRNAs analysed, five were upregulated both in plasma and tissue samples. All the five miRNAs were validated on the plasma of 25 patients with CRC and 20 healthy controls. Both miR-17-3p and miR-92 were significantly elevated in the patients with CRC (p<0.0005). The plasma levels of these markers were significantly reduced after surgery in 10 patients with CRC (p<0.05). Further validation with an independent set of plasma samples (n=180) indicated that miR-92 differentiates CRC from gastric cancer, IBD and normal subjects. This marker yielded a receiver operating characteristic curve area of 88.5%. At a cut-off of 240 (relative expression in comparison to RNU6B snRNA), the sensitivity was 89% and the specificity was 70% in discriminating CRC from control subjects. Conclusion: MiR-92 is significantly elevated in plasma of patients with CRC and can be a potential non-invasive molecular marker for CRC screening.published_or_final_versio

Eikonal Evolution and Gluon Radiation

We give a simple quantum mechanical formulation of the eikonal propagation approximation, which has been heavily used in recent years in problems involving hadronic interactions at high energy. This provides a unified framework for several approaches existing in the literature. We illustrate this scheme by calculating the total, elastic, inelastic and diffractive DIS cross sections, as well as gluon production in high energy hadronic collisions. From the q-qbar-g-component of the DIS cross sections, we straightforwardly derive low x evolution equations for inelastic and diffractive DIS distribution functions. In all calculations, we provide all order 1/N corrections to the results existing in the literature.Comment: 40 pages, LaTeX, 3 eps-figures, typos corrected, to be published in PR

Nonlinear QCD Evolution: Saturation without Unitarization

We consider the perturbative description of saturation based on the nonlinear QCD evolution equation of Balitsky and Kovchegov (BK). Although the nonlinear corrections lead to saturation of the scattering amplitude locally in impact parameter space, we show that they do not unitarize the total cross section. The total cross section for the scattering of a strongly interacting probe on a hadronic target is found to grow exponentially with rapidity. The origin of this violation of unitarity is the presence of long range Coulomb fields away from the saturation region. The growth of these fields with rapidity is not tempered by the nonlinearity of the BK equation.Comment: 4 pages, RevTe