324 research outputs found
Asymmetric correlation matrices: an analysis of financial data
We analyze the spectral properties of correlation matrices between distinct
statistical systems. Such matrices are intrinsically non symmetric, and lend
themselves to extend the spectral analyses usually performed on standard
Pearson correlation matrices to the realm of complex eigenvalues. We employ
some recent random matrix theory results on the average eigenvalue density of
this type of matrices to distinguish between noise and non trivial correlation
structures, and we focus on financial data as a case study. Namely, we employ
daily prices of stocks belonging to the American and British stock exchanges,
and look for the emergence of correlations between two such markets in the
eigenvalue spectrum of their non symmetric correlation matrix. We find several
non trivial results, also when considering time-lagged correlations over short
lags, and we corroborate our findings by additionally studying the asymmetric
correlation matrix of the principal components of our datasets.Comment: Revised version; 11 pages, 13 figure
Fluctuation-driven insulator-to-metal transition in an external magnetic field
We consider a model for a metal-insulator transition of correlated electrons
in an external magnetic field. We find a broad region in interaction and
magnetic field where metallic and insulating (fully magnetized) solutions
coexist and the system undergoes a first-order metal-insulator transition. A
global instability of the magnetically saturated solution precedes the local
ones and is caused by collective fluctuations due to poles in electron-hole
vertex functions.Comment: REVTeX 4 pages, 3 PS figure
Quantum Monte Carlo calculation of the finite temperature Mott-Hubbard transition
We present clear numerical evidence for the coexistence of metallic and
insulating dynamical mean field theory(DMFT) solutions in a half-filled
single-band Hubbard model with bare semicircular density of states at finite
temperatures. Quantum Monte Carlo(QMC) method is used to solve the DMFT
equations. We discuss important technical aspects of the DMFT-QMC which need to
be taken into account in order to obtain the reliable results near the
coexistence region. Among them are the critical slowing down of the iterative
solutions near phase boundaries, the convergence criteria for the DMFT
iterations, the interpolation of the discretized Green's function and the
reduction of QMC statistical and systematic errors. Comparison of our results
with those of other numerical methods is presented in a phase diagram.Comment: 4 pages, 5 figure
On the distribution of the Wigner time delay in one-dimensional disordered systems
We consider the scattering by a one-dimensional random potential and derive
the probability distribution of the corresponding Wigner time delay. It is
shown that the limiting distribution is the same for two different models and
coincides with the one predicted by random matrix theory. It is also shown that
the corresponding stochastic process is given by an exponential functional of
the potential.Comment: 11 pages, four references adde
Synthetic genetic oscillators demonstrate the functional importance of phenotypic variation in pneumococcal-host interactions.
Phenotypic variation is the phenomenon in which clonal cells display different traits even under identical environmental conditions. This plasticity is thought to be important for processes including bacterial virulence, but direct evidence for its relevance is often lacking. For instance, variation in capsule production in the human pathogen Streptococcus pneumoniae has been linked to different clinical outcomes, but the exact relationship between variation and pathogenesis is not well understood due to complex natural regulation. In this study, we use synthetic oscillatory gene regulatory networks (GRNs) based on CRISPR interference (CRISPRi) together with live cell imaging and cell tracking within microfluidics devices to mimic and test the biological function of bacterial phenotypic variation. We provide a universally applicable approach for engineering intricate GRNs using only two components: dCas9 and extended sgRNAs (ext-sgRNAs). Our findings demonstrate that variation in capsule production is beneficial for pneumococcal fitness in traits associated with pathogenesis providing conclusive evidence for this longstanding question
Accelerating universe emergent from the landscape
We propose that the existence of the string landscape suggests the universe
can be in a quantum glass state, where an extremely large viscosity is
generated, and long distance dynamics slows down. At the same time, the short
distance dynamics is not altered due to the separation of time scales. This
scenario can help to understand some controversies in cosmology, for example
the natural existence of slow roll inflation and dark energy in the landscape,
the apparent smallness of the cosmological constant. We see also that moduli
stabilization is no longer necessary. We further identify the glass transition
point, where the viscosity diverges, as the location of the cosmic horizon. We
try to reconstruct the geometry of the accelerating universe from the structure
of the landscape, and find that the metric should have an infinite jump when
crossing the horizon. We predict that the static coordinate metric for dS space
breaks down outside the horizon.Comment: 20 pages, no figures, harvma
Localization of thermal packets and metastable states in Sinai model
We consider the Sinai model describing a particle diffusing in a 1D random
force field. As shown by Golosov, this model exhibits a strong localization
phenomenon for the thermal packet: the disorder average of the thermal
distribution of the relative distance y=x-m(t), with respect to the
(disorder-dependent) most probable position m(t), converges in the limit of
infinite time towards a distribution P(y). In this paper, we revisit this
question of the localization of the thermal packet. We first generalize the
result of Golosov by computing explicitly the joint asymptotic distribution of
relative position y=x(t)-m(t) and relative energy u=U(x(t))-U(m(t)) for the
thermal packet. Next, we compute in the infinite-time limit the localization
parameters Y_k, representing the disorder-averaged probabilities that k
particles of the thermal packet are at the same place, and the correlation
function C(l) representing the disorder-averaged probability that two particles
of the thermal packet are at a distance l from each other. We moreover prove
that our results for Y_k and C(l) exactly coincide with the thermodynamic limit
of the analog quantities computed for independent particles at equilibrium in a
finite sample of length L. Finally, we discuss the properties of the
finite-time metastable states that are responsible for the localization
phenomenon and compare with the general theory of metastable states in glassy
systems, in particular as a test of the Edwards conjecture.Comment: 17 page
Uncovering the Internal Structure of the Indian Financial Market: Cross-correlation behavior in the NSE
The cross-correlations between price fluctuations of 201 frequently traded
stocks in the National Stock Exchange (NSE) of India are analyzed in this
paper. We use daily closing prices for the period 1996-2006, which coincides
with the period of rapid transformation of the market following liberalization.
The eigenvalue distribution of the cross-correlation matrix, , of
NSE is found to be similar to that of developed markets, such as the New York
Stock Exchange (NYSE): the majority of eigenvalues fall within the bounds
expected for a random matrix constructed from mutually uncorrelated time
series. Of the few largest eigenvalues that deviate from the bulk, the largest
is identified with market-wide movements. The intermediate eigenvalues that
occur between the largest and the bulk have been associated in NYSE with
specific business sectors with strong intra-group interactions. However, in the
Indian market, these deviating eigenvalues are comparatively very few and lie
much closer to the bulk. We propose that this is because of the relative lack
of distinct sector identity in the market, with the movement of stocks
dominantly influenced by the overall market trend. This is shown by explicit
construction of the interaction network in the market, first by generating the
minimum spanning tree from the unfiltered correlation matrix, and later, using
an improved method of generating the graph after filtering out the market mode
and random effects from the data. Both methods show, compared to developed
markets, the relative absence of clusters of co-moving stocks that belong to
the same business sector. This is consistent with the general belief that
emerging markets tend to be more correlated than developed markets.Comment: 15 pages, 8 figures, to appear in Proceedings of International
Workshop on "Econophysics & Sociophysics of Markets & Networks"
(Econophys-Kolkata III), Mar 12-15, 200
A novel proviral clone of HIV-2: Biological and phylogenetic relationship to other primate immunodeficiency viruses.
Infectious molecular clones of the human immunodeficiency virus type 2 (HIV-2) will be valuable tools for the study of regulatory gene functions and the development of an animal model for the human acquired immunodeficiency syndrome (AIDS). To this end, we have cloned and sequenced a novel HIV-2 isolate, HIV-2BEN. One clone, designated MK6, is infectious for various human T-cell lines and for human and macaque peripheral blood lymphocytes (PBL), allowing molecular studies of HIV-2 infection and replication. Since MK6 is highly cytopathic in MT-2 and Molt-4 clone 8 cells, antiviral agents and neutralizing sera may be tested. Cluster analysis of HIV-1, HIV-2, and simian immunodeficiency virus (SIV) env and gag genes revealed that HIV-2BEN yielded the earliest node of phylogenetic divergence for all reported HIV-2 sequences. Noise analysis showed that, with the current data, no specification of any branching order can be made among the four groups of primate lentiviruses, HIV-1, HIV-2/SIVSMM/MAC, SIVAGM, and SIVMND
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