34 research outputs found
Analiza korozijskog djelovanja u cilindru brodskoga sporohodnoga dvotaktnog dizelskog motora
DanaÅ”nji trend u razvoju pomorstva i tehnologije opÄenito, a samim time i pritisci brodara, nagnali su proizvoÄaÄe velikih brodskih dvotaktnih sporohodnih dizelskih motora da konstrukcijskim modifikacijama omoguÄe uporabu goriva sve loÅ”ije kvalitete. Takva goriva sadržavaju tvari koje u odreÄenim uvjetima mogu postati vrlo korozivne. Danas se, generalno gledajuÄi, za pogon trgovaÄkih brodova koristi sporohodnim dvotaktnim dizelskim motorima u rasponu snaga od 5,000 do 80,000 kW i to na goriva vrlo loÅ”e kvalitete. Izgaranje takvih goriva u cilindrima motora neminovno uzrokuje stvaranje elektrokemijske i kemijske korozije, te trenje i troÅ”enje elemenata cilindara i ispuÅ”nih vodova. U ovom Äe se radu analizirati problem nastanka korozije i zaÅ”tita kojom se danas služi poradi spreÄavanja korozijskog djelovanja u cilindrima velikih brodskih dvotaktnih sporohodnih dizelskih motora
Analysis of financing sources for start-up companies
This paper presents the development of start-up companies, their types and potential sources of financing with special emphasis on financing ventures in Croatia. The expected scientific contribution supports the defining stages of development for start-ups, as well as their financing sources at each stage. The goal of the research was to investigate whether Croatia has made a shift from traditional to newer methods of financing. Scientific and research contributions of the paper are reflected in the fact that there is a relatively small number of papers, especially in the domestic literature, that address these issues. Therefore, this research can contribute to a better understanding of the financing strategy of entrepreneurial ventures. Presented and interpreted results could be a useful basis and encouragement for a further research in this and similar topics related to the start-up scene at the local as well as the global level
Uticaj DOAK i DOAC-REMOVEĀ® na testove koagulacije u toku testiranja trombofilije kod bolesnika leÄenih primenom DOAK
Background/Aim. Direct oral anticoagulants (DOACs) administration significantly interferes with coagulation as-says. The aim of the study was to evaluate the effect of DOACs and DOAC-RemoveĀ® on coagulation assays dur-ing thrombophilia testing. Methods. The study was car-ried out from January 2019 to the end of June 2020. It in-cluded 30 DOAC-treated patients, 14 females and 16 males aged 23 to 63 (median age 47.6 years), tested for thrombophilia due to venous thromboembolism (VTE). Thrombophilia testing was performed using DOAC-RemoveĀ® tablets (activated charcoal). The results before and after DOAC-RemoveĀ® were compared. Results. Posi-tive lupus anticoagulant (LA) results were observed in 20% apixaban, 100% dabigatran, and 70% rivaroxaban-treated patients, while in samples after DOAC-RemoveĀ®, the LA positivity was observed only in one from the apix-aban group. Before DOAC-RemoveĀ®, the activated pro-tein C (APC) resistance (APC-R) was measurable in 40% dabigatran and 80% rivaroxaban-treated patients, while, after using DOAC-RemoveĀ®, the APC-R was measurable in all cases. Comparing the results obtained from the sam-ples before and after DOAC-RemoveĀ®, a difference was noted in relation to all dilute Russell's viper venom time (dRVVT) coagulation tests, except for the dRVVT ratio in the apixaban group. Clot-based methods for detecting the APC resistance were significantly affected by dabigatran and less by rivaroxaban. Conclusion. DOACs were prac-tically inactivated after the addition of the DOAC-RemoveĀ®, which made it possible to perform analyses for the LA and APC-R testing freely and obtain relevant re-sults.Uvod/Cilj. Primena direktnih oralnih antikoagulansa (DOAK)
znaÄajno utiÄe na testove koagulacije. Cilj rada bio je da se pro-
ceni uticaj DOAK i DOAC-RemoveĀ® tableta (aktivni ugalj) na
testove koagulacije tokom ispitivanja trombofilije. Metode.
Istraživanjem, sprovedenim od januara 2019. do juna 2020.
godine, obuhvaÄeno je 30 bolesnika leÄenih DOAK-om i
testiranih na trombofiliju zbog venskog tromboembolzma
(VTE). Bilo je 14 žena i 16 muŔkaraca, starosti od 23 do 63
godine (medijana 47,6 godina). Ispitivanje trombofilije izvrŔeno
je upotrebom DOAC-RemoveĀ® tableta (aktivni ugalj).
UporeÄivani su rezultati pre i posle primene DOAC-RemoveĀ®.
Rezultati. Pozitivni rezultati za lupus antikoagulantni (LA) test
dobijeni su kod 20% bolesnika leÄenih apiksabanom, kod
100% bolesnika leÄenih dabigatranom i kod 70% leÄenih riva-
roksabanom, a u uzorcima posle DOAC-RemoveĀ® pozitivnost
na LA dobijena je samo kod jednog bolesnika iz grupe leÄnih
apiksabanom. Pre primene DOAC-RemoveĀ®, rezistencija na
aktivisani protein C (activated protein C resistance ā APC-R) bila je
merljiva kod 40% i 80% bolesnika leÄenih dabigatranom, od-
nosno rivaroksabanom, dok je posle primene DOAC-
RemoveĀ®, APC-R bila merljiva u svim sluÄajevima.
UporeÄivanjem rezultata dobijenih iz uzoraka pre i posle
primene DOAC-RemoveĀ®, primeÄena je razlika u odnosu na
sve testove vremena koagulacije izvrŔene razblaženim Russell-
ovim zmijskim otrovom (dilute Russellās viper venom time ā
dRVVT), osim dRVVT u grupi bolesnika leÄenih apiksabanom.
Na koagulacionu metodu za otkrivanje APC-R znaÄajno je uti-
cao dabigatran, a manje rivaroksaban. ZakljuÄak. Nakon
primene DOAC-RemoveĀ® tableta, DOAK su praktiÄno
inaktivisani Å”to je omoguÄilo izvoÄenje analiza za LA i APC-R i
dobijanje relevantnih rezultata testova
Trainer system appliances in early treatment of malocclusions
Orthodontics is dental specialty focused on preventing and treating morphological and functional irregularities of orofacial system in order to establish adequate function of mastication apparatus, good occlusion and pleasant facial appearance. It has been shown that early treatment of orthodontic anomalies during the period of childrenās growth is very important. The purpose of early orthodontic treatment is to eliminate or modify deviant skeletal growth and to stimulate adequate dentoalveolar and skeletal development. As known, the treatment of malocclusions should begin in primary or early mixed dentition, since the status of primary dentition has profound effect on the development of permanent dentition. Functional orthodontic appliances are most commonly used in early orthodontic treatment. The aim of this study was to describe a new prefabricated polyurethane myo-functional appliance clinically proved to be very effective
Multiple Structural Failures of Aortic Homografts Leading to Emergency Surgery
Aortic homografts are composed of aortic roots and variable lengths of the arch and ascending aorta, harvested from donor hearts. They are primarily used in extensive aortic root endocarditis due to its resistance to reinfection. They are, however, prone to structural failure. Redo aortic root surgery is challenging, especially in the setting of aneurysms or pseudoaneurysms (PSAN) lying immediately posterior to the sternum or adhering to it. We present a 43-year-old female with two aortic homograft pseudoaneurysms following her fourth aortic valve and ascending aortic procedure. The first PSAN was described as immediately cranial to proximal homograft anastomosis, measuring 21x8 millimeters. It harbored potential for intraoperative rupture because of its proximity to the posterior sternal table. The second one was 36x20 millimeters, adjacent to the distal homograft anastomosis. The surgical plan entailed institution of peripheral hypothermic cardiopulmonary bypass due to an almost inevitable risk of bleeding from the retrosternal pseudoaneurysm. While the actual sternotomy was uneventful, the PSAN ruptured after sternal retraction. The ensuing massive bleeding was expected and was success- fully managed during hypothermic circulatory arrest. The patient had an unremarkable postoperative course and was discharged home
Supplementary material for the article: MihajloviÄ-LaliÄ, L. E.; DamjanoviÄ, L.; Å umar-RistoviÄ, M.; SaviÄ, A.; Sabo, T. J.; Dondur, V.; GrguriÄ-Å ipka, S. Cytotoxic Pt(IV) and Ru(II) Complexes Containing a Biologically Relevant Edda-Type Ligand: A Comparative Study of Their Thermal Properties. Journal of the Serbian Chemical Society 2016, 81 (8), 897ā905. https://doi.org/10.2298/JSC160320059M
Supplementary material for: [https://doi.org/10.2298/JSC160320059M]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/2325
Supplementary data for the article: Mihajlovic, L.; Radosavljevic, J.; Nordlund, E.; Krstic, M.; Bohn, T.; Smit, J.; Buchert, J.; Cirkovic Velickovic, T. Peanut Protein Structure, Polyphenol Content and Immune Response to Peanut Proteins: In Vivo Are Modulated by Laccase. Food and Function 2016, 7 (5), 2357ā2366. https://doi.org/10.1039/c5fo01325a
Supplementary material for: [https://doi.org/10.1039/c5fo01325a]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/2254
New Topical Treatment of Symptomatic Internal Haemorrhoids in a General Practice Setting
Introduction: Oral usage of flavonoid-based drugs can be successfully applied in the conservative treatment of internal haemorrhoids; however, its efficiency in a form of topical preparations has not been demonstrated yet. The aim of the present study was to determine the efficiency of ointment with propolis extract (containing minimally 115 mg/kg of flavonoid galangin) in relief and suppression of the symptomatic internal haemorrhoids grade 1 and 2 (bleeding, prolapse, pain, and itching).
Methods: This prospective cohort epidemiological study that included 46 participants of both genders, mean age 53.6Ā±14.3 years, was conducted in the general practice setting in Osijek, Croatia and lasted for three months. A specially designed questionnaire was used to collect demographic data and data concerning the haemorrhoid disease symptoms and to evaluate the intensity of the latter data according to the scale defined in the research protocol.
Results: The study showed statistically significant improvements in the intensity of all the symptoms connected with the internal haemorrhoids grade 1 and 2 (p<0.001) during the follow up period, as well as statistically significant differences in proportions of participants with and without of the each of the analysed symptoms before and after the therapy (p<0.001). After three months of therapy with ointment containing propolis extract 82.7% patients (38/46) had none of the analysed symptoms.
Conclusions: Ointment with propolis extract efficiently affected all the analysed symptoms of the haemorrhoid disease thus having a very significant place within the conservative treatment of haemorrhoids
Cytotoxic Pt(IV) and Ru(II) complexes containing a biologically relevant edda-type ligand: A comparative study of their thermal properties
The thermal behaviour of a Pt(IV) and a Ru(II) complex coordinated to dibutyl (S,S)-alpha,alpha'-(1,2-ethanediyldiimino)biscyclohexanepropanoate was investigated using thermogravimetry (TG) and differential scanning calorimetry (DSC). The study included an investigation of the thermal decomposition of these complexes in the temperature range of 30 to 590 degrees C and an evaluation of the activation energy for the first decomposition steps. For both metal complexes, broad DSC peaks indicated complex thermal transformation processes. The two-step decomposition of the Pt(IV) complex started at 175 and ended at about 418 degrees C, leaving elemental platinum as the final residue. On the other hand, the Ru(II) analogue decomposed in three stages. Thermal degradation was evident beginning at 144 degrees C and suggested the decomposition of a coordinated ligand as the dominant process. For this complex, the proposed final residue was RuO2. Kinetic parameters for the first decomposition step were obtained by means of the multi-heating rates method, in this case the Kissinger-Akahira-Sunose (KAS) method. The mean activation energy calculated for 0.2 lt alpha lt 0.8 were 122.0 kJ mol(-1) for the Pt(IV) and 118.9 kJ mol(-1) for the Ru(II) complex and decreased constantly, a characteristic of a multi-step process.Supplementary material: [http://cherry.chem.bg.ac.rs/handle/123456789/3434
Supplementary material for the article: MihajloviÄ-LaliÄ, L. E.; DamjanoviÄ, L.; Å umar-RistoviÄ, M.; SaviÄ, A.; Sabo, T. J.; Dondur, V.; GrguriÄ-Å ipka, S. Cytotoxic Pt(IV) and Ru(II) Complexes Containing a Biologically Relevant Edda-Type Ligand: A Comparative Study of Their Thermal Properties. Journal of the Serbian Chemical Society 2016, 81 (8), 897ā905. https://doi.org/10.2298/JSC160320059M
Supplementary material for: [https://doi.org/10.2298/JSC160320059M]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/2325