A cadaveric study for structural variations of the stomach

Background: The morphology of the stomach taken for the study for its clinical interventions like gastro-oesophagial reflux disorders (GERD) which are very common nowadays because of unusual timing of eating food, stress related jobs, eating of junk foods etc. The obesity now considered to be the 2nd leading cause of death, which can be prevented by gastric reconstructive procedures i.e., the bariatric surgeries.  Methods: The study includes 70 adult cadavers, 28 obtained from the formalin fixed specimens kept for anatomy dissection for 1st year MBBS students from 2009 batch to 2015 batch. The remaining 42 specimens obtained from the postpartum bodies in the Forensic department of Guntur Medical College, Guntur. The abdominal cavity opened according to the incisions in the Cunninghams manual of anatomy. Stomach identified by reflecting anterior abdominal wall. Location noted, shape observed, Length taken, relations blood supply noted, results tabulated.Results: 71.4% specimens are “J” shaped, 14.2% are reverse “L” shaped, 7.2% are cresentic shaped, 7.2% are cylindrical shaped observed. The length is more in “J” shaped specimens. The lower extent of greater curvature at L3 in 71.4% specimens, at L2 in 21.4% specimens, at L4 in 7.2% specimens.Conclusions: The present study discussed about the shape of the stomach and the majority of specimens shown “J” shape. Remaining are reverse “L” shape; cresentic and cylindrical shaped.

Surgical site infections post cesarean section

Background: Surgical site infections are among the most common hospital acquired infections. They make upto 14-16% of inpatient infections. Objective of present study was to evaluate the risk factors associated with surgical site infections and the bacteria causing wound infections in obstetric operations and the antibiotic sensitivity and resistance pattern of the pathogens isolated.Methods: 100 women with wound infection during hospital stay or within 30 days following surgery. Pus samples were collected from the wound site with help of sterile swabs under aseptic precautions and immediately transported to microbiology laboratory for culture and sensitivity.Results: Most of the patients belonged to the age group of 21-25 years, contributing to 55% of the cases. Majority of the women are from rural areas (71%). 57% of the cases were unbooked. 90% of the SSI were seen in emergency surgeries. Anaemia (48%) was the most common medical risk factor followed by hypertensive disorders 25%. The risk of post operative infection has been shown to be proportional to volume of blood loss during cesarean section and duration of surgery. Staphylococcus aureus to be predominant organism of wound infection of which 21% were MRSA followed by Klebsiella and E.coli. The gram negative isolates were 100% resistant to ampicillin followed by 22.5% to third generation cephalosporins and aminoglycosides.Conclusions: Proper assessment of risk factors that predispose to SSI is critical for the development of strategies for reducing the incidence of SSI and for identifying high risk patients requiring intensive postoperative surveillance.

Small-scale traditional spiny lobster fishery at Tikkoti, Calicut

The spiny lobster fishery at Tikkoti though lesser in magnitude is important from the fishery point of view. The traditional fishermen living in three adjacent villages of Kodikal, Kadaloor and Tikkoti are engaged in lobster fishing for the past five decades. The total landings have declined over the years but sudden fall in catches as is seen in 1996-'97 may probably due to natural fluctuations in environmental conditions and change in current pattern rather than due to over fishing. In 1960's fishing was restricted to only three months from August to October and now the fishing begins in September or October and continues up to April or May. Unlike the southwest and southeast coasts where lobster fishing activity has increased several fold due to pressure from the export market, there is no substantial increase in effort at Tikkoti. Establishment of artificial reefs may help in enhancement of lobster population and therefore increase in catches and more revenue for the fishermen

MAGNETIC NANOPARTICLE-BASED APPROACHES IN CANCER THERAPY–A CRITICAL REVIEW

Cancer is definitely one of the leading causes of mortality worldwide. Failure in the efficacy of the standard treatments (chemo-, radiotherapy and surgery), and the severe side effects, resistance of tumor cells to chemotherapeutics have necessitated alternative therapeutic strategies. Magnetic nanoparticles (MNPs) have been assessed as potential cancer therapy materials. Their intrinsic magnetic properties provide a cancer detection, monitoring, and therapy platform based on multimodal theranostics. MNPs can be functionalized by binding them to a wide variety of substances, including chemotherapeutic drugs, radionuclides, nucleic acids, and antibodies. They can be used for drug delivery, magnetic or photothermal induced local hyperthermia and photodynamic therapy aimed at killing cancer cells at the tumor site. MNPs may also be useful to challenge drug resistance. The combination of different options of these treatment modalities offers a synergistic effect and significantly reduces the side effects. The functionalized MNPs may be used to remove the unwanted cells from blood, including leukemia cells and circulating tumor cells that key factors in the metastatic process. Despite numerous successful studies, there are still some unpredictable obstacles relevant to the use of MNPs in cancer therapy. This review mainly focuses on the application of MNPs in cancer treatment, covering future perspectives and challenges aspects

A Study on “Security of Cyber-Physical Systems in the Cloud”

The existing security models are built with certain assumptions. The solutions like distributed accountability, provable data possession (PDP), Third Party Auditing (TPA) and so on are secure as long as the assumptions hold true. To ensure fool proof security for cloud storage security little research has been made on quantum key cryptography. Since the quantum key distribution is unconditionally secure, we propose a new scheme known as Cloud QKDP (Quantum Key Distribution Protocol for Cloud Computing) which exploits the benefits of quantum mechanisms to secure cloud storage and data dynamics. We consider a case study in which three parties such as cloud server, data owner and trusted client have provably secure communications with our proposed scheme which uses random oracle model. Our empirical study revealed mixture of success and failure rates with private and public clouds respectively

Schwannoma arising from hypoglossal nerve in the submandibular triangle: a case report

Hypoglossal schwannomas usually develop in the intracranial portion of the brain. The incidence of hypoglossal schwannomas of the submandibular region is extremely rare. Here we report a case of schwannoma arising from the extracranial hypoglossal nerve in the left submandibular region

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