Modeling CO2 Partitioning at a Carbonate CO2-EOR Site: Permian Basin Field SACROC Unit

Bureau of Economic Geolog

Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses

To understand neurological complications of COVID-19 better both acutely and for recovery, we measured markers of brain injury, inflammatory mediators, and autoantibodies in 203 hospitalised participants; 111 with acute sera (1–11 days post-admission) and 92 convalescent sera (56 with COVID-19-associated neurological diagnoses). Here we show that compared to 60 uninfected controls, tTau, GFAP, NfL, and UCH-L1 are increased with COVID-19 infection at acute timepoints and NfL and GFAP are significantly higher in participants with neurological complications. Inflammatory mediators (IL-6, IL-12p40, HGF, M-CSF, CCL2, and IL-1RA) are associated with both altered consciousness and markers of brain injury. Autoantibodies are more common in COVID-19 than controls and some (including against MYL7, UCH-L1, and GRIN3B) are more frequent with altered consciousness. Additionally, convalescent participants with neurological complications show elevated GFAP and NfL, unrelated to attenuated systemic inflammatory mediators and to autoantibody responses. Overall, neurological complications of COVID-19 are associated with evidence of neuroglial injury in both acute and late disease and these correlate with dysregulated innate and adaptive immune responses acutely

A systematic procedure for reservoir characterization: Annual report for the period October 1, 1985-September 30, 1986

This report deals with a variety of topics all centered around the main goal of making numerical reservoir simulation results conform more closely with geologic descriptions. The first part of the report discusses results on conditional simulations of miscible displacements in randomly heterogeneous permeable media. The focus here is on local or macroscopic dispersion, the dispersion experienced at a fixed point in the medium. Macroscopic dispersivity has many of the same dependencies on reservoir properties as does megascopic dispersivity, but it seems to be less time dependent and is always smaller. We have not discovered a mathematical model to describe its behavior. A major portion of the report deals with statistical descriptions. We investigate the bias and precision of standard measures of heterogeneity, the Lorenz and Dykstra-Parsons coefficient. After this, the work explores the benefits of using a distribution type characterization parameter in exploring heterogeneity. The final major protion of the report describes our mapping efforts on the Page sandstone outcrop in northern Arizona. The mapping is to be used in generating both deterministic descriptions and in calibrating the stochastic descriptions discussed above. 128 refs., 95 figs., 10 tabs